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Source: Journal of the Neurological Sciences
Condition: Ischemic Stroke

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Total 394 results found since Jan 2013.

Cost of treatment failure: Medicare spending on stroke for atrial fibrillation patients not receiving anticoagulation
It is well known that atrial fibrillation (AF) patients not receiving anticoagulants are at higher risk of Ischemic Stroke (IS).
Source: Journal of the Neurological Sciences - September 19, 2023 Category: Neurology Authors: Steven D. Culler, W. Frank Peacock, April W. Simon Source Type: research

The impact of off-hour mechanical thrombectomy therapy on outcomes for acute ischemic stroke: A systematic review and meta-analysis
The impact of off-hours and on-hours mechanical thrombectomy (MT) treatment for acute ischemic stroke (AIS) is not well understood. We conducted a systematic review and met-analysis comparing outcomes between patients undergoing off-hours MT versus on-hours MT.
Source: Journal of the Neurological Sciences - September 11, 2023 Category: Neurology Authors: Sherief Ghozy, Alireza Hasanzadeh, Hassan Kobeissi, Mariam Abdelghaffar, Mahan Shafie, Zahra Beizavi, Amir Hassankhani, Ahmed Y. Azzam, Adam A. Dmytriw, Ramanathan Kadirvel, David F. Kallmes Source Type: research

Factors associated with hemorrhagic transformation after endovascular treatment despite early recanalization
To identify new factors associated with hemorrhagic transformation (HT) despite early recanalization in patients with acute ischemic stroke treated with mechanical thrombectomy.
Source: Journal of the Neurological Sciences - August 30, 2023 Category: Neurology Authors: Antonio Ciacciarelli, Agostino Tessitore, Giulia Fiume, Carmelo Tiberio Curr ò, Alessandra Coglitore, Anna Gardin, Fabrizio Giammello, Francesco Grillo, Mirta Longo, Enrico Mormina, Concetto Fabio Vecchio, Davide Vicari, Rosa Fortunata Musolino, Antonio Source Type: research

Clinical characteristics and intracranial arterial lesions of non-young adult ischemic stroke patients with RNF213 p.R4810K variant
Although RNF213 p.R4810K, a genetic susceptibility variant for moyamoya disease (MMD), is associated with intracranial artery stenosis/occlusion (ICASO), the impact of this variant on ischemic stroke patients in non-young adults is unclear. We aimed to determine the characteristics of non-young adult stroke patients with RNF213 p.R4810K.
Source: Journal of the Neurological Sciences - August 25, 2023 Category: Neurology Authors: Shiori Ogura, Tomoyuki Ohara, Eijirou Tanaka, Shinji Ashida, Keiko Maezono-Kandori, Misaki Hanya, Ikuko Mizuta, Toshiki Mizuno Source Type: research

Association between lipoprotein(a) and ischemic stroke: Fibrinogen as a mediator
Previous studies have reported lipoprotein(a) was related to increased risk of ischemic stroke. However, the role of fibrinogen in their associations was not fully elucidated.
Source: Journal of the Neurological Sciences - July 25, 2023 Category: Neurology Authors: Zhang Youyou, Jia Ruirui, Wang Hui, Li Zhaoyang Source Type: research

Association of admission plasma glucose level and cerebral computed tomographic perfusion deficit volumes
Hyperglycemia in acute ischemic stroke (AIS) is frequent and associated with worse outcome. Yet, strict glycemic control in AIS patients has failed to yield beneficial outcome. So far, the underlying pathophysiological mechanisms of admission hyperglycemia in AIS have remained not fully understood. We aimed to evaluate the yet equivocal association of hyperglycemia with computed tomographic perfusion (CTP) deficit volumes.
Source: Journal of the Neurological Sciences - June 26, 2023 Category: Neurology Authors: Laura Mannism äki, Nicolas Martinez-Majander, Gerli Sibolt, Olli Suomalainen, Katariina Bäcklund, Ahmed Elseoud Abou, Juha Järveläinen, Nina Forss, Sami Curtze Source Type: research

Best medical management versus intravenous thrombolysis for mild non-disabling ischemic stroke: A prospective noninferiority registry study
The efficacy and safety of intravenous thrombolysis uncertain in patients with non-disabling mild ischemic stroke. Our aim was to investigate whether best medical management only is noninferior to intravenous thrombolysis plus best medical management therapy for achieving favorable functional outcome at 90  days.
Source: Journal of the Neurological Sciences - June 16, 2023 Category: Neurology Authors: Xiaopan Cao, Jianfeng Luo, Bing Xu, Ying Xiao, Tuo Yang, Xiaohong Sun, Yi Sui Source Type: research

Ultraearly repeated systemic thrombolysis in recurrent ischemic stroke – A multicentre case study
We analysed outcomes of patients who received off-label repeated thrombolysis with recombinant tissue plasminogen activator for ischemic stroke recurrence within 10  days (ultraearly repeated thrombolysis, UERT).
Source: Journal of the Neurological Sciences - June 14, 2023 Category: Neurology Authors: Thorleif Etgen, Manuel Cappellari, David Černík, Raffi Topakian, Luciano A. Sposato, Philippe Sardag, Hanni Wiestler Source Type: research

Significant increase in mortality and risk of acute ischemic stroke in infective endocarditis patients with subarachnoid hemorrhage secondary to mycotic aneurysms
Infective Endocarditis (IE) patients are known to have a variety of complications with one of the rarest, but serious being cerebral mycotic aneurysm, which can result in subarachnoid hemorrhage (SAH). Using the National In-Patient Sample database, we sought to determine the rate of acute ischemic stroke (AIS) and outcomes in IE- patients with and without SAH. In total, we identified 82,844  IE-patients from 2010 to 2016, of which 641 had a concurrent diagnosis of SAH. IE patients with SAH had a more complicated course, higher mortality rate (OR 4.65 CI 95% 3.9–5.5, P 
Source: Journal of the Neurological Sciences - May 10, 2023 Category: Neurology Authors: Tolga Sursal, Kevin Clare, Eric Feldstein, Jonathan Ogulnick, Bridget Nolan, Zafar Karimov, Andrew Nazarenko, Linda Ye, Yarden Bornovski, Serena Wong, Joshua Goldberg, Stephan A. Mayer, Andrew Bauerschmidt, Marc Y. El Khoury, Hosam Al-Jehani, Chirag D. Ga Source Type: research

Sex-dependent outcomes of recanalization-treated acute ischemic stroke patients at Shamir (Assaf Harofeh) medical center, Israel, 2011 –2020
Sex-based differences in incidence, etiologies, severity and recanalization treatment outcomes of patients with acute ischemic stroke (AIS) have been studied extensively. We set out to determine if there were sex-based differences in outcomes among AIS patients who received recanalization treatments at Shamir (Assaf Harofeh) Medical Center (SMC), Israel, between 2011 and 2020.
Source: Journal of the Neurological Sciences - May 8, 2023 Category: Neurology Authors: Itzhak Kimiagar, Fikri Khiri, Sigal Tal, Ronen Levite, Shani Kalmanovich-Avnery, Rina Aroesty, Sarah Bhonkar, Jochay Wainstein, Gilad Kenan, Nitai Shimon, Ahmed Khadija, Neta Agajani, Sofia Galinskaya, Sharon Wolfson, Zoya Haitov, Eran Kalmanovich, Daniel Source Type: research

Quantitative CTA vascular calcification, atherosclerosis burden, and stroke mechanism in patients with ischemic stroke
Vascular calcification is recognized as the advanced stage of atherosclerosis burden. We hypothesized that vascular calcium quantification in CT angiography (CTA) would be helpful to differentiate large artery atherosclerosis (LAA) from other stroke etiology in patients with ischemic stroke.
Source: Journal of the Neurological Sciences - April 28, 2023 Category: Neurology Authors: Takashi Shimoyama, Sibaji Gaj, Kunio Nakamura, Shivakrishna Kovi, Shumei Man, Ken Uchino Source Type: research

The REMIT scale: A novel prediction scale for embolism in hyperacute stroke with large vessel occlusion
Large vessel occlusion (LVO) in hyperacute ischemic stroke occurs mainly by one of two mechanisms, embolism or atherosclerosis. However, the mechanism is difficult to identify prior to treatment. We aimed to investigate the factors associated with embolic LVO in hyperacute ischemic stroke, and to develop a preoperative predictive scale for the event.
Source: Journal of the Neurological Sciences - April 28, 2023 Category: Neurology Authors: Kenichi Sakuta, Takeo Sato, Ryoji Nakada, Tomomichi Kitagawa, Hiroki Takatsu, Michiyasu Fuga, Shinji Miyagawa, Teppei Komatsu, Kenichiro Sakai, Hidetaka Mitsumura, Hiroshi Yaguchi, Kenji Okuno, Toshihiro Ishibashi, Yuichi Murayama, Yasuyuki Iguchi Source Type: research

Pleocytosis in cerebrospinal fluid attributed to ischemic stroke: A review of the literature
Lumbar puncture is generally performed in stroke settings when infectious or inflammatory diseases are suspected to be the etiology. This review aimed to assess the prevalence of pleocytosis in the cerebrospinal fluid following ischemic stroke without inflammatory or infectious etiology.
Source: Journal of the Neurological Sciences - April 24, 2023 Category: Neurology Authors: Lucas Ivan Sebastian Rundblad, Helle K. Iversen, Anders S. West Tags: Review Article Source Type: research

Letter to editor: Is improved access to magnetic resonance imaging imperative for optimal ischemic stroke care?
We read the article “Is improved access to magnetic resonance imaging imperative for optimal ischemic stroke care?” [1] with great interest. The authors have presented a concise and informative summary of the use of MRI in ischemic stroke care, emphasizing its significance in diagnosis, management, and secondary pr evention. We appreciate the authors for presenting a comprehensive summary of the use of MRI in ischemic stroke care. However, we have certain points to make about the comparison of the MR scanners provided in this article.
Source: Journal of the Neurological Sciences - March 31, 2023 Category: Neurology Authors: Alex Panther Source Type: research

Computed tomography versus short sequence magnetic resonance imaging in acute ischaemic stroke
It is undisputable that the acute management of stroke requires a fast and accurate diagnostic imaging modality. We read with interest and congratulate Kumar et al. on their article discussing the superiority and benefits of the use of magnetic resonance imaging (MRI) in acute ischaemic stroke (AIS) [1]. The authors suggest that MRI can improve the diagnostic accuracy of computed tomography (CT) negative AIS and allow better selection of patients for reperfusion therapies. Moreover, MRI may help avoid hospital admissions for patients with stroke mimics, facilitate earlier discharge, reduce overall hospital costs and play a...
Source: Journal of the Neurological Sciences - March 30, 2023 Category: Neurology Authors: Ho Lun Wong, Ashraf Nasim, Amit K.J. Mandal, Robert Davies, Constantinos G. Missouris Source Type: research