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Recurrent stroke due to quasi-moyamoya disease associated with POEMS syndrome: An autopsy case
POEMS syndrome, an acronym for polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes, is a fatal disorder associated with plasmacytoma and overproduction of vascular endothelial growth factor (VEGF) [1,2]. Nowadays, a new diagnostic criteria is proposed with high sensitivity and specificity: it demands both three mandatory major criteria (polyneuropathy, monoclonal plasma cell proliferative disorder and elevated VEGF) and at least two of the four minor criteria (oedema/effusion, skin changes, organomegaly and sclerotic bone lesions) [2].
Source: Journal of the Neurological Sciences - February 14, 2020 Category: Neurology Authors: Teruhiko Sekiguchi, Satoru Ishibashi, Jo Sasame, Jun-Ichi Mukae, Kotaro Noda, Hiroaki Tanaka, Koh Yamamoto, Yasunori Takemoto, Jiro Kumagai, Takanori Yokota Tags: Letter to the Editor Source Type: research