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Source: Journal of the Neurological Sciences
Cancer: Macroglobulinemia

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Spinal cord and cranial Bing-Neel Syndrome complicated by cerebral ischemia: A case report
Waldenström's macroglobulinemia (WM) is a B-cell malignancy characterized by lymphoplasmacytic lymphoma (LPL) within the bone marrow and an IgM monoclonal gammopathy in the blood. Symptoms may include weakness or fatigue, anorexia and weight loss, bleeding from the gums and nose, headache, blurred vision, peripheral neuropathy, and even stroke from hyperviscosity. The direct infiltration of the central nervous system (CNS), either as a diffuse leptomeningeal form or tumoral form is an exceedingly rare complication of WM, recognized as Bing-Neel Syndrome (BNS) [1].
Source: Journal of the Neurological Sciences - April 24, 2016 Category: Neurology Authors: Alejandro Vargas, Karan S. Dixit, John G. Quigley, Fernando D. Testai Tags: Letter to the Editor Source Type: research