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Source: Journal of Stroke and Cerebrovascular Diseases
Procedure: Anesthesia
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Total 21 results found since Jan 2013.
General Anesthesia versus Conscious Sedation for the Endovascular Treatment of Acute Ischemic Stroke
The treatment of acute ischemic stroke is characterized by several standard operating principles, which could affect outcome. The first is that the time from stroke onset to the point of reconciliation should be as short as possible because for every 10 minutes without successful reperfusion, approximately 2 million nerve cells die.1 The second guiding principle is that hemodynamic monitoring is key and avoiding hypotension, large blood pressure variation and extremes of blood pressure are important determinants in patient outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - July 8, 2015 Category: Neurology Authors: W. Scott Jellish, Steven B. Edelstein Tags: Editorial Source Type: research
Circulatory and Respiratory Parameters during Acute Endovascular Stroke Therapy in Conscious Sedation or General Anesthesia
Whether patients suffering from acute ischemic stroke and undergoing endovascular recanalization should be treated under general anesthesia (GA) or conscious sedation (CS) is a matter of debate. According to retrospective studies, GA appears to be associated with a worse outcome than CS. The underlying mechanisms are unknown, but hypotension and hypocapnia during GA have been suggested. There are no prospective data on this question.
Source: Journal of Stroke and Cerebrovascular Diseases - April 20, 2015 Category: Neurology Authors: Sibu Mundiyanapurath, Silvia Schönenberger, Maritoni L. Rosales, Ana M. Carrilho Romeiro, Markus Möhlenbruch, Martin Bendszus, Werner Hacke, Julian Bösel Source Type: research
Safety and Hemodynamic Profile of Propofol and Dexmedetomidine Anesthesia during Intra-arterial Acute Stroke Therapy
There is limited data on the safety, hemodynamic profile, and outcome of patients undergoing intra-arterial therapy (IAT) for acute ischemic stroke (AIS) under sedation with dexmedetomidine (DEX) versus propofol (PROP).
Source: Journal of Stroke and Cerebrovascular Diseases - July 28, 2015 Category: Neurology Authors: Seby John, Jaspreet Somal, Umera Thebo, Muhammad S. Hussain, Ehab Farag, Suzanne Dupler, Joao Gomes Source Type: research
Corrigendum to “The SAH Score: A Comprehensive Communication Tool” Journal of Stroke & Cerebrovascular Diseases 23 (2014) 902–909
Neeraj S. Naval, MD,*†‡ Robert G. Kowalski, MBBCh, MS,* Tiffany R. Chang, MD,* Filissa Caserta, MSN, ACNP-BC, CNRN,* J. Ricardo Carhuapoma, MD,*†‡ and Rafael J. Tamargo, MD*‡ From the *Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland; †Department of Anesthesia Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland; and ‡Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Source: Journal of Stroke and Cerebrovascular Diseases - September 1, 2014 Category: Neurology Tags: Corrigendum Source Type: research
Last Electrically Well: Intraoperative Neurophysiological Monitoring for Identification and Triage of Large Vessel Occlusions
Intra-operative stroke (IOS) is associated with poor clinical outcome as detection is often delayed and time of symptom onset or patient's last known well (LKW) is uncertain. Intra-operative neurophysiological monitoring (IONM) is uniquely capable of detecting onset of neurological dysfunction in anesthetized patients, thereby precisely defining time last electrically well (LEW). This novel parameter may aid in the detection of large vessel occlusion (LVO) and prompt treatment with endovascular thrombectomy (EVT).
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2020 Category: Neurology Authors: Katherine M. Anetakis, Jay N. Dolia, Shashvat M. Desai, Jeffrey R. Balzer, Donald J. Crammond, Parthasarathy D. Thirumala, James F. Castellano, Bradley A. Gross, Ashutosh P. Jadhav Source Type: research
In-House Anesthesia and Interventional Radiology Technologist Support Optimize Mechanical Thrombectomy Workflow after Hours
Prior literature suggests after-hours delay leads to poor functional outcomes in stroke patients undergoing thrombectomy. We aimed to evaluate the impact of time of presentation on mechanical thrombectomy (MT) metrics and its association with long-term functional outcome in an Interventional Radiology (IR) suite equipped operating room (OR) setting.
Source: Journal of Stroke and Cerebrovascular Diseases - August 22, 2020 Category: Neurology Authors: Sudeepta Dandapat, Sami Al Kasab, Cynthia B Zevallos, Mudassir Farooqui, Biyue Dai, Darko Quispe-Orozco, Andres Dajles, David Hasan, Edgar A Samaniego, Colin P Derdeyn, Santiago Ortega-Gutierrez Source Type: research
The Effect of Mitochondrial Calcium Uniporter Opener Spermine on Diazoxide against Focal Cerebral Ischemia—Reperfusion Injury in Rats
Conclusions: Our results suggested that diazoxide, which improved neurological deficits and decreased infarct volume and oxidative stress against ischemia–reperfusion injury, is mediated by spermine.
Source: Journal of Stroke and Cerebrovascular Diseases - March 28, 2013 Category: Neurology Authors: Huanli Dong, Shilei Wang, Zongwang Zhang, Ailan Yu, Zhong Liu Tags: Original Articles Source Type: research
Mitochondrial Calcium Uniporter Opener Spermine Attenuates the Cerebral Protection of Diazoxide through Apoptosis in Rats
Conclusions: Results in our study suggested that diazoxide improved neurologic deficits, decreased infarct volume in cortex but not in subcortex, and apoptosis in cortex against ischemia/reperfusion injury is mediated by spermine.
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2013 Category: Neurology Authors: Lei Zhang, Xiujuan Gao, Xin Yuan, Huanli Dong, Zongwang Zhang, Shilei Wang Tags: Original Articles Source Type: research
Local O Balance in Cerebral Ischemia–Reperfusion Improved during Pentobarbital Compared with Isoflurane Anesthesia
Most anesthetics affect cerebral blood flow and metabolism. We compared microregional O2 balance in cerebral ischemia–reperfusion during pentobarbital and isoflurane anesthesia.
Source: Journal of Stroke and Cerebrovascular Diseases - April 10, 2015 Category: Neurology Authors: Oak Z. Chi, Sylviana Barsoum, Kang H. Rah, Xia Liu, Harvey R. Weiss Source Type: research
A Prospective Nonrandomized Study on Carotid Surgery Performed under General Anesthesia without Intraoperative Cerebral Monitoring
The purpose of this study was to assess our experience of carotid surgery habitually performed under general anesthesia without intraoperative intracerebral monitoring, and following a pre-established perioperative protocol, which includes extensive use of an intraoperative shunt (IOS).
Source: Journal of Stroke and Cerebrovascular Diseases - October 19, 2015 Category: Neurology Authors: Francesco De Santis, Cristina Margot Chaves Brait, Cristian Pattaro, Vladimiro Cesareo, Vincenzo Di Cintio Source Type: research
Limb-Shaking Transient Ischemic Attack Induced by Middle Cerebral Artery Dissection after Lung Surgery
We report a case of limb-shaking transient ischemic attack (TIA) caused by a dissection of the middle cerebral artery (MCA) following lung surgery under general anesthesia. An 81-year-old male patient who underwent lobectomy for lung cancer suddenly developed transient shaking movements of the neck and the left upper distal limb on postoperative day 1. On the basis of the double-barrel appearance of the right M1 segment of the MCA, a diagnosis of MCA dissection was made. Physicians should be aware that limb-shaking TIA is sometimes caused by MCA dissection and could be precipitated by any condition, including lung surgery ...
Source: Journal of Stroke and Cerebrovascular Diseases - July 26, 2017 Category: Neurology Authors: Daisuke Taniguchi, Yutaka Oji, Yuji Ueno, Shunki Hirayama, Mariko Fukui, Nobukazu Miyamoto, Kazuo Yamashiro, Ryota Tanaka, Kenji Suzuki, Nobutaka Hattori Tags: Case Studies Source Type: research
Cerebral Neuromonitoring during Carotid Endarterectomy and Impact of Contralateral Internal Carotid Occlusion
The aim of this study was to identify the reliability of carotid artery stump pressure (SP) in predicting the neurologic changes and correlation with contralateral internal carotid artery (ICA) occlusion in patients undergoing eversion carotid endarterectomy (CEA). The optimal method for monitoring cerebral perfusion during CEA, performed under either local or general anesthesia, is still controversial.
Source: Journal of Stroke and Cerebrovascular Diseases - February 4, 2018 Category: Neurology Authors: Davorin Sef, Andrija Skopljanac-Macina, Milan Milosevic, Anita Skrtic, Vinko Vidjak Source Type: research
Improvement in Microregional Oxygen Supply/Consumption Balance and Infarct Size After Cerebral Ischemia-Reperfusion With Inhibition of p70 Ribosomal S6 Kinase (S6K1)
Background: We tested the hypothesis that inhibition of p70 ribosomal S6 kinase (S6K1) would decrease infarct size and improve microregional O2 supply/consumption balance after cerebral ischemia-reperfusion. Methods: This was tested in isoflurane-anesthetized rats with middle cerebral artery blockade for 1 hour and reperfusion for 2 hours with or without PF-4708671 (S6K1 inhibitor, 75 mg/kg, 15 minutes after blockade). Regional cerebral blood flow was determined using a C14-iodoantipyrine autoradiographic technique.
Source: Journal of Stroke and Cerebrovascular Diseases - July 22, 2019 Category: Neurology Authors: Harvey R. Weiss, Scott J. Mellender, Geza K. Kiss, Xia Liu, Oak Z. Chi Source Type: research
Propofol Reduces Inflammatory Brain Injury after Subarachnoid Hemorrhage: Involvement of PI3K/Akt Pathway
Background: Our previous study showed that propofol, one of the widely used anesthetic agents, can attenuate subarachnoid hemorrhage (SAH)-induced early brain injury (EBI) via inhibiting inflammatory and oxidative reaction. However, it is perplexing whether propofol attenuates inflammatory and oxidative reaction through modulating PI3K/Akt pathway. The present study investigated whether PI3K/Akt pathway is involved in propofol's anti-inflammation, antioxidation, and neuroprotection against SAH-induced EBI.
Source: Journal of Stroke and Cerebrovascular Diseases - October 3, 2019 Category: Neurology Authors: Hua-bin Zhang, Xian-kun Tu, Quan Chen, Song-sheng Shi Source Type: research
