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Cerebral Venous Sinus Thrombosis In COVID-19 Infection: A Case Series and Review of the Literature
SARS-CoV-2, the virus responsible for novel Coronavirus (COVID-19) infection, has recently been associated with a myriad of hematologic derangements; in particular, an unusually high incidence of venous thromboembolism has been reported in patients with COVID-19 infection. It is postulated that either the cytokine storm induced by the viral infection or endothelial damage caused by viral binding to the ACE-2 receptor may activate a cascade leading to a hypercoaguable state. Although pulmonary embolism and deep venous thrombosis have been well described in patients with COVID-19 infection, there is a paucity of literature o...
Source: Journal of Stroke and Cerebrovascular Diseases - November 6, 2020 Category: Neurology Authors: Katarina Dakay, Jared Cooper, Jessica Bloomfield, Philip Overby, Stephan A. Mayer, Rolla Nuoman, Ramandeep Sahni, Edwin Gulko, Gurmeen Kaur, Justin Santarelli, Chirag D. Gandhi, Fawaz Al-Mufti Tags: Case Report Source Type: research

Postpartum Atypical Posterior Reversible Encephalopathy Syndrome in a COVID-19 Patient – An Obstetric Emergency
Encephalopathy in COVID-19 has been widely reported with several reports of posterior reversible encephalopathy syndrome (PRES) speculated to be due to an abrupt surge in blood pressure caused by coronavirus disease. Though peripartum posterior reversible encephalopathy syndrome is well recognized, its atypical variant with hemorrhage is uncommon. Peripartum atypical posterior reversible encephalopathy syndrome with COVID-19 requires early recognition and warrants dedicated inter-disciplinary management.
Source: Journal of Stroke and Cerebrovascular Diseases - September 26, 2020 Category: Neurology Authors: Sripadma P.V., Ashish Rai, Chetan Wadhwa Tags: Case Report Source Type: research

The Incidence and Mortality Ratio of Ischemic Cerebrovascular Accidents in Covid-19 Cases: A systematic Review and Meta-Analysis
Coronavirus disease 2019 (COVID-19) is primarily known as a respiratory illness; however, a wide variety of symptoms and complications of the central nervous system (CNS), such as ischemic cerebrovascular accidents (CVA) have been reported. Hereby, we provide a systematic review and a meta-analysis of the literature, investigating the incidence of ischemic CVA and the mortality due to it in the setting of COVID-19.
Source: Journal of Stroke and Cerebrovascular Diseases - December 17, 2020 Category: Neurology Authors: Sina Parsay, Armin Vosoughi, Aytak Khabbaz, Saeed Sadigh-Eteghad Tags: Original Article Source Type: research

Cerebral venous thrombosis following COVID-19 vaccination
We appreciate the literature review by Abdalkader et al.1 to summarize the clinical epidemiology and features of cerebral venous thrombosis (CVT) in patients with coronavirus disease 2019 (COVID-19). Based on the meta-analysis performed by Baldini et al.,2 the estimated proportion of CVT cases among hospitalized patients with COVID-19 was 0.08%; therefore, it is not surprising that COVID-19 associated CVT had not been given much attention compared to the more common deep vein thrombosis and pulmonary embolism events in this patient population.
Source: Journal of Stroke and Cerebrovascular Diseases - May 10, 2021 Category: Neurology Authors: Chia Siang Kow, Syed Shahzad Hasan Tags: Letter to the Editor Source Type: research

Vaccine-Induced Immune Thrombotic Thrombocytopenia with Disseminated Intravascular Coagulation and Death following the ChAdOx1 nCoV-19 Vaccine
We report a fatal case of vaccine-induced immune thrombotic thrombocytopenia (VITT) after receiving the first dose of the ChAdOx1 nCoV-19 vaccine.
Source: Journal of Stroke and Cerebrovascular Diseases - June 22, 2021 Category: Neurology Authors: Yasser Aladdin, Hussein Algahtani, Bader Shirah Tags: Case Report Source Type: research

COVID-19 in a Hemorrhagic Neurovascular Disease, Cerebral Cavernous Malformation.
Novel coronavirus disease 2019 (COVID-19) has caused confirmed infections in more than 30 million Americans by April 2021, and 130 million worldwide, with a case fatality rate of up to 2-10% (https://ourworldindata.org/coronavirus/). It can cause ischemic and hemorrhagic strokes secondary to coagulopathy and endothelial injury.1 These same factors play a role in Cerebral Cavernous Malformation (CCM), a uncommon hemorrhagic neurovascular disease characterized by grossly dilated vascular “caverns” lined by a single layer of dysfunctional endothelium.
Source: Journal of Stroke and Cerebrovascular Diseases - September 7, 2021 Category: Neurology Authors: Abdallah Shkoukani, Abhinav Srinath, Agnieszka Stadnik, Romuald Girard, Robert Shenkar, Adrienne Sheline, Kristen Dahlem, Cornelia Lee, Kelly Flemming, Issam A. Awad Tags: RESEARCH LETTER Source Type: research

Reversible Cerebral Vasoconstriction Syndrome in Patients with Coronavirus Disease: A Multicenter Case Series
: RCVS (Reversible Cerebral Vasoconstrictive Syndrome) is a condition associated with vasoactive agents that alter endothelial function. There is growing evidence that endothelial inflammation contributes to cerebrovascular disease in patients with coronavirus disease 2019 (COVID-19). In our study, we describe the clinical features, risk factors, and outcomes of RCVS in a multicenter case series of patients with COVID-19.
Source: Journal of Stroke and Cerebrovascular Diseases - September 16, 2021 Category: Neurology Authors: Kristine Arandela, Shilpa Samudrala, Mohamad Abdalkader, Pria Anand, Ali Daneshmand, Hormuzdiyar Dasenbrock, Thanh Nguyen, Charlene Ong, Courtney Takahashi, Julie Shulman, Marc Alain Babi, Sanjeev Sivakumar, Neel Shah, Sandip Jain, Samyuktha Anand, Christ Tags: Original article Source Type: research

COVID-19 in a Hemorrhagic Neurovascular Disease, Cerebral Cavernous Malformation
Novel coronavirus disease 2019 (COVID-19) has caused confirmed infections in more than 30 million Americans by April 2021, and 130 million worldwide, with a case fatality rate of up to 2-10% (https://ourworldindata.org/coronavirus/). It can cause ischemic and hemorrhagic strokes secondary to coagulopathy and endothelial injury.1 These same factors play a role in Cerebral Cavernous Malformation (CCM), an uncommon hemorrhagic neurovascular disease characterized by grossly dilated vascular “caverns” lined by a single layer of dysfunctional endothelium.
Source: Journal of Stroke and Cerebrovascular Diseases - September 7, 2021 Category: Neurology Authors: Abdallah Shkoukani, Abhinav Srinath, Agnieszka Stadnik, Romuald Girard, Robert Shenkar, Adrienne Sheline, Kristen Dahlem, Cornelia Lee, Kelly Flemming, Issam A. Awad Tags: Short Communication Source Type: research

Hypercoagulability of COVID-19 and Neurological Complications: A Review
The SARS-CoV-2 virus, which causes Coronavirus disease 2019 (COVID-19), has resulted in millions of worldwide deaths. When the SARS-CoV-2 virus emerged from Wuhan, China in December 2019, reports of patients with COVID-19 revealed that hospitalized patients had acute changes in mental status, cognition, and encephalopathy. Neurologic complications can be a consequence from overall severity of the systemic infection, direct viral invasion of the SARS-CoV-2 virus in the central nervous system, and possible immune mediated mechanisms.
Source: Journal of Stroke and Cerebrovascular Diseases - October 26, 2021 Category: Neurology Authors: Patrick Moore, Fatema Esmail, Shuai Qin, Sucha Nand, Stephanie Berg Tags: Review Article Source Type: research

Cerebrovascular involvement in mucormycosis in COVID-19 pandemic
We describe clinico-radiological manifestations of cerebrovascular complications observed in CAM.
Source: Journal of Stroke and Cerebrovascular Diseases - November 21, 2021 Category: Neurology Authors: Rahul Kulkarni, Shripad S Pujari, Dulari Gupta, Pawn Ojha, Megha Dhamne, Vyankatesh Bolegave, Pramod Dhonde, Anand Soni, Sikandar Adwani, Anand Diwan, Dhananjay Duberkar, Dhruv Batra, Rushikesh Deshpande, Kaustubh Aurangabadkar, Nilesh Palasdeokar Source Type: research

Management and outcomes of COVID – 19 associated Cerebral Venous Sinus Thrombosis
Systemic hyper-coagulabilty leading to micro and macro thrombosis is a known complication of Coronavirus disease – 2019(COVID -19). The postulated mechanism appears to be the viral activation of endothelium, triggering the coagulation pathways. Thrombosis of the cerebral veins and sinuses (CVT), a potentially serious condition, has been increasingly reported with COVID – 19 infection. In this clinical stud y we attempt to describe the clinical profile, investigations and outcomes of patients with COVID- 19 associated CVT.
Source: Journal of Stroke and Cerebrovascular Diseases - January 9, 2022 Category: Neurology Authors: Miraclin T Angel, Sanjith Aaron, Ajith Sivadasan, Kenneth Benjamin, Vanjare Harshad, Shalini Nair, KPP Abhilash, Prabhakar AT, Vivek Mathew Source Type: research

Isolated and Combined Unilateral Central Retinal Artery and Vein Occlusions After Vaccination. A Review of the Literature
Retinal artery occlusion (RAO), especially central RAO, is a sight-threatening and potentially blinding ophthalmic emergency. Recent publications reported its association with coronavirus disease 2019 (COVID-19) mRNA vaccines. Although rare, vaccines have been linked to ophthalmic complications, and it is of interest to examine the current literature on vaccine-related RAO.
Source: Journal of Stroke and Cerebrovascular Diseases - May 12, 2022 Category: Neurology Authors: Clarice, Kai-ying Su, Sunny, Chi Lik Au Tags: Short Communication Source Type: research

Is a high chest CT severity score a risk factor for an increased incidence of long-term neuroimaging findings after COVID-19?
From the outbreak of the Coronavirus disease 2019 (COVID-19) pandemic on 17 November 2019 in Wuhan to 2 November 2022, the total number of cases was reported as 617,879,854 and the total number of deaths was reported as 6,546,448 worldwide 1. In Turkey, the first case was reported on March 11, 2020. Until November 2, 2022, the total number of cases was 16,873,793 and the total number of deaths was 101,139 1. Today, there is a significant decrease in the number of cases and deaths as a result of vaccination and mutations in the virus.
Source: Journal of Stroke and Cerebrovascular Diseases - November 29, 2022 Category: Neurology Authors: Ahmet-Turan Kaya, Burcu Akman Source Type: research

A neonatal case of cerebral venous thrombosis with intrauterine onset after COVID19 infection during pregnancy: cause or coincidence?
Coronavirus 19 disease (COVID-19) is known to predispose patients to increased thrombotic events and the risk is higher in pregnancy which is already a hypercoagulable state. Vertical transmission of the disease during pregnancy was neglected according to data early in the pandemic, however, despite conflicting results from different studies, there is an increasing suspicion of vertical transmission with the rise of new fetal and neonatal cases and perinatal transmission can be higher than expected.
Source: Journal of Stroke and Cerebrovascular Diseases - December 1, 2022 Category: Neurology Authors: Mine Ozdil, İpek Dokurel Cetin Tags: Case Report Source Type: research

A neonatal case of cerebral venous sinus thrombosis with intrauterine onset after COVID-19 infection during pregnancy: Cause or coincidence?
Coronavirus 19 disease (COVID-19) is known to predispose patients to increased thrombotic events and the risk is higher in pregnancy which is already a hypercoagulable state. Vertical transmission of the disease during pregnancy was neglected according to data early in the pandemic, however, despite conflicting results from different studies, there is an increasing suspicion of vertical transmission with the rise of new fetal and neonatal cases and perinatal transmission can be higher than expected.
Source: Journal of Stroke and Cerebrovascular Diseases - December 1, 2022 Category: Neurology Authors: Mine Ozdil, Ipek Dokurel Cetin Tags: Case Report Source Type: research

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