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Impact of the coronavirus disease pandemic on the number of strokes and mechanical thrombectomies: A systematic review and meta-analysis
This systematic review and meta-analysis aimed to evaluate the impact of the coronavirus disease (COVID-19) pandemic on stroke care, including the number of stroke alerts/codes, number of reperfusions, and number of thrombectomies during the pandemic compared to those during the pre-pandemic period.
Source: Journal of Stroke and Cerebrovascular Diseases - July 21, 2020 Category: Neurology Authors: Julius July, Raymond Pranata Source Type: research

Malignant Cerebral Ischemia in A COVID-19 Infected Patient: Case Review and Histopathological Findings
Severe acute respiratory syndrome coronavirus (SARS-CoV-2) is responsible for an unprecedented worldwide pandemic that has severely impacted the United States. As the pandemic continues, a growing body of evidence suggests that infected patients may develop significant coagulopathy with resultant thromboembolic complications including deep vein thrombosis, pulmonary embolism, myocardial infarction, and ischemic stroke. However, this data is limited and comes from recent small case series and observational studies on stroke types, mechanisms, and outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - August 4, 2020 Category: Neurology Authors: Smit D. Patel, Ryan Kollar, Patrick Troy, Xianyuan Song, Mohammad Khaled, Augusto Parra, Mubashir Pervez Source Type: research

Letter to the Editor Regarding ‘A neonatal case of cerebral venous sinus thrombosis with intrauterine onset after COVID19 infection during pregnancy: cause or coincidence?’
We read with interest the article by Ozdil et al. about a three day-old female neonate who was diagnosed with venous sinus thrombosis (VST) which was complicated by a subacute, partial ischemic stroke in the territory of the right middle cerebral artery.1 The age of the stroke was estimated at 14-28 days before birth.1 Because the mother suffered a mild coronvirus disease-19 (COVID-19) infection during the initial weeks of the third trimester (gestational weeks 27-30), VST in the fetus was causally related to the severe, acute respiratory syndrome-coronavirus type-2 (SARS-CoV-2) infection of the mother.
Source: Journal of Stroke and Cerebrovascular Diseases - April 7, 2023 Category: Neurology Authors: Josef Finsterer Tags: Letter to the Editor Source Type: research

Coronavirus Disease 2019 and Stroke: Clinical Manifestations and Pathophysiological Insights
An outbreak of an acute respiratory illness of unknown cause started in Wuhan, Hubei province, China on December 12, 2019.1,2 A new strain of coronavirus, named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was identified in these patients. Subsequently, the identified acute respiratory illness was named coronavirus disease 2019 (COVID-19). Soon thereafter, the COVID-19 epidemic in China became a pandemic with a significant burden on healthcare and the world-wide economy. SARS-CoV-2 has been shown to be a distinct class of the beta coronaviruses (Beta-CoVs) with a 79.5% gene sequence homology to the severe ...
Source: Journal of Stroke and Cerebrovascular Diseases - May 10, 2020 Category: Neurology Authors: Afshin A. Divani, Sasan Andalib, Mario Di Napoli, Simona Lattanzi, M. Shazam Hussain, Jos é Biller, Louise D. McCullough, M. Reza Azarpazhooh, Alina Seletska, Stephan A. Mayer, Michel Torbey Tags: Review Article Source Type: research

Thalamic perforating artery stroke on computed tomography perfusion in a patient with coronavirus disease 2019
We present a case illustrating the value of CT perfusion to identify acute small subcortical infarcts in a patient with COVID-19 admitted to an intensive care unit for bilateral pneumonia and pulmonary embolism presenting with sudden right limb weakness.
Source: Journal of Stroke and Cerebrovascular Diseases - May 20, 2020 Category: Neurology Authors: Salvatore Rudilosso, Diana Esteller, Xabier Urra, Ángel Chamorro Tags: Case Report Source Type: research

Reversible Cerebral Vasoconstriction Syndrome and Dissection in the Setting of COVID-19 Infection
The current COVID-19 pandemic has recently brought to attention the myriad of neuro- logic sequelae associated with Coronavirus infection including the predilection for stroke, particularly in young patients. Reversible cerebral vasoconstriction syndrome (RCVS) is a well-described clinical syndrome leading to vasoconstriction in the intracra- nial vessels, and has been associated with convexity subarachnoid hemorrhage and oc- casionally cervical artery dissection. It is usually reported in the context of a trigger such as medications, recreational drugs, or the postpartum state; however, it has not been described in COVID-19 infection.
Source: Journal of Stroke and Cerebrovascular Diseases - June 4, 2020 Category: Neurology Authors: Katarina Dakay, Gurmeen Kaur, Edwin Gulko, Justin Santarelli, Christian Bowers, Stephan A Mayer, Chirag D Gandhi, Fawaz Al-Mufti Tags: Case Report Source Type: research

Posterior Reversible Encephalopathy Syndrome in Patients with Coronavirus Disease 2019: Two Cases and a Review of the Literature
Central nervous system (CNS) manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection include encephalopathy, encephalitis, meningitis, acute disseminated encephalomyelitis, and stroke [1], both as a result of direct viral invasion of the central nervous system [2 –5] and as a consequence of critical illness and systemic infection [6]. Coronavirus disease 2019 (COVID-19) may also cause significant changes in endothelial morphology, including disruption of intercellular junctions, cell swelling, and a loss of contact with the basal membrane [7].
Source: Journal of Stroke and Cerebrovascular Diseases - July 29, 2020 Category: Neurology Authors: Pria Anand, K. H.Vincent Lau, David Y Chung, Deepti Virmani, Anna M. Cervantes-Arslanian, Asim Mian, Courtney E. Takahashi Source Type: research

Large vessel occlusion secondary to COVID-19 hypercoagulability in a young patient: A Case Report and Literature Review
We report a case of 33-year-old African American woman with COVID-19 who developed acute malignant middle cerebral artery infarction due to thromboembolic occlusion of the left terminal internal carotid artery and middle cerebral artery stem. Mechanical thrombectomy was challenging and ultimately unsuccessful resulting in limited reperfusion of
Source: Journal of Stroke and Cerebrovascular Diseases - September 9, 2020 Category: Neurology Authors: Thomas John Pisano, Ian Hakkinen, Igor Rybinnik Source Type: research

Transcranial Doppler Ultrasound Evidence of Active Cerebral Embolization in COVID-19
: To report six consecutive patients with confirmed coronavirus disease-2019 (COVID-19) who underwent Transcranial Doppler (TCD) ultrasonography evaluation for cerebral microemboli in the setting of suspected or confirmed acute ischemic stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - December 9, 2020 Category: Neurology Authors: Ayush Batra, Jeffrey R. Clark, Katie LaHaye, Nathan A. Shlobin, Steven C. Hoffman, Zachary S. Orban, Katharine Colton, Jane E. Dematte, Farzaneh A. Sorond, Igor J. Koralnik, Eric M. Liotta Source Type: research

Coronavirus Positive Patients Presenting with Stroke-Like Symptoms
Several studies from Wuhan, China have reported neurological manifestations in patients who tested positive for coronavirus disease 2019 (COVID-19). One study reported 214 COVID-19 positive patients, out of which 41.1% had severe infection. 5.7% of patients with severe infection had acute cerebrovascular disease1. Another study looked at 221 COVID-19 positive patients, out of which 5% had ischemic infarcts and 0.5% had cerebral hemorrhage2. A recent study from Mount Sinai Hospital in New York reported five cases of cerebral infarcts due to large vessel occlusion in patients who tested positive for COVID-19.
Source: Journal of Stroke and Cerebrovascular Diseases - January 9, 2021 Category: Neurology Authors: Shaista Alam, Robin N. Dharia, Elan Miller, Fred Rincon, Diana L. Tzeng, Rodney D. Bell Source Type: research

Response to the Letter to the Editor: Consideration Needed for Early Anticoagulation Following Intravenous tPA in Patients with COVID-19
We thank Dr. Angelo Jimenez and his colleagues for their letter to the editor regarding our report of a multicenter series of patients with coronavirus disease 2019 (COVID-19) who received intravenous (IV) tissue plasminogen activator (tPA) for suspected acute ischemic stroke. Their letter emphasizes the important contribution of a hypercoagulable state in patients with COVID-19.
Source: Journal of Stroke and Cerebrovascular Diseases - March 29, 2021 Category: Neurology Authors: Thiago Carneiro, Jonathan Dashkoff, Lester Leung, Christa O'Hana S. Nobleza, Erika Marulanda-Londono, Mausaminben Hathidara, Sebastian Koch, Nicole Sur, Alexandra Boske, Barbara Voetsch, Ali Daneshmand, Julie Shulman, Giaocchino Curiale, David M. Greer, J Source Type: research

Response to Letter to the Editor
This is in response to the question asked by the author of the manuscript entitled “Comments on Coronavirus Positive Patients Presenting with Stroke-Like Symptoms”.
Source: Journal of Stroke and Cerebrovascular Diseases - May 4, 2021 Category: Neurology Authors: Shaista Alam Source Type: research

Racial Disparities in Ischemic Stroke among Patients with COVID-19 in the United States
Cerebrovascular prevalence is high in patients with coronavirus disease 2019 (COVID-19). However, whether racial disparities exist among this population have not been systematically explored.
Source: Journal of Stroke and Cerebrovascular Diseases - May 18, 2021 Category: Neurology Authors: Alain Lekoubou, Matt Pelton, Djibril M. Ba, Addy Ssentongo Source Type: research

Impact of coronavirus disease 2019 on time delay and functional outcome of mechanical thrombectomy in Tokyo, Japan
Several papers from around the world have reported that outbreaks of coronavirus disease 2019 (COVID-19) have led to the following time delays associated with endovascular mechanical thrombectomy (MT) for patients with acute ischemic stroke (AIS): onset-to-door (O2D) time,1,2 door-to-puncture (D2P) time and door-to-recanalization time.3 Several speculative factors may explain these delays, such as a collapse of emergency services focused on patients with COVID-192 and patients ’ fear of exposure to COVID-19 through interactions within the health-care system.
Source: Journal of Stroke and Cerebrovascular Diseases - August 12, 2021 Category: Neurology Authors: Masahiro Katsumata, Takahiro Ota, Junya Kaneko, Hiroyuki Jimbo, Rie Aoki, Shigeta Fujitani, Masahiko Ichijo, Masato Inoue, Keigo Shigeta, Yoshifumi Miyauchi, Yu Sakai, Hideki Arakawa, Yoshinobu Otsuka, Kenichi Ariyada, Yoshiaki Kuroshima, Takahisa Fuse, Y Source Type: research

Patent Foramen Ovale related cryptogenic stroke during COVID-19 disease in three patients: a case series
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), termed COVID-19, first detected in Whuan, was officially declared a pandemic by the World Health Organization on March 11, 2020. The epidemic of COVID-19 has rapidly spread worldwide. Italy was the first European country to be affected and, currently, Italy has reported 4,343,397 COVID-19-positive cases (1).
Source: Journal of Stroke and Cerebrovascular Diseases - September 13, 2021 Category: Neurology Authors: Daniela Palleri, Marta Guidarini, Elisabetta Mariucci, Anna Balducci, Gabriele Egidy Assenza, Susanna Esposito, Andrea Donti Source Type: research

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