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Validity of stroke severity assessment using medical records in a population-based cohort
Initial stroke severity is an important prognostic factor for outcome after acute stroke, in terms of functional dependency, post-stroke dementia, and mortality.1,2 Whilst the majority of stroke patients who are admitted to the hospital with stroke have substantial neurological deficits, over half of all strokes that occur in the population qualify as minor stroke,3 and are managed often in outpatient care.4 Given the important differences between minor and major stroke in prognosis and management, it is important to distinguish patients on the basis of stroke severity, but assessment outside of specialised stroke centres ...
Source: Journal of Stroke and Cerebrovascular Diseases - February 18, 2023 Category: Neurology Authors: Jacqueline J. Claus, Brian B.P. Berghout, M. Kamran Ikram, Frank J. Wolters Source Type: research

The Spectrum of Aphasia Subtypes and Etiology in Subacute Stroke
Background: Aphasia is one of the most common stroke syndrome presentations, yet little is known about the spectrum of different subtypes or their stroke mechanisms. Yet, subtypes and etiology are known to influence the prognosis and recovery.Aim: Our aim is to analyze aphasia subtypes and etiology in a large subacute stroke population.Methods: Consecutive patients from a dedicated cognitive stroke registry were accrued. A validated cognitive screening examination was administered during the first month of stroke presentation, which enabled a diagnosis of 14 different aphasic subtypes. The evolution from one subtype to ano...
Source: Journal of Stroke and Cerebrovascular Diseases - May 15, 2013 Category: Neurology Authors: Michael Hoffmann, Ren Chen Tags: Original Articles Source Type: research

Trends in cognitive function assessed by a battery of neuropsychological tests after mild acute ischemic stroke
Cognitive impairment is common after stroke. Most acute ischemic stroke (AIS) patients show cognitive decline in neuropsychological assessments in the early phase of stroke.1,2 Post-stroke cognitive impairment (PSCI) is a broad concept that has been used to define cognitive decline, fulfilling established criteria for cognitive impairment within the first six months following a stroke, which includes post-stroke dementia (PSD) and post-stroke cognitive impairment no dementia (PSCIND).3 Previous studies demonstrated that up to 90% of patients with ischemic stroke had cognitive dysfunction on detailed tests in the acute periods.
Source: Journal of Stroke and Cerebrovascular Diseases - May 9, 2020 Category: Neurology Authors: Yi-Ming Yang, Zhong-Min Zhao, Wei Wang, Fang-Ming Dong, Pan-Pan Wang, Yang-Juan Jia, Ning Han, Yan-Li Jia, Jian-Hua Wang Source Type: research

Hyponatremia in the Prognosis of Acute Ischemic Stroke
Background: Hyponatremia is a risk factor for stroke and cardiovascular disease. Even mild hyponatremia is associated with increased 30-day mortality after myocardial infarction, and it has recently shown to increase the 3-year mortality after a stroke. In this work, we investigated both acute and chronic clinical outcomes after a stroke in hyponatremic patients.Methods: We reviewed all patients admitted between 2004 and 2011 with the diagnosis of acute ischemic stroke. Hyponatremia was defined as serum sodium level less than 135 mmol/L and recorded on admission. All hemorrhagic strokes were excluded. Data were analyzed us...
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2013 Category: Neurology Authors: Bernardo Rodrigues, Ilene Staff, Gilbert Fortunato, Louise D. McCullough Tags: Original Articles Source Type: research

Informing Patients with Acute Stroke About their Risk of Dementia: A Survey of UK Healthcare Professionals
People who have a stroke are at an increased risk of developing dementia.1,2 According to the 2021 James Lind Alliance –Stroke Association Priority Setting Partnership, cognitive issues after stroke are a key concern of people who have a stroke.3 Identifying which patients with acute stroke are at risk of dementia could help patients and their carers to plan for the future. However, informing a patient who has jus t had a stroke about their risk of dementia may cause anxiety.
Source: Journal of Stroke and Cerebrovascular Diseases - January 12, 2022 Category: Neurology Authors: Emily L. Ball, Gillian E. Mead, Eugene Y.H. Tang, Dorota Religa, Terence J. Quinn, Susan D. Shenkin Source Type: research

Incidence and risk factors of vascular dementia in Thai stroke patients
Stroke is one of the most common causes of disability worldwide. Besides physical disability in stroke survivors, vascular cognitive impairment (VCI) can prevent the patients from living independently. VCI or cognitive impairment from cerebrovascular disease is the second most common cause of dementia.1 VCI can follow ‘clinical’ stroke or occur in patients with no history of stroke. Those without history of clinical stroke should have sufficient cerebrovascular disease lesions detected by neuroimaging to cause cognitive impairment.
Source: Journal of Stroke and Cerebrovascular Diseases - May 13, 2020 Category: Neurology Authors: Pornpatr A. Dharmasaroja, Chanin Limwongse, Thammanard Charernboon Source Type: research

Analyzing Cost-Effectiveness of Allocating Neurointerventionist for Drive and Retrieve System for Patients with Acute Ischemic Stroke
The cost of stroke treatment accounts for approximately 6% of Japan's national medical expenditure,1 and stroke is the second most common condition, after dementia, that results in a requirement for long-term care. Thus, stroke has a significant impact on society.2 Cerebral infarction accounts for 60% or more of stroke cases.3 Systematic provision of highly equitable and efficient treatment for cerebral infarction is an important policy issue, such as the enactment of the Stroke and Cardiovascular Disease Control Act in December 2018 in Japan, as part of an effort to enhance provision of treatment for cerebral infarction.
Source: Journal of Stroke and Cerebrovascular Diseases - May 14, 2021 Category: Neurology Authors: Yasuhiro Morii, Toshiya Osanai, Kensuke Fujiwara, Takumi Tanikawa, Kiyohiro Houkin, Songzi Gu, Katsuhiko Ogasawara Source Type: research

Alteration in brain functional connectivity in patients with post-stroke cognitive impairment during memory task: A fNIRS study
Post-stroke cognitive impairment (PSCI) refers to a spectrum of cognitive deterioration following stroke, ranging from mild cognitive impairment to dementia. Cortical plastic alterations associated with post-stroke cognitive impairment are not well documented. It is universally acknowledged as a prevalent and severe clinical syndrome that has an adverse influence on the prognosis of stroke patients [1]. Although PSCI is an umbrella term for a variety of pathological conditions, memory, and cognition impairments are the most troubling for stroke survivors and their carers [2].
Source: Journal of Stroke and Cerebrovascular Diseases - July 29, 2023 Category: Neurology Authors: Ying Kong, Wenna Peng, Jing Li, Chunjiao Zhu, Changjie Zhang, Yongmei Fan Source Type: research

Prestroke Dementia is Associated With Poor Outcomes After Reperfusion Therapy Among Elderly Stroke Patients
Conclusions: Among the elderly, prestroke dementia is a powerful independent predictor of in-hospital mortality after acute reperfusion therapy for stroke. Future investigations of thrombolysis outcomes in the elderly are warranted.
Source: Journal of Stroke and Cerebrovascular Diseases - December 19, 2011 Category: Neurology Authors: Katharina M. Busl, Raul G. Nogueira, Albert J. Yoo, Joshua A. Hirsch, Lee H. Schwamm, Natalia S. Rost Tags: Original Articles Source Type: research

Cognitive Dysfunction in Stroke Survivors: A Community-Based Prospective Study from Kolkata, India
The frequency of cognitive dysfunction among community stroke survivors (SS) is not known in India. This prospective study investigated the prevalence of poststroke mild cognitive impairment (psMCI) and poststroke dementia (psDem), the annual progression rate to dementia, and pertinent risk factors in a sample population of SS in Kolkata, India between September 2006 and July 2010. From a community-based stroke registry, 281 SS were assessed at baseline year after excluding attrition due to various causes. Validated cognitive tools were applied by trained field workers under supervision of a neuropsychologist. The assessme...
Source: Journal of Stroke and Cerebrovascular Diseases - June 21, 2012 Category: Neurology Authors: Sujata Das, Neelanjana Paul, Avijit Hazra, Malay Ghosal, Biman Kanti Ray, Tapas Kumar Banerjee, Prabir Burman, Shyamal Kumar Das Tags: Original Articles Source Type: research

Design and Rationale for a Cognitive Outcome Substudy in Ischemic Stroke Patients with High Risk of Cerebral Hemorrhage
Cognitive impairment and dementia are common disabilities after stroke and are associated with increased risks of mortality and recurrent stroke. The prevention of dementia and preserving cognitive function are also important in stroke patients, but its strategy is not established yet. This PICASSO-COG (PreventIon of CArdiovascular events in iSchemic Stroke patients with high risk of cerebral hemOrrhage for reducing COGnitive decline) substudy aims to assess the effects of cilostazol and/or probucol on cognitive function.
Source: Journal of Stroke and Cerebrovascular Diseases - May 31, 2016 Category: Neurology Authors: Kyung-Ho Yu, Keun-Sik Hong, Mi-Sun Oh, Juneyoung Lee, Ji Sung Lee, Sun U. Kwon, PICASSO investigators Source Type: research

Association of Blood Pressure and Cognition after Stroke
We examined associations between systolic and diastolic BP (SBP, DBP), pulse pressure (PP), mean arterial pressure (MAP), and cognition, each measured 90 days after stroke. Methods: Cross-sectional analysis of prospectively obtained data of 432 dementia-free subjects greater than or equal to 45 (median age, 66; 45% female) with stroke (92% ischemic; median NIH stroke score, 3 [IQR, 2-6]) from the population-based Brain Attack Surveillance in Corpus Christi (BASIC) project in 2011-2013.
Source: Journal of Stroke and Cerebrovascular Diseases - May 2, 2020 Category: Neurology Authors: Deborah A. Levine, Andrzej T. Galecki, Dolorence Okullo, Emily M. Brice ño, Mohammed U. Kabeto, Lewis B. Morgenstern, Kenneth M. Langa, Bruno Giordani, Robert Brook, Brisa N. Sanchez, Lynda D. Lisabeth Source Type: research

Association Between Oral Anticoagulants and Stroke Severity at Onset in Elderly Patients with Cardioembolic Stroke Due to Non-Valvular Atrial Fibrillation
The prevention of cardioembolic stroke is an important public health priority in Japan due to its high prevalence in elderly individuals. Compared to their younger counterparts, elderly patients with cardioembolic stroke are more likely to have multiple comorbidities, a higher risk of serious complications, such as pneumonia and heart failure, and cognitive impairments (e.g., dementia or delirium), which may adversely affect their ability to participate in active rehabilitation. These factors negatively affect clinical outcomes, and many elderly stroke survivors require long-term care despite the early implementation of intensive therapy.
Source: Journal of Stroke and Cerebrovascular Diseases - December 25, 2021 Category: Neurology Authors: Ichiro Deguchi, Takashi Osada, Shinichi Takahashi Source Type: research

Time Trends and Characteristics of Prevalent Dementia among Patients Hospitalized for Stroke in the United States
Little is known about how prevalent dementia rates among patients with stroke have evolved over the last decade or how this relationship varies by gender, race ethnicity, stroke type, or dementia type. We assessed time trends and demographic predictors of coexisting dementia in a large cohort of patients hospitalized for stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - March 14, 2018 Category: Neurology Authors: Ayesha Sherzai, Bruce Ovbiagele, Dean Sherzai Source Type: research

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