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Healthcare expenditure trends among adult stroke patients in the United States, 2011-2020
In the US, between 2018 and 2019, approximately $57 billion were expended on stroke and related conditions. The aim of this study was to understand trends in direct healthcare expenditures among stroke patients using novel cost estimation methods and a nationally representative database.
Source: Journal of Stroke and Cerebrovascular Diseases - August 31, 2023 Category: Neurology Authors: Venkataraghavan Ramamoorthy, Kelvin Chan, Mukesh Roy, Anshul Saxena, Md Ashfaq Ahmed, Zhenwei Zhang, Sandeep Appunni, Ronnie Thomas, Peter McGranaghan, Michael McDermott, Felipe De Los Rios La Rosa, Muni Rubens Source Type: research

Post-stroke pneumonia: Factors associated with readmission within 90 days of stroke discharge
Stroke is the fifth leading cause of death and a leading cause of disability within the United States.1,2 On average, a stroke occurs every 40 seconds and accounts for approximately 1 in every 19 deaths.2 The prevalence of stroke is projected to increase by 20.5% from 2012 to 2030.2 Post-stroke complications are prevalent; infection occurs among 30% of acute cases.3 Pneumonia is one of the most common post-stroke infections and is associated with increased morbidity.4,5 Moreover, pneumonia is recognized as an independent risk factor for stroke-related mortality.
Source: Journal of Stroke and Cerebrovascular Diseases - August 21, 2023 Category: Neurology Authors: Tiffany Bouddhara, LeighAnn Persondek, Elizabeth Ablah, Hayrettin Okut, Liuqiang Lu, James Walker Source Type: research

Risk of suicide among stroke survivors in the United States
Stroke is the largest cause of disability and the 5th leading cause of death in the United States. Suicide is the 12th leading cause of death in the United States. However, little is known about the risk of suicide among people with a prior stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2023 Category: Neurology Authors: Ben Grobman, Neeharika Kothapalli, Arian Mansur, Christine Y Lu Source Type: research

Prevalence and predictors of low folate levels among stroke survivors in a country without mandatory folate food fortification: Analysis of a Ghanaian sample
Vitamin supplementation with folic acid (FA) reduces hyperhomocysteinemia (Hcy), a vascular risk factor with a strong, graded, and independent association with stroke and other vascular diseases.1 Available data suggest that a 25% reduction in total plasma homocysteine level is accompanied by a 19% lower stroke risk.1,2 Evidence from clinical trials on the effect of folate supplementation on mitigation of stroke risk has however been conflicting. A synthesis of clinical trial data has shown that supplemental FA had a neutral effect on reducing vascular events in countries with a mandate for folate fortification of food, fo...
Source: Journal of Stroke and Cerebrovascular Diseases - July 20, 2023 Category: Neurology Authors: Fred Stephen Sarfo, Richard Boateng, Priscilla Abrafi Opare-Addo, Rexford Adu Gyamfi, Samuel Blay Nguah, Bruce Ovbiagele Source Type: research

Body mass index and waist circumference as predictors of recurrent vascular events after a recent ischemic stroke
Obesity is an independent contributor to ischemic stroke incidence. A meta-analysis of 13 studies revealed that a 5 kg/m2 increase in body mass index (BMI) was associated with a 22% increased risk of ischemic stroke in European/North American/Australian cohorts and a 35% increased risk of ischemic stroke among the Asian populations.1 In a meta-analysis of 7 prospective studies, persons in the highest waist circumference (WC) category had a relative risk of 1.41 (95% CI, 1.21 ⁠–1.56) for ischemic stroke compared with persons in the lowest category.
Source: Journal of Stroke and Cerebrovascular Diseases - July 11, 2023 Category: Neurology Authors: Kyusik Kang, Jong-Moo Park, Wi-Sun Ryu, Sang-Wuk Jeong, Dong-Eog Kim, Hong-Kyun Park, Yong-Jin Cho, Keun-Sik Hong, Kyung Bok Lee, Tai Hwan Park, Sang-Soon Park, Juneyoung Lee, Beom Joon Kim, Moon-Ku Han, Hee-Joon Bae Source Type: research

Hospital Discharge and Readmissions Before and During the COVID-19 Pandemic for California Acute Stroke Inpatients
Stroke is a leading cause of death and disability in the United States, with approximately 795,000 new strokes occurring annually, including acute ischemic stroke (AIS), intracerebral hemorrhage (ICH), and subarachnoid hemorrhage (SAH).1 The Coronavirus Disease 2019 (COVID-19) pandemic has impacted all levels of care for stroke patients, such as delays in initial presentation, reduction in acute therapies, limitations of in-patient resources, delays or lack of initiation of secondary stroke prevention therapy, and limitations in rehabilitation services after hospital discharge.
Source: Journal of Stroke and Cerebrovascular Diseases - June 23, 2023 Category: Neurology Authors: George P. Albert, Daryl C. McHugh, Debra E. Roberts, Adam G. Kelly, Remi Okwechime, Robert G. Holloway, Benjamin P. George Source Type: research

Association of serum uric acid with risk of stroke in US adults: A cross-sectional study from NHANES 1999 –2020
Stroke is the second-most global death cause, only after ischemic heart disease, and third-most contributor to disability1, making it a major therapeutic challenge. More than 100 million individuals worldwide experience stroke every year, of which 795,000 cases are in the United States.2 Therefore, improved preventive strategies are needed; particularly, strategies targeting the modifiable risk factors of stroke, such as hypertension, hyperglycemia, and dyslipidemia, may help prevent more than approximately 90% of stroke cases.
Source: Journal of Stroke and Cerebrovascular Diseases - June 3, 2023 Category: Neurology Authors: Bei Gao, Yun Bao, Min Meng, Lijun Yu, Yali Lu, Rina Sa, Xiaoyan Liang, Jie Shi Source Type: research

Intra-arterial thrombolysis as adjunct to mechanical thrombectomy in acute ischemic stroke patients in the United States: A case control analysis
Although observational studies have reported favorable clinical outcomes associated with intra-arterial thrombolysis as adjunct to mechanical thrombectomy, the cost and length of hospitalization associated with this intervention has not been studied.
Source: Journal of Stroke and Cerebrovascular Diseases - May 5, 2023 Category: Neurology Authors: Chun Shing Kwok, Navpreet K. Bains, Daniel E. Ford, Camilo R. Gomez, Daniel F. Hanley, Ameer E. Hassan, Thanh N. Nguyen, Farhan Siddiq, Alejandro M. Spiotta, Syed F. Zaidi, Adnan I. Qureshi Source Type: research

Mechanisms of in-hospital acute ischemic stroke and their relevance to prognosis: A retrospective analysis
In-hospital stroke (IHS) refers to stroke that occurs during hospitalization in patients admitted for other diagnoses,1 of which ischemic stroke is the most common type, accounting for approximately 60% to 89%.2,3 IHS is common with approximately 35,000 to 75,000 patients having a stroke while hospitalized in the United States each year.4 The incidence of IHS tends to increase per year,5 resulting in a serious social burden. In-hospital ischemic strokes are widely distributed across various in-hospital departments.
Source: Journal of Stroke and Cerebrovascular Diseases - April 11, 2023 Category: Neurology Authors: Juanjuan Wu, Guangsong Han, Yuhui Sha, Mingyu Tang, Ziang Pan, Ziyue Liu, Yicheng Zhu, Lixin Zhou, Jun Ni Source Type: research

Household income is associated with functional outcomes in a multi-institutional cohort of patients with ischemic stroke and COVID-19
We examined whether household income is associated with functional outcomes after stroke and COVID-19.
Source: Journal of Stroke and Cerebrovascular Diseases - February 19, 2023 Category: Neurology Authors: Brian Stamm, Regina Royan, Gabriela Trifan, Ronald Alvaredo-Dyer, Faddi G. Saleh Velez, William Taylor, Pranusha Pinna, Nicholas J. Reish, Alejandro Vargas, Fernando D. Goldenberg, Michael J Schneck, Jos é Biller, Fernando Testai, Fan Z. Caprio, Sherry H Source Type: research

Effects of virtual reality-based telerehabilitation for stroke patients: A systematic review and meta-analysis of randomized controlled trials
Stroke is a severe neurological disorder that occurs in nearly 800,000 people and kills more than 140,000 people per year in the United States.1 The cost of stroke is projected to rise to $231 billion by the year 2030.2 Moreover, stroke is the leading cause of serious long-term disability.1 These stroke survivors suffer from a variety of impairments, including motor, sensory, speech, cognition, and psychosocial aspects. Those impairments affect their independence to perform daily activities, and furtherly hamper their participation and quality of life.
Source: Journal of Stroke and Cerebrovascular Diseases - December 29, 2022 Category: Neurology Authors: Jie Hao, Yuqi Pu, Zhen Chen, Ka-Chun Siu Source Type: research

Outcomes with IV tenecteplase and IV alteplase for acute ischemic stroke with or without thrombectomy in real-world settings in the United States
Although many stroke centers in United States are using intravenous (IV) tenecteplase (TNK) for acute ischemic stroke patients, there is paucity of comparative data between IV TNK and IV alteplase from real-world settings.
Source: Journal of Stroke and Cerebrovascular Diseases - December 6, 2022 Category: Neurology Authors: Adnan I. Qureshi, William I. Baskett, Navpreet K. Bains, Brandi R. French, Farhan Siddiq, Camilo R. Gomez, Chi-Ren Shyu Source Type: research

Evolution of endovascular stroke centers and disparities in access to stroke care in four Northeastern states: 2015-2019
Disparities exist throughout our healthcare system, especially related to access to care. Advanced stroke care for strokes is only available at selected endovascular centers (ESCs) in the United States. Although the number of ESCs increase each year, this does not necessarily reflect increased access to care. Here, we look at the evolution of ESC in four states and disparities in access to advanced stroke care.
Source: Journal of Stroke and Cerebrovascular Diseases - December 2, 2022 Category: Neurology Authors: Derek L. Isenberg, Chadd K. Kraus, Kevin A. Henry, Daniel Ackerman, Derek R. Cooney, Ethan Brandler, Alexander Kuc, Jason T. Nomura, Joseph Herres, Adam Sigal, Kelley Simon, Jenna Mylin, Nina T. Gentile Source Type: research

Methods and early recruitment of the Brain Attack Surveillance in Corpus Christi —Post-acute Care (BASIC-PAC) Project
Mexican Americans (MAs) are the most numerous sub-group of Latinx, the largest minority population in the United States. This important sub-group is aging and growing rapidly. Stroke incidence is similar in MAs compared with non-Hispanic whites (NHWs),1 and MA stroke survivors have worse neurologic, functional, cognitive and quality of life outcomes at 90-days post-stroke compared with NHWs for reasons that are not completely understood.2 Worse stroke outcomes in MAs are not fully explained by socio-demographics, including education and insurance, stroke treatment, stroke severity or subtype, or pre-stroke factors.
Source: Journal of Stroke and Cerebrovascular Diseases - November 3, 2022 Category: Neurology Authors: Lewis B. Morgenstern, Elizabeth M. Almendarez, Roshanak Mehdipanah, Madeline Kwicklis, Erin Case, Melinda A. Smith, Lynda D. Lisabeth Source Type: research

Trends in age and sex-specific prevalence of cancer and cancer subtypes in acute ischemic stroke from 2007-2019
To describe age and sex-specific prevalence of cancer in acute ischemic stroke (AIS) hospitalizations in the United States over the last decade.
Source: Journal of Stroke and Cerebrovascular Diseases - October 29, 2022 Category: Neurology Authors: Fadar Oliver Otite, Sana Somani, Ehimen Aneni, Emmanuel Akano, Smit D. Patel, Nnabuchi Anikpezie, Olaoluwatomi Lamikanra, Hesham Masoud, Julius Gene Latorre, Seemant Chaturvedi, Prachi Mehndiratta Source Type: research

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