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ACE Gene in Egyptian Ischemic Stroke Patients
Angiotensin-1-converting enzyme (ACE) is a crucial player in vascular homeostasis and in the pathogenesis of atherosclerosis and hypertension. The present study was conducted to determine whether there is an association between the ACE insertion/deletion (I/D) polymorphism and ischemic stroke in Egyptian population. Also, we analyzed the ACE gene I/D polymorphism as a risk factor for small-vessel (SV) versus large-vessel (LV) disease.
Source: Journal of Stroke and Cerebrovascular Diseases - July 24, 2016 Category: Neurology Authors: Magdy A. Mostafa, Lobna M. El-Nabiel, Nagia Aly Fahmy, Hany Aref, Edrees Shreef, Fathy Abd El-Tawab, Osama M. Abdulghany Source Type: research

Risk Factors of Nicardipine-Related Phlebitis in Acute Stroke Patients
Intravenous nicardipine is generally used to treat hypertension in acute stroke patients but is associated with frequent phlebitis. We aimed to identify the incidence and risk factors of phlebitis in such patients.
Source: Journal of Stroke and Cerebrovascular Diseases - July 12, 2016 Category: Neurology Authors: Kei Kawada, Tsuyoshi Ohta, Koudai Tanaka, Naoto Kadoguchi, Souichi Yamamoto, Masanori Morimoto Source Type: research

The Association between Changes in Behavioral Risk Factors for Stroke and Changes in Blood Pressure
High blood pressure (BP) is the leading risk factor for stroke. Data on the association of physical activity (PA), fruit and vegetable (F&V) consumption, and dietary sodium with hypertension are lacking in Hispanic communities. In the current report, we provide data on the association between changes in these stroke behavioral risk factors and BP change.
Source: Journal of Stroke and Cerebrovascular Diseases - June 20, 2016 Category: Neurology Authors: Lewis B. Morgenstern, Brisa N. Sánchez, Kathleen M. Conley, Melany C. Morgenstern, Emma Sais, Lesli E. Skolarus, Deborah A. Levine, Devin L. Brown Source Type: research

Bilateral Vein of Trolard Thrombosis
We report 2 cases of bilateral vein of Trolard thrombosis; one with and the other without dural sinus involvement. To our knowledge, there have been no cases of bilateral vein of Trolard thrombosis reported in literature. The clinical presentation of cerebral venous thrombosis is variable; patients can present with isolated intracranial hypertension, focal neurological abnormalities, seizures, or encephalopathy.
Source: Journal of Stroke and Cerebrovascular Diseases - May 23, 2016 Category: Neurology Authors: Sanskriti Mishra, Anand V. Patel, Jeffrey M. Katz, Avi Setton, Richard B. Libman Tags: Case Studies Source Type: research

Association of Brachial-Ankle Pulse Wave Velocity with Asymptomatic Intracranial Arterial Stenosis in Hypertension Patients
Intracranial arterial stenosis is a common cause of ischemic stroke in Asians. We therefore sought to explore the relationship of brachial-ankle pulse wave velocity and intracranial arterial stenosis in 834 stroke-free hypertensive patients.
Source: Journal of Stroke and Cerebrovascular Diseases - May 11, 2016 Category: Neurology Authors: Yan Wang, Jin Zhang, Yuesheng Qain, Xiaofeng Tang, Huawei Ling, Kemin Chen, Yan Li, Pingjin Gao, Dingliang Zhu Source Type: research

Poor Hypertension Control and Longer Transport Times Are Associated with Worse Outcome in Drip-and-Ship Stroke Patients
The “drip-and-ship” paradigm is an important treatment modality for acute ischemic stroke (AIS) patients who do not have immediate access to a comprehensive stroke center (CSC). Intravenous thrombolysis is initiated at a primary stroke center followed by expeditious transfer to a CSC. We sought to d etermine factors associated with poor outcomes in drip-and-ship AIS patients transferred to a CSC.
Source: Journal of Stroke and Cerebrovascular Diseases - May 4, 2016 Category: Neurology Authors: Thomas V. Kodankandath, Jane Shaji, Nina Kohn, Rohan Arora, Elliott Salamon, Richard B. Libman, Jeffrey M. Katz Source Type: research

High Morning and Bedtime Home Blood Pressures Strongly Predict for Post-Stroke Cognitive Impairment
Hypertension may be the most modifiable risk factor for post-stroke cognitive impairment (PSCI). We investigated how home blood pressure (HBP) can predict PSCI as well as stroke recurrence.
Source: Journal of Stroke and Cerebrovascular Diseases - May 1, 2016 Category: Neurology Authors: Yasumasa Yamamoto, Yoshinari Nagakane, Yasuhiro Tomii, Ichiro Akiguchi Source Type: research

Assessment of Risk of Aneurysmal Rupture in Patients with Normotensives, Controlled Hypertension, and Uncontrolled Hypertension
The prevalence of hypertension in patients with intracranial aneurysms has been an increased concern, but it is not well understood if uncontrolled hypertension has impact on aneurysmal rupture. The aim of this study was to determine whether the risk of aneurysmal rupture is higher in uncontrolled hypertensive cohorts than in controlled hypertensive cohorts and normotensive cohorts.
Source: Journal of Stroke and Cerebrovascular Diseases - April 13, 2016 Category: Neurology Authors: Zenghui Qian, Huibin Kang, Ke Tang, Chuhan Jiang, Zhongxue Wu, Youxiang Li, Aihua Liu Source Type: research

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