• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

87. Anodal transcranial direct current stimulation of motor cortex does not ameliorates spasticity in multiple sclerosis
Spasticity is a common disorder and a major cause of a long-term disability in patients with multiple sclerosis (MS). Transcranial direct current stimulation (tDCs) is a potential tool to improve motor deficits in several neurological disease and, recently, it has been proposed as effective in decreasing spasticity after stroke. To assess whether anodal tDCS is effective in modulating lower limb spasticity in MS patients. We performed a single-centre randomized, double-blind, sham-controlled study to investigate efficacy of anodal vs sham tDCs in 20 relapsing-remitting MS patients.
Source: Clinical Neurophysiology - December 13, 2014 Category: Neuroscience Authors: R. Iodice, F. Manganelli, L. Ruggiero, R. Dubbioso, L. Santoro Source Type: research

Comparison of brainstem reflex abnormalities in patients with multiple sclerosis, Behçet and stroke and its topodiagnostic value
Our current understanding of brainstem reflex physiology comes chiefly from the classic anatomical–functional correlation studies that traced the central circuits underlying brainstem reflexes and establishing reflex abnormalities as markers for specific areas of lesion. Our aim is to investigate the correlation between the brainstem reflex abnormalities and lesion localization in three different diseases with brainstem lesions.
Source: Clinical Neurophysiology - February 11, 2016 Category: Neuroscience Authors: R. Inan, F. Yavlal, M.E. Kiziltan, G. Kiziltas, S. Saip, U. Uygunoglu Source Type: research

Cerebellar transcranial direct current stimulation improves adaptive postural control
Adaptive postural control is essential for almost all aspects of every day life. Impaired postural control results in substantial functional limitations in advanced age (Maki and McIlroy, 1996) and in pathological ageing conditions like stroke (Beyaert et al., 2015), Parkinson ’s disease (Schoneburg et al., 2013) or multiple sclerosis (Huisinga et al., 2012). Although rehabilitation and conditioning programs have shown promising results in recovery of postural control, those interventions are typically time and cost intensive and may only yield moderate effects (Howard- Wilsher et al., 2016; Smania et al., 2011; Yitayeh and Teshome, 2016).
Source: Clinical Neurophysiology - October 20, 2017 Category: Neuroscience Authors: Peter Poortvliet, Billie Hsieh, Andrew Cresswell, Jacky Au, Marcus Meinzer Source Type: research

Spasticity in adults with cerebral palsy and multiple sclerosis measured by objective clinically applicable technique
Spasticity occurs frequently following lesions of central motor pathways in neurological disorders such as stroke (Malhotra et al., 2009; Sommerfeld et al., 2012), spinal cord injury (Sheean, 2002), multiple sclerosis (MS) (Sinkjaer et al., 1993; Mayer, 1997) and cerebral palsy (CP) (Gracies, 2005). Spasticity is most commonly defined as a velocity dependent increase in muscle tone with exaggeration of the stretch reflex circuitry (Lance, 1980). However, in the clinic a somewhat broader understanding of spasticity, which also includes sustained muscle contractions such as spasms and spastic dystonia as well as alterations ...
Source: Clinical Neurophysiology - July 15, 2018 Category: Neuroscience Authors: Tomofumi Yamaguchi, Tue Hvass Petersen, Henrik Kirk, Christian Forman, Christian Svane, Mathilde Kofoed-Hansen, Finn Boesen, Jakob Lorentzen Source Type: research