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Comparison of brainstem reflex abnormalities in patients with multiple sclerosis, Behçet and stroke and its topodiagnostic value
Our current understanding of brainstem reflex physiology comes chiefly from the classic anatomical–functional correlation studies that traced the central circuits underlying brainstem reflexes and establishing reflex abnormalities as markers for specific areas of lesion. Our aim is to investigate the correlation between the brainstem reflex abnormalities and lesion localization in three different diseases with brainstem lesions.
Source: Clinical Neurophysiology - February 11, 2016 Category: Neuroscience Authors: R. Inan, F. Yavlal, M.E. Kiziltan, G. Kiziltas, S. Saip, U. Uygunoglu Source Type: research

87. Anodal transcranial direct current stimulation of motor cortex does not ameliorates spasticity in multiple sclerosis
Spasticity is a common disorder and a major cause of a long-term disability in patients with multiple sclerosis (MS). Transcranial direct current stimulation (tDCs) is a potential tool to improve motor deficits in several neurological disease and, recently, it has been proposed as effective in decreasing spasticity after stroke. To assess whether anodal tDCS is effective in modulating lower limb spasticity in MS patients. We performed a single-centre randomized, double-blind, sham-controlled study to investigate efficacy of anodal vs sham tDCs in 20 relapsing-remitting MS patients.
Source: Clinical Neurophysiology - December 13, 2014 Category: Neuroscience Authors: R. Iodice, F. Manganelli, L. Ruggiero, R. Dubbioso, L. Santoro Source Type: research