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Intravenous infusion of mesenchymal stem cells promotes functional recovery in a rat model of chronic cerebral infarction.
CONCLUSIONSThese results indicate that the systemic infusion of MSCs results in functional improvement, which is associated with structural changes in the chronic phase of cerebral infarction, including in the stabilization of the BBB. PMID: 30485210 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - October 1, 2018 Category: Neurosurgery Tags: J Neurosurg Source Type: research

Brain repair by hematopoietic growth factors in the subacute phase of traumatic brain injury.
CONCLUSIONS SCF + G-CSF treatment in the subacute phase of TBI restored TBI-impaired spatial learning and memory, prevented posttraumatic anxiety and risk-taking behavior, inhibited TBI-induced neurodegeneration, and enhanced neural network remodeling. These findings suggest the therapeutic potential of hematopoietic growth factors for brain repair in the subacute phase of TBI. PMID: 29372883 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - January 26, 2018 Category: Neurosurgery Authors: Toshkezi G, Kyle M, Longo SL, Chin LS, Zhao LR Tags: J Neurosurg Source Type: research