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Brain Transforming Growth Factor-{beta} Resists Hypertension Via Regulating Microglial Activation Basic Sciences
Conclusions—Our results identify that TGF-β–modulated microglia are critical to keeping brain homeostasis responding to hypertensive disturbance.
Source: Stroke - August 28, 2017 Category: Neurology Authors: You Li, Xiao Z. Shen, Liang Li, Tuantuan V. Zhao, Kenneth E. Bernstein, Alan K. Johnson, Patrick Lyden, Jianmin Fang, Peng Shi Tags: Hypertension Original Contributions Source Type: research

Human Muse Cells Reconstruct Neuronal Circuitry in Subacute Lacunar Stroke Model Basic Sciences
Conclusions—Transplantation at the delayed subacute phase showed muse cells differentiated into neural cells, facilitated neural reconstruction, improved functions, and displayed solid safety outcomes over prolonged graft maturation period, indicating their therapeutic potential for lacunar stroke.
Source: Stroke - January 22, 2017 Category: Neurology Authors: Hiroki Uchida, Kuniyasu Niizuma, Yoshihiro Kushida, Shohei Wakao, Teiji Tominaga, Cesario V. Borlongan, Mari Dezawa Tags: Cell Therapy, Stem Cells, Translational Studies, Ischemic Stroke Original Contributions Source Type: research