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Risk of Ischemic and Hemorrhagic Strokes in Occult and Manifest Cancers Clinical Sciences
Conclusions—Cancer, occult and manifest, is associated with increased risks for stroke. The increased risk is linked mainly to cancers related to smoking.
Source: Stroke - June 25, 2018 Category: Neurology Authors: Klaus Kaae Andersen, Tom Skyhoȷ Olsen Tags: Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

High Serum Level of Matrix Metalloproteinase-7 Is Associated With Increased Risk of Spontaneous Subarachnoid Hemorrhage Clinical Sciences
Conclusions—High serum level of MMP-7 was associated with increased risk of incident spontaneous SAH, independently of the main risk factors for SAH. High serum levels of MMP-2 and MMP-9 did not predict SAH risk.
Source: Stroke - June 25, 2018 Category: Neurology Authors: Martin Soderholm, Gunilla Nordin Fredrikson, Jan Nilsson, Gunnar Engstrom Tags: Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage Original Contributions Source Type: research

Association of Cancer Cell Type and Extracellular Vesicles With Coagulopathy in Patients With Lung Cancer and Stroke Brief Report
Conclusions—Our findings indicate that cancer cell type is associated with circulating EV levels and coagulopathy in patients with lung cancer and stroke.
Source: Stroke - April 23, 2018 Category: Neurology Authors: Jong-Won Chung, Yeon Hee Cho, Myung-Ju Ahn, Mi Ji Lee, Gyeong-Moon Kim, Chin-Sang Chung, Oh Young Bang Tags: Biomarkers, Mechanisms, Translational Studies, Cerebrovascular Disease/Stroke, Thrombosis Brief Reports Source Type: research

Prospective Study of Fasting Blood Glucose and Intracerebral Hemorrhagic Risk Clinical Sciences
The objective of the current study was to examine the potential impact of long-term fasting blood glucose concentration on subsequent risk of ICH.Methods—This prospective study included 96 110 participants of the Kailuan study, living in Kailuan community, Tangshan city, China, who were free of cardiovascular diseases and cancer at baseline (2006). Fasting blood glucose concentration was measured in 2006, 2008, 2010, and 2012. Updated cumulative average fasting blood glucose concentration was used as primary exposure of the current study. Incident ICH from 2006 to 2015 was confirmed by review of medical records.Results...
Source: Stroke - December 22, 2017 Category: Neurology Authors: Cheng Jin, Guohong Li, Kathryn M. Rexrode, Mahmut E. Gurol, Xiaodong Yuan, Ying Hui, Chunyu Ruan, Anand Vaidya, Yanxiu Wang, Shouling Wu, Xiang Gao Tags: Cardiovascular Disease, Diabetes, Type 2, Epidemiology, Risk Factors, Intracranial Hemorrhage Original Contributions Source Type: research

Substitution of Linoleic Acid for Other Macronutrients and the Risk of Ischemic Stroke Clinical Sciences
Conclusions—This study suggests that replacing saturated fatty acid, glycemic carbohydrate, or monounsaturated fatty acid with linoleic acid may be associated with a lower risk of ischemic stroke.
Source: Stroke - November 27, 2017 Category: Neurology Authors: Stine K. Veno, Erik B. Schmidt, Marianne U. Jakobsen, Soren Lundbye–Christensen, Flemming W. Bach, Kim Overvad Tags: Diet and Nutrition, Epidemiology, Ischemic Stroke Original Contributions Source Type: research

Whole Grain Consumption and Risk of Ischemic Stroke Clinical Sciences
Conclusions—Although overall consumption of whole grains was not associated with lower risk of ischemic stroke, greater consumption of whole grain cold breakfast cereal and bran was significantly associated with a lower risk of ischemic stroke. More studies are needed to replicate these associations between individual whole grain foods and risk of ischemic stroke among other populations.
Source: Stroke - November 27, 2017 Category: Neurology Authors: Juan Juan, Gang Liu, Walter C. Willett, Frank B. Hu, Kathryn M. Rexrode, Qi Sun Tags: Diet and Nutrition, Epidemiology, Ischemic Stroke Original Contributions Source Type: research

Eosinophil Cationic Protein, Carotid Plaque, and Incidence of Stroke Clinical Sciences
Conclusions—High ECP is associated with increased incidence of IS. The association between ECP and IS was also present in the subgroup with carotid plaque.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Johannes Sundstrom, Martin Soderholm, Yan Borne, Jan Nilsson, Margaretha Persson, Gerd Ostling, Olle Melander, Marȷu Orho–Melander, Gunnar Engstrom Tags: Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke, Ischemic Stroke Original Contributions Source Type: research

Tumor Necrosis Factor Receptor 1 and 2 Are Associated With Risk of Intracerebral Hemorrhage Clinical Sciences
Conclusions—High plasma levels of TNFR1 and TNFR2 were associated with incident ICH, most clearly with ICH of nonlobar location. The results suggest that tumor necrosis factor–mediated inflammation could be associated with vascular changes preceding ICH.
Source: Stroke - September 25, 2017 Category: Neurology Authors: Edith H. Svensson, Martin Soderholm, Kasim Abul–Kasim, Gunnar Engstrom Tags: Risk Factors, Cerebrovascular Disease/Stroke, Intracranial Hemorrhage Original Contributions Source Type: research

Daily Total Physical Activity and Incident Stroke Clinical Sciences
Conclusions—For Japanese people, moderate levels of total physical activity, particularly achieved by moderate-intensity activities, may be optimal for stroke prevention because excessive vigorous-intensity activities might not be beneficial or even disadvantageous for prevention of hemorrhagic stroke.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Yasuhiko Kubota, Hiroyasu Iso, Kazumasa Yamagishi, Norie Sawada, Shoichiro Tsugane Tags: Epidemiology, Exercise, Primary Prevention, Race and Ethnicity, Risk Factors Original Contributions Source Type: research

Adherence to a Healthy Nordic Diet and Risk of Stroke Clinical Sciences
Conclusions—Our findings suggest that a healthy Nordic diet may be recommended for the prevention of stroke.
Source: Stroke - January 22, 2017 Category: Neurology Authors: Camilla Plambeck Hansen, Kim Overvad, Cecilie Kyro, Anȷa Olsen, Anne Tȷonneland, Soren Paaske Johnsen, Marianne Uhre Jakobsen, Christina Catherine Dahm Tags: Cardiovascular Disease, Diet and Nutrition, Epidemiology, Intracranial Hemorrhage, Ischemic Stroke Original Contributions Source Type: research

Venous Thrombotic Recurrence After Cerebral Venous Thrombosis Clinical Sciences
Conclusions—In our cohort of CVT patients followed on average for>6 years, subjects with a previous venous thrombotic event, cancer/malignant hemopathies, and unknown CVT causes were found to be at higher risk of recurrence.
Source: Stroke - January 22, 2017 Category: Neurology Authors: Paola Palazzo, Pierre Agius, Pierre Ingrand, Jonathan Ciron, Matthias Lamy, Aline Berthomet, Paul Cantagrel, Jean-Philippe Neau Tags: Cerebrovascular Disease/Stroke Original Contributions Source Type: research

Association of Major Depressive Episodes With Stroke Risk in a Prospective Study of 0.5 Million Chinese Adults Clinical Sciences
Conclusions— Findings from this large prospective study suggest that the presence of MDE is a risk factor for stroke, especially in smokers.
Source: Stroke - August 21, 2016 Category: Neurology Authors: Sun, J., Ma, H., Yu, C., Lv, J., Guo, Y., Bian, Z., Yang, L., Chen, Y., Shen, H., Chen, Z., Hu, Z., Li, L., on behalf of the China Kadoorie Biobank Collaborative Group Tags: Mental Health, Cerebrovascular Disease/Stroke Clinical Sciences Source Type: research

Orosomucoid, Carotid Plaque, and Incidence of Stroke Clinical Sciences
Conclusions— Elevated levels of orosomucoid are associated with increased occurrence of carotid plaque and increased incidence of ischemic stroke. The combination of high orosomucoid and carotid plaque substantially increase the risk of stroke.
Source: Stroke - June 26, 2016 Category: Neurology Authors: Berntsson, J., Ostling, G., Persson, M., Smith, J. G., Hedblad, B., Engstrom, G. Tags: Cardiovascular Disease, Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Association of Breakfast Intake With Incident Stroke and Coronary Heart Disease: The Japan Public Health Center-Based Study Clinical Sciences
Conclusions— The frequency of breakfast intake was inversely associated with the risk of stroke, especially cerebral hemorrhage in Japanese, suggesting that eating breakfast everyday may be beneficial for the prevention of stroke.
Source: Stroke - January 25, 2016 Category: Neurology Authors: Kubota, Y., Iso, H., Sawada, N., Tsugane, S., The JPHC Study Group Tags: Cardiovascular Disease, Epidemiology, Primary Prevention, Risk Factors Clinical Sciences Source Type: research

Fibroblast Growth Factor 23 and Incidence of Subarachnoid Hemorrhage: Nested Case-Control Study Brief Reports
Conclusions— High FGF23 was associated with increased risk of incident SAH in subjects from the general population. Further studies should elucidate whether FGF23 is a causal risk factor for SAH, or could be used in risk prediction.
Source: Stroke - October 26, 2015 Category: Neurology Authors: Soderholm, M., Engstrom, G. Tags: Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage, Epidemiology Brief Reports Source Type: research

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