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Source: Circulation
Condition: Arrhythmia

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Total 57 results found since Jan 2013.

CIB2 Is a Novel Endogenous Repressor of Atrial Remodeling
CONCLUSIONS: Our data suggest that CIB2 represents a novel endogenous and atrial-enriched regulator that protects against atrial remodeling and AF under stress conditions. Therefore, CIB2 may represent a new potential target for treating AF.PMID:37128899 | DOI:10.1161/CIRCULATIONAHA.122.062660
Source: Circulation - May 2, 2023 Category: Cardiology Authors: Yihui Wang Jizheng Wang Ling Shi Xiuyu Chen Desheng Li Chen Cui Kai Yang Minjie Lu Jinhua Huang Lei Zhang Fei Li Jinxi Wang Biyi Chen Bin Wang Duane D Hall Zhenwei Pan Jiang Hong Long-Sheng Song Lei Song Shihua Zhao Source Type: research

Association Between Age and Outcomes of Catheter Ablation Versus Medical Therapy for Atrial Fibrillation: Results from the CABANA Trial
Conclusions: We found age-based variations in clinical outcomes for catheter ablation compared with drug therapy, with the largest relative and absolute benefits of catheter ablation in younger patients. No prognostic benefits for ablation were seen in the oldest patients. No differences were found by age in treatment-related complications or in the relative effectiveness of catheter ablation in preventing recurrent atrial arrhythmias.PMID:34933570 | DOI:10.1161/CIRCULATIONAHA.121.055297
Source: Circulation - December 22, 2021 Category: Cardiology Authors: Tristram D Bahnson Anna Giczewska Daniel B Mark Andrea M Russo Kristi H Monahan Hussein R Al-Khalidi Adam P Silverstein Jeanne E Poole Kerry L Lee Douglas Packer Source Type: research

Functional Calsequestrin-1 Is Expressed in the Heart and Its Deficiency Is Causally Related to Malignant Hyperthermia-Like Arrhythmia
Conclusions: Casq1 is expressed in the heart, where it regulates SR Ca2+ release and heart rate. Casq1 deficiency independently causes MH/EHS-like ventricular arrhythmia by trigger-induced Casq1 oligomerization and a relief of its inhibitory effect on RyR2-mediated Ca2+ release, thus revealing a new inherited arrhythmia and a novel mechanism for MH/EHS arrhythmogenesis.PMID:34162222 | DOI:10.1161/CIRCULATIONAHA.121.053255
Source: Circulation - June 24, 2021 Category: Cardiology Authors: Zhipeng Sun Luqi Wang Lu Han Yue Wang Yuan Zhou Qiang Li Yongquan Wu Shaletanati Talabieke Yunlong Hou Lulin Wu Ronghua Liu Zhiping Fu Hongjie You Bai-Yan Li Yuanyuan Zheng Dali Luo Source Type: research

Obstructive Sleep Apnea and Cardiovascular Disease: A Scientific Statement From the American Heart Association
Circulation. 2021 Jun 21:CIR0000000000000988. doi: 10.1161/CIR.0000000000000988. Online ahead of print.ABSTRACTObstructive sleep apnea (OSA) is characterized by recurrent complete and partial upper airway obstructive events, resulting in intermittent hypoxemia, autonomic fluctuation, and sleep fragmentation. Approximately 34% and 17% of middle-aged men and women, respectively, meet the diagnostic criteria for OSA. Sleep disturbances are common and underdiagnosed among middle-aged and older adults, and the prevalence varies by race/ethnicity, sex, and obesity status. OSA prevalence is as high as 40% to 80% in patients with ...
Source: Circulation - June 21, 2021 Category: Cardiology Authors: Yerem Yeghiazarians Hani Jneid Jeremy R Tietjens Susan Redline Devin L Brown Nabil El-Sherif Reena Mehra Biykem Bozkurt Chiadi Ericson Ndumele Virend K Somers American Heart Association Council on Clinical Cardiology; Council on Peripheral Vascular Diseas Source Type: research