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Source: Circulation
Condition: Heart Failure
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Total 195 results found since Jan 2013.
Half-Dose Tenecteplase or Primary Percutaneous Coronary Intervention in Older Patients With ST-Segment-Elevation Myocardial Infarction in STREAM-2: A Randomized, Open-Label Trial
CONCLUSIONS: Halving the dose of tenecteplase in a pharmaco-invasive strategy in this early-presenting, older STEMI population was associated with electrocardiographic changes that were at least comparable to those after primary PCI. Similar clinical efficacy and angiographic end points occurred in both treatment groups. The risk of intracranial hemorrhage was higher with half-dose tenecteplase than with primary PCI. If timely PCI is unavailable, this pharmaco-invasive strategy is a reasonable alternative, provided that contraindications to fibrinolysis are observed and excess anticoagulation is avoided.REGISTRATION: URL: ...
Source: Circulation - July 13, 2023 Category: Cardiology Authors: Frans Van de Werf Arsen D Risti ć Oleg V Averkov Alexandra AriasMendoza Yves Lambert Jos é F Kerr Saraiva Pablo Sepulveda Fernando Rosell-Ortiz John K French Ljilja B Musi ć Katleen Vandenberghe Kris Bogaerts Cynthia M Westerhout Alain Pag ès Thierry Source Type: research
The Effect of Frailty on the Efficacy and Safety of Intensive Blood Pressure Control: A Post Hoc Analysis of the SPRINT Trial
CONCLUSIONS: Frailty status was a marker of high cardiovascular risk. Patients with frailty benefit similarly to other patients from intensive blood pressure control without an increased risk of serious adverse events.PMID:37401465 | DOI:10.1161/CIRCULATIONAHA.123.064003
Source: Circulation - July 4, 2023 Category: Cardiology Authors: Zhiyan Wang Xin Du Chang Hua Wenjie Li Hao Zhang Xinru Liu Yufeng Wang Chao Jiang Jiakun Guo Qiang Lv Craig S Anderson Jianzeng Dong Changsheng Ma Source Type: research
CIB2 Is a Novel Endogenous Repressor of Atrial Remodeling
CONCLUSIONS: Our data suggest that CIB2 represents a novel endogenous and atrial-enriched regulator that protects against atrial remodeling and AF under stress conditions. Therefore, CIB2 may represent a new potential target for treating AF.PMID:37128899 | DOI:10.1161/CIRCULATIONAHA.122.062660
Source: Circulation - May 2, 2023 Category: Cardiology Authors: Yihui Wang Jizheng Wang Ling Shi Xiuyu Chen Desheng Li Chen Cui Kai Yang Minjie Lu Jinhua Huang Lei Zhang Fei Li Jinxi Wang Biyi Chen Bin Wang Duane D Hall Zhenwei Pan Jiang Hong Long-Sheng Song Lei Song Shihua Zhao Source Type: research
Comparison of Unibody and Non-Unibody Endografts for Abdominal Aortic Aneurysm Repair in Medicare Beneficiaries: The SAFE-AAA Study
CONCLUSIONS: In the SAFE-AAA Study, unibody endografts failed to meet noninferiority compared with non-unibody endografts with respect to aortic reintervention, rupture, and mortality. These data support the urgency of instituting a prospective longitudinal surveillance program for monitoring safety events related to aortic stent grafts.PMID:36866664 | DOI:10.1161/CIRCULATIONAHA.122.062123
Source: Circulation - March 3, 2023 Category: Cardiology Authors: Eric A Secemsky Yang Song Tianyu Sun Carmen Gacchina Johnson Megan Gatski Li Wang Andrew Farb Robert E Lee Aurko Shaw Jiaman Xu Robert W Yeh Source Type: research
Exploring the Relationship Between Efpeglenatide Dose and Cardiovascular Outcomes in Type 2 Diabetes: Insights From the AMPLITUDE-O Trial
CONCLUSIONS: The graded salutary relationship between efpeglenatide dose and cardiovascular outcomes suggests that titrating efpeglenatide and potentially other glucagon-like peptide-1 receptor agonists to high doses may maximize their cardiovascular and renal benefits.REGISTRATION: URL: https://www.CLINICALTRIALS: gov; Unique identifier: NCT03496298.PMID:36802715 | DOI:10.1161/CIRCULATIONAHA.122.063716
Source: Circulation - February 21, 2023 Category: Cardiology Authors: Hertzel C Gerstein Zhuoru Li Chinthanie Ramasundarahettige Seungjae Baek Kelley R H Branch Stefano Del Prato Carolyn S P Lam Renato D Lopes Richard Pratley Julio Rosenstock Naveed Sattar Source Type: research
