• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Macrophage-based models for diagnostics and therapy development
Aim: Immunopathology plays important roles in the development of different life-threatening diseases, such as atherosclerosis and its consequences (acute myocardial infarction and stroke), cancer, chronic inflammatory diseases. Effective modulation of the immune system may significantly increase the efficacy of prevention and therapy efforts. We have developed a test system designed for complex analysis of human monocyte-derived macrophage activity in individuals to diagnose immunopathology and monitor treatment efficacy.
Source: Atherosclerosis - August 1, 2018 Category: Cardiology Authors: A. Melnichenko, T. Kirichenko, M. Stepanova, A. Orekhov Source Type: research

Fat or fit: The big oxymoron of (metabolically) healthy obesity
Among the major concerns for public health, the prevalence of obesity is raising worldwide with an inexorable pace. In 2014, over 600 million adults worldwide were obese (and more than 1.9 billion overweight) and current projections predict that over 1 billion individuals (reflecting approximately 20% of humankind) will be obese by 2030 [1,2]. Strong epidemiological evidence links obesity with increased morbidity and mortality for several diseases such as cardiovascular diseases (CVD), stroke, cancer, and diabetes, and current preventive and therapeutic strategies of most of these conditions require management of obesity a...
Source: Atherosclerosis - May 2, 2017 Category: Cardiology Authors: Donato Santovito Tags: Editorial Source Type: research

Bowel movement frequency and cardiovascular mortality, a matter of fibers and oxidative stress?
To the Editor, Hippocrates, the father of western medicine, believed that all disease begins in the gut. Today, the global obesity epidemic, resulting in serious diet-related diseases, including cardiovascular disease, stroke, hypertension, diabetes mellitus type 2 and certain forms of cancer, including colorectal cancer, reveals that his view is still relevant. The relation between diet and health and the resulting potential for disease prevention has increasingly been emphasized in health promotion messages over the last thirty years [1 –5].
Source: Atherosclerosis - August 20, 2016 Category: Cardiology Authors: Alphons J.M. Vermorken, Yali Cui, Robbert Kleerebezem, Emmanuel Andr ès Tags: Correspondence Source Type: research

Mediterranean Diet in patients with acute ischemic stroke: relationships between Mediterranean diet score, diagnostic subtype, and stroke severity index
Adherence to a Mediterranean Diet appears to reduce the risk of cardiovascular disease, cancer, Alzheimer’s disease, and Parkinson’s disease, as well as the risk of death due to cardiovascular disease. No study has addressed the association between diagnostic subtype of stroke and its severity and adherence to a Mediterranean Diet in subjects with acute ischemic stroke.
Source: Atherosclerosis - September 10, 2015 Category: Cardiology Authors: Antonino Tuttolomondo, Alessandra Casuccio, Carmelo Buttà, Rosaria Pecoraro, Domenico Di Raimondo, Vittoriano Della Corte, Valentina Arnao, Giuseppe Clemente, Carlo Maida, Irene Simonetta, Giuseppe Miceli, Benedetto Lucifora, Anna Cirrincione, Danilo Di Source Type: research

Overall diet quality and risk of stroke: A prospective cohort study in women
In conclusion, these findings suggest that a diet including a variety of healthy foods and few less healthy foods may reduce stroke risk.Highlights:
Source: Atherosclerosis - February 18, 2014 Category: Cardiology Authors: Susanna C. Larsson, Agneta Åkesson, Alicja Wolk Tags: Clinical & Population Research - Epidemiology, Biomarkers, Nutrition Source Type: research

The combination of Helicobacter pylori- and cytotoxin-associated gene-A seropositivity in relation to the risk of myocardial infarction in middle-aged Japanese: The Japan Public Health Center-based study
Conclusions: H. pylori infection was not significantly associated with risk of MI and stroke among middle-aged Japanese. However, CagA positivity tended to be associated with MI.Highlights:
Source: Atherosclerosis - September 1, 2013 Category: Cardiology Authors: Ai Ikeda, Hiroyasu Iso, Shizuka Sasazuki, Manami Inoue, Shoichiro Tsugane, for the JPHC Study Group Tags: Clinical & Population Research - Epidemiology, Biomarkers, Nutrition Source Type: research

Obesity paradox in peripheral vascular disease
To prevent cardiovascular diseases, it is essential to control risk factors, among which obesity is a world-wide issue that we are currently facing . Obesity was found to be an independent cardiovascular risk factor by the Framingham Heart study, in which the participants were followed up over 26 years; a higher risk was observed in both men and women whose body weights increased after the young adult years . It has been shown that obesity, particularly visceral obesity, is closely related not only to classical cardiovascular risk factors such as dyslipidemia, diabetes, and hypertension, but also to insulin resistance, abn...
Source: Atherosclerosis - June 3, 2013 Category: Cardiology Authors: Johji Kato Tags: Invited Commentaries Source Type: research

Liver enzymes and stroke risk in middle-aged German adults
Conclusions: Our data provide further evidence for a link between GGT, but not ALT and overall stroke suggesting that these biomarkers are involved in different pathways of disease development. Further studies are needed to clarify the putative relationships between ALT and subtypes of stroke.Highlights:
Source: Atherosclerosis - April 22, 2013 Category: Cardiology Authors: Cornelia Weikert, Dagmar Drogan, Romina di Giuseppe, Andreas Fritsche, Brian Buijsse, Ute Nöthlings, Stefan N. Willich, Klaus Berger, Heiner Boeing Tags: Epidemiology, Biomarkers, Nutrition Source Type: research

Total and specific fruit and vegetable consumption and risk of stroke: A prospective study
Conclusion: This study shows an inverse association of fruit and vegetable consumption with stroke risk. Particularly consumption of apples and pears and green leafy vegetables was inversely associated with stroke.Highlights: ► Fruit and vegetables is a heterogeneous food group with different content of nutrients. ► It remains unclear which fruit and vegetable subgroups that are most protective against stroke. ► We examined the relation between fruit and vegetable consumption and stroke risk. ► Particularly consumption of apples/pears and green leafy vegetables was inversely associated with stroke.
Source: Atherosclerosis - January 7, 2013 Category: Cardiology Authors: Susanna C. Larsson, Jarmo Virtamo, Alicja Wolk Tags: Epidemiology, Biomarkers, Nutrition Source Type: research