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Hyperthermia and Severe Rhabdomyolysis From Synthetic Cannabinoids Am J Emerg Med 2016;34:121.e1-2. Doi: 10.1016/j.Ajem.2015.05.052. Epub 2015 Jun 12
We read with great interest the case report by Sweeney et al. [1] discussing severe hyperthermia and rhabdomyolysis following a reported exposure to a synthetic cannabinoid receptor agonist (SCRA). SCRA exposures, first reported in NYC in 2010, were at an all-time high in 2015 [2]. Confirmed cases of significant SCRA-associated acute kidney injury, stroke, and acute psychosis are reported [3,4].
Source: The American Journal of Emergency Medicine - May 10, 2016 Category: Emergency Medicine Authors: Mark Su, Larissa Laskowski, Robert S. Hoffman Tags: Correspondence Source Type: research

Letter in response to: Hyperthermia and severe rhabdomyolysis from synthetic cannabinoids. Am J Emerg Med 2016;34:121.e1–2. doi: 10.1016/j.ajem.2015.05.052. Epub 2015 Jun. 12
We read with great interest the case report by Sweeney et al. [1] discussing severe hyperthermia and rhabdomyolysis following a reported exposure to a synthetic cannabinoid receptor agonist (SCRA). SCRA exposures, first reported in NYC in 2010, were at an all-time high in 2015 [2]. Confirmed cases of significant SCRA-associated acute kidney injury, stroke and acute psychosis are reported [3,4].
Source: The American Journal of Emergency Medicine - May 10, 2016 Category: Emergency Medicine Authors: Mark Su, Larissa Laskowski, Robert S. Hoffman Tags: Correspondence Source Type: research

Fatal heat stroke associated with topiramate therapy
A 40-year-old man with diabetes and seizure disorder was found at home unresponsive and “very hot to touch” by his father 40 minutes before emergency medical services arrival. His usual medications included topiramate, divalproex sodium, and rosiglitazone/metformin. Paramedics administered oxygen, intravenous fluids, and naloxone. They did not witness or report seizure activity. Upon emergency department arrival, the patient was unresponsive (Glasgow Coma Scale 3), hypotensive (94/50 mm Hg), and tachypneic (32 breaths per minute), with a heart rate of 60 beats per minute and elevated rectal temperature peaking at 43.2�...
Source: The American Journal of Emergency Medicine - September 3, 2013 Category: Emergency Medicine Authors: Stephen W Borron, Robert Woolard, Susan Watts Tags: Case Reports Source Type: research