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Endogenous brain protection: what the cerebral transcriptome teaches us.
Abstract Despite efforts to reduce mortality caused by stroke and perinatal asphyxia, these are still the 2(nd) largest cause of death worldwide in the age groups they affect. Furthermore, survivors of cerebral hypoxia-ischemia often suffer neurological morbidities. A better understanding of pathophysiological mechanisms in focal and global brain ischemia will contribute to the development of tailored therapeutic strategies. Similarly, insight in molecular pathways involved in preconditioning-induced brain protection will provide possibilities for future treatment. Microarray technology is a great tool for investi...
Source: Brain Research - April 5, 2014 Category: Neurology Authors: Cox-Limpens KE, Gavilanes AW, Zimmermann LJ, Vles JS Tags: Brain Res Source Type: research