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Source: Brain Research
Education: Training

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Total 24 results found since Jan 2013.

Effect of High-Frequency rTMS Combined with Bilateral Arm Training on Brain Functional Network in Patients with Chronic Stroke: An fNIRS study
CONCLUSIONS: These results suggest that the rTMS-BAT paradigm had additional effects on task-dependent brain functional reorganization. The engagement of the ipsilesional motor area in the functional network was associated with the motor impairment severity of stroke patients. fNIRS-based assessments may provide information about the neural mechanisms underlying combination interventions for stroke rehabilitation.PMID:37011721 | DOI:10.1016/j.brainres.2023.148357
Source: Brain Research - April 3, 2023 Category: Neurology Authors: Congcong Huo Gongcheng Xu Hui Xie Haihong Zhao Xuemin Zhang Wenhao Li Simin Zhang Jianfei Huo Huiyuan Li Aiping Sun Zengyong Li Source Type: research

Effectiveness and Electrophysiological Mechanisms of Focal Vibration on Upper Limb Motor Dysfunction in Patients with Subacute Stroke: A Randomized Controlled Trial
This study showed that FV was effective in improving upper limb motor function in subacute stroke patients. The underlying mechanism of FV may be that it enhances the efficacy of sensory pathways and induces plastic changes in the sensorimotor cortex.PMID:36990135 | DOI:10.1016/j.brainres.2023.148353
Source: Brain Research - March 29, 2023 Category: Neurology Authors: Lian Wang Saihua Wang Song Zhang Zulin Dou Tiecheng Guo Source Type: research

Neuroprotective Effects of Pre-Ischemic Exercise are linked to Expression of NT-3/NT-4 and TrkB/TrkC in Rats
CONCLUSION: The findings showed that pre-ischemic exercise can exert neuroprotective effectsvia NT-3 and NT-4 pathways against ischemia in hippocampal CA1 neurons and promote post-injury sensorimotor recovery.PMID:36646145 | DOI:10.1016/j.brainresbull.2023.01.004
Source: Brain Research - January 16, 2023 Category: Neurology Authors: AbdorrezaEghbal Moghanlou Mohtaram Yazdanian Sajad Roshani Abdullah Demirli Mehdi Seydyousefi Gerlinde A S Metz Zeinab Faghfoori Source Type: research

Variation of body  weight supported treadmill training parameters during a single session can modulate muscle activity patterns in post-stroke gait
Exp Brain Res. 2023 Jan 13. doi: 10.1007/s00221-023-06551-7. Online ahead of print.ABSTRACTEvidence supporting the benefits of locomotor training (LT) to improve walking ability following stroke are inconclusive and could likely be improved with a better understanding of the effects of individual parameters i.e., body weight support (BWS), speed, and therapist assistance and their interactions with walking ability and specific impairments. We evaluated changes in muscle activity of thirty-seven individuals with chronic stroke (> 6 months), in response to a single session of LT at their self-selected or fastest-comfortab...
Source: Brain Research - January 13, 2023 Category: Neurology Authors: Shraddha Srivastava Bryant A Seamon Carolynn Patten Steven A Kautz Source Type: research

Retraction notice to "Effects of rehabilitation training on apoptosis of nerve cells and the recovery of neural and motor functions in rats with ischemic stroke through the PI3K/Akt and Nrf2/ARE signaling pathways" Brain Res. Bull.  134 (2017) 236-245
Brain Res Bull. 2022 Nov 4;192:11. doi: 10.1016/j.brainresbull.2022.11.001. Online ahead of print.NO ABSTRACTPMID:36343567 | DOI:10.1016/j.brainresbull.2022.11.001
Source: Brain Research - November 7, 2022 Category: Neurology Authors: Xiao-Fei Jin Shan Wang Min Shen Xin Wen Xin-Rui Han Jun-Chang Wu Gao-Zhuo Tang Dong-Mei Wu Jun Lu Yuan-Lin Zheng Source Type: research

Treadmill exercise decreases cerebral edema in rats with local cerebral infarction by modulating AQP4 polar expression through the caveolin-1/TRPV4 signaling pathway
This study investigated the influence of treadmill exercise on brain edema and the mechanism of its formation and elimination. The MCAO model was established with Sprague-Dawley (SD) rats, and lentivirus-mediated caveolin-1 shRNA was used to investigate the role of caveolin-1 in brain edema. As expected, we found that treadmill exercise has a beneficial effect on brain edema after stroke. Training led to a significant increase in the expression of caveolin-1 and TRPV4; and reduced brain water content and blood-brain barrier (BBB) damage. This treatment also changed the localization of aquaporin-4 (AQP4). Moreover, the effe...
Source: Brain Research - August 12, 2022 Category: Neurology Authors: Anqi Zhu Yao Lin Xuanbo Hu Zaizai Lin Yongqiang Lin Qingfeng Xie Shaobo Ni Hui Cheng Qiaoya Lu Shanshan Lai Guoyuan Pan Xiang Chen Wei Pang Chan Liu Source Type: research

Cortical mapping of active and passive upper limb training in stroke patients and healthy people: A functional near-infrared spectroscopy study
Brain Res. 2022 Apr 29:147935. doi: 10.1016/j.brainres.2022.147935. Online ahead of print.ABSTRACTActive exercise for upper limb training has been widely used to improve hemiplegic upper limb function, and its effect may be boosted by extrinsic visual feedback. The passive movement of the hemiplegic upper limb is also commonly used. We conducted a functional near-infrared spectroscopy experiment to compare cortical activation during the following three conditions: active left upper limb movement (on the hemiplegic sides in stroke patients), with or without extrinsic motor performance visual feedback (LAV, LAnV), and passiv...
Source: Brain Research - May 2, 2022 Category: Neurology Authors: Weili Xia Rongxia Dai Xiaojin Xu Baoyu Huai Zhongfei Bai Jiaqi Zhang Minxia Jin Wenxin Niu Source Type: research

Different training patterns at recovery stage improve cognitive function in ischemic stroke rats through regulation of the axonal growth inhibitor pathway
This study investigated the effects of SRT and RWE, at the recovery stage, on the cognitive function of transient middle cerebral artery occlusion (tMCAO) rats and explored their association with NgR1/Rho-A/ROCK/LOTUS/LGI1 signaling. Adult Sprague-Dawley rats (n = 55) were divided into four groups after pretraining: SRT, RWE, tMCAO, and Sham. Rats were subjected to modified neurological severity score (mNSS) measurements and forelimb grip strength and the Morris water maze tests. Using immunofluorescence and western blotting, we evaluated axonal growth inhibitor expression in the peri-infarct cortex on days 28 and 56 after...
Source: Brain Research - December 31, 2021 Category: Neurology Authors: Chao Li Ruifang Sun Jiemei Chen Jiena Hong Ju Sun Yan Zeng Xue Zhang Zulin Dou Hongmei Wen Source Type: research