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Electrocardiographic Morphology-Voltage-P-Wave-Duration (MVP) Score to Select Patients for Continuous Atrial Fibrillation Screening to Prevent Stroke
Morphology-voltage-P-wave-duration (MVP) score combining P-wave duration (PWD), P-wave voltage in lead I (PWVI), and interatrial block (IAB) has been demonstrated to predict atrial fibrillation (AF). Therefore, this study aimed to examine MVP score and its P-wave components as potential predictors of AF screening effects on stroke prevention. This was a secondary analysis of the LOOP Study (Atrial Fibrillation detected by Continuous ECG Monitoring using Implantable Loop Recorder to prevent Stroke in High-risk Individuals) which randomized older persons (aged 70 to 90  years) with additional stroke risk factors to either c...
Source: The American Journal of Cardiology - September 2, 2023 Category: Cardiology Authors: Lucas Yixi Xing, S øren Zöga Diederichsen, Søren Højberg, Derk Krieger, Claus Graff, Morten Salling Olesen, Jonas Bille Nielsen, Axel Brandes, Lars Køber, Ketil Jørgen Haugan, Jesper Hastrup Svendsen Source Type: research

Atrial Myopathy and Ischemic Stroke in Heart Failure With Preserved Ejection Fraction
We examined the hypothesis that atrial myopathy may be associated with ischemic stroke in patients with heart failure with preserved ejection fraction. This is an exploratory, post hoc analysis of the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) trial. Patients with sinus rhythm documented at baseline electrocardiogram and without known AF were included in this analysis.
Source: The American Journal of Cardiology - July 27, 2023 Category: Cardiology Authors: Kassem Farhat, Khaled Elkholey, Zain Ul Abideen Asad, Stavros Stavrakis Source Type: research

Machine Learning-Based Prediction of Atrial Fibrillation Risk Using Electronic Medical Records in Older Aged Patients
Atrial fibrillation (AF) is an independent risk factor that increases the risk of stroke 5-fold. The purpose of our study was to develop a 1-year new-onset AF predictive model by machine learning based on 3-year medical information without electrocardiograms in our database to identify AF risk in older aged patients. We developed the predictive model according to the Taipei Medical University clinical research database electronic medical records, including diagnostic codes, medications, and laboratory data.
Source: The American Journal of Cardiology - May 18, 2023 Category: Cardiology Authors: Yung-Ta Kao, Chun-Yao Huang, Yu-Ann Fang, Ju-Chi Liu, Tzu-Hao Chang Source Type: research

Relation of Electrocardiographic Abnormal P-Wave Axis With Stroke Mortality in the General Population
We examined the association of abnormal aPWA with stroke mortality in 7,359 participants (60.0 ± 13.4 years, 51.9% women, 49.8% White) without cardiovascular (CV) disease (CVD) from the Third National Health and Nutrition Examination Survey. aPWA was defined as any value75 °.
Source: The American Journal of Cardiology - August 6, 2022 Category: Cardiology Authors: Muhammad Imtiaz Ahmad, Luqman-Arafath TK, Muhammad Ali Anees, Lin Yee Chen, Elsayed Z. Soliman Source Type: research

Relation of Atrial Fibrillation to Cognitive Decline (from the REasons for Geographic and Racial Differences in Stroke REGARDS Study)
The association of atrial fibrillation (AF) with cognitive function remains unclear, especially among racially/geographically diverse populations. This analysis included 25,980 black and white adults, aged 48+, from the national REasons for Geographic and Racial Differences in Stroke (REGARDS) cohort, free from cognitive impairment and stroke at baseline. Baseline AF was identified by self-reported medical history or electrocardiogram (ECG). Cognitive testing was conducted yearly with the Six Item Screener (SIS) to define impairment and at 2-year intervals to assess decline on: animal naming and letter fluency, Montreal Co...
Source: The American Journal of Cardiology - March 5, 2021 Category: Cardiology Authors: Margie J. Bailey, Elsayed Z. Soliman, Leslie A. McClure, George Howard, Virginia J. Howard, Suzanne E. Judd, Fred Unverzagt, Virginia Wadley, Bonnie C. Sachs, Timothy Hughes Source Type: research

Objectively Measured Physical Activity and the Risk of Atrial Fibrillation (From the REGARDS Study)
The association between objectively measured physical activity and atrial fibrillation (AF) has not been examined. Therefore, we examined the association between moderate and vigorous physical activity (MVPA) with incident AF in 5,147 participants who completed accelerometer assessment for 4 to 7 consecutive days in the REasons for Geographic and Racial Differences in Stroke (REGARDS) study. MVPA was defined as>1065 counts/minute, and daily mean time spent in MVPA was computed. Incident AF was identified during follow-up by a study-scheduled electrocardiogram and also from self-reported medical history of a physician diagnosis.
Source: The American Journal of Cardiology - May 13, 2020 Category: Cardiology Authors: Wesley T. O'Neal, Aleena Bennett, Matthew J. Singleton, Suzanne E. Judd, George Howard, Virginia J. Howard, Steven P. Hooker, Elsayed Z. Soliman Source Type: research

Sex Differences in Risk Factors for Incident Atrial Fibrillation (From the Reasons for Geographic And Racial Differences in Stroke (REGARDS) Study)
We examined whether the sex differences in atrial fibrillation (AF) is related to difference in risk factors leading to AF or due to a differential impact of the same risk factors in 11,806 participants (55.2 % women) from the REGARDS study. Incident AF was ascertained by electrocardiograms and medical history at a follow-up examination. Backwards elimination logistic regression was used to identify AF risk factors in men and women, separately. Over a median follow-up of 9.0 years, 588 (11.1%) men and 428 (6.6%) women (p-value
Source: The American Journal of Cardiology - February 9, 2019 Category: Cardiology Authors: Abhishek Bose, Wesley T. O'Neal, Chengyi Wu, Leslie A. McClure, Suzanne E. Judd, Virginia J. Howard, George Howard, Elsayed Z. Soliman Source Type: research

Relation of Platelet Parameters with Incident Cardiovascular Disease (The Dongfeng-Tongji Cohort Study)
This study aimed to investigate the above-mentioned prospective relations in the middle-aged and older Chinese populations based on the Dongfeng-Tongji (DFTJ) cohort. We included 31,751 participants who were free of coronary heart disease (CHD), stroke, cancer, or severely abnormal electrocardiogram (ECG) at baseline.
Source: The American Journal of Cardiology - October 23, 2018 Category: Cardiology Authors: Shiqi He, Wenhui Lei, Jun Li, Kuai Yu, Yanqiu Yu, Lue Zhou, Xiaomin Zhang, Meian He, Huan Guo, Handong Yang, Tangchun Wu Source Type: research

Relation of Elevated Resting Heart Rate in Mid-Life to Cognitive Decline Over 20-years (from the Atherosclerosis Risk in Communities ARIC Study)
Resting heart rate (RHR) is independently associated with cardiovascular disease (CVD) risk. We determined whether RHR, measured in mid-life, is also associated with cognitive decline. We studied 13,720 middle-aged white and black ARIC participants without a prior history of stroke or atrial fibrillation. RHR was obtained from a 12-lead resting electrocardiogram at the baseline visit (1990-1992) and categorized into groups as
Source: The American Journal of Cardiology - October 20, 2018 Category: Cardiology Authors: Stephanie Wang, Oluwaseun E. Fashanu, Di Zhao, Eliseo Guallar, Rebecca F. Gottesman, Andrea L.C. Schneider, John W. McEvoy, Faye L. Norby, Amer I. Aladin, Alvaro Alonso, Erin D. Michos Source Type: research

Relation of Elevated Resting Heart Rate in Mid-Life to Cognitive Decline Over 20 Years (from the Atherosclerosis Risk in Communities ARIC Study)
Resting heart rate (RHR) is independently associated with cardiovascular disease (CVD) risk. We determined whether RHR, measured in mid-life, is also associated with cognitive decline. We studied 13,720 middle-aged white and black ARIC participants without a history of stroke or atrial fibrillation. RHR was obtained from a 12-lead resting electrocardiogram at the baseline visit (1990 to 1992) and categorized into groups as
Source: The American Journal of Cardiology - October 20, 2018 Category: Cardiology Authors: Stephanie Wang, Oluwaseun E. Fashanu, Di Zhao, Eliseo Guallar, Rebecca F. Gottesman, Andrea L.C. Schneider, John W. McEvoy, Faye L. Norby, Amer I. Aladin, Alvaro Alonso, Erin D. Michos Source Type: research

Relation of Electrocardiographic Left Atrial Abnormalities to Risk of Stroke in Patients with Atrial Fibrillation
The P wave terminal force in lead V1 (PTFV1) on the 12-lead ECG quantifies left atrial (LA) structural and electrophysiological abnormalities. We aimed to evaluate the association between PTFV1 and cerebrovascular accident (CVA) as well as LA structure and function in patients with atrial fibrillation (AF). We conducted a cross-sectional study of 229 patients with AF (60 ±10 years, 72% male) with (n=21) and without (n=208) a history of CVA, who underwent pre-ablation ECG and cardiac magnetic resonance (CMR) in sinus rhythm.
Source: The American Journal of Cardiology - May 2, 2018 Category: Cardiology Authors: Yuko Y. Inoue, Esra G. Ipek, Irfan M. Khurram, Luisa Ciuffo, Jonathan Chrispin, Stefan L. Zimmerman, Joseph E. Marine, John Rickard, David D. Spragg, Saman Nazarian, Kengo Kusano, Joao A. Lima, Ronald D. Berger, Hugh Calkins, Hiroshi Ashikaga Source Type: research

Frequency of Electrocardiographic Abnormalities in Patients With Psoriasis
Psoriasis is a chronic inflammatory disease associated with cardiovascular disease, for example, myocardial infarction, stroke, cardiovascular death, and arrhythmias. The resting electrocardiogram may carry prognostic information, but limited evidence is available of electrocardiographic findings in subjects with psoriasis. The electrocardiographic results were compared between 1,131 subjects with self-reported psoriasis and 18,397 controls participating in the Danish General Suburban Population Study (GESUS).
Source: The American Journal of Cardiology - February 4, 2018 Category: Cardiology Authors: Peter Riis Hansen, Christian Rimer Juhl, Jonas Lynggaard Isaksen, Gregor Borut Jemec, Christina Ellervik, J ørgen Kim Kanters Tags: Miscellaneous Source Type: research

Frequency of Electrocardiographic Abnormalities in Patients with Psoriasis
Psoriasis is a chronic inflammatory disease associated with cardiovascular disease, e.g., myocardial infarction, stroke, cardiovascular death, and arrhythmias. The resting electrocardiogram (ECG) may carry prognostic information but limited evidence is available of ECG findings in subjects with psoriasis. The ECG was compared between 1,131 individuals with self-reported psoriasis and 18,397 controls participating in the Danish General Suburban Population Study. The mean heart rate was marginally increased in patients with psoriasis (66 ± 11 vs.
Source: The American Journal of Cardiology - February 4, 2018 Category: Cardiology Authors: Peter Riis Hansen, Christian Rimer Juhl, Jonas Lynggaard Isaksen, Gregor Borut Jemec, Christina Ellervik, J ørgen Kim Kanters Source Type: research

Frequency of Inverted Electrocardiographic T Waves (Cerebral T Waves) in Patients With Acute Strokes and Their Relation to Left Ventricular Wall Motion Abnormalities
Transient, symmetric, and deep inverted electrocardiogram (ECG) T waves in the setting of stroke, commonly referred to as cerebral T waves, are rare, and the underlying mechanism is unclear. Our study aimed to test the hypothesis that cerebral T waves are associated with transient cardiac dysfunction. This retrospective study included 800 patients admitted with the primary diagnosis of hemorrhagic or ischemic stroke. ECGs were examined for cerebral T waves, defined as T-wave inversion of ≥5 mm depth in ≥4 contiguous precordial leads.
Source: The American Journal of Cardiology - November 14, 2017 Category: Cardiology Authors: Jeremy Stone, Victor Mor-Avi, Agnieszka Ardelt, Roberto M. Lang Source Type: research

Frequency of Inverted Electrocardiographic T-Waves (Cerebral T-Waves) in Patients with Acute Strokes and Their Relation to Left Ventricular Wall Motion Abnormalities
Transient, symmetric and deep inverted ECG T-waves in the setting of stroke, commonly referred to as cerebral T-waves, are rare and the underlying mechanism is unclear. Our study aimed to test the hypothesis that cerebral T-waves are associated with transient cardiac dysfunction. This retrospective study included 800 patients admitted with the primary diagnosis of hemorrhagic or ischemic stroke. Electrocardiograms were examined for cerebral T waves, defined as T-wave inversion of ≥5 mm depth in ≥4 contiguous precordial leads.
Source: The American Journal of Cardiology - November 14, 2017 Category: Cardiology Authors: Jeremy Stone, Victor Mor-Avi, Agnieszka Ardelt, Roberto M. Lang Source Type: research

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