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Source: Journal of Hypertension
Countries: South Africa Health

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Total 2 results found since Jan 2013.

Independent relationships between renal mechanisms and systemic flow, but not resistance to flow in primary hypertension in Africa
Aims: Whether renal mechanisms of hypertension primarily translate into increases in systemic vascular resistance (SVR) in all populations is uncertain. We determined whether renal mechanisms associate with either increases in SVR (and impedance to flow) or systemic flow in a community of African ancestry. Method: In a South African community sampled across the full adult age range (n = 546), we assessed stroke volume (SV), peak aortic flow (Q), SVR, characteristic impedance (Zc) and total arterial compliance (TAC) from velocity and diameter measurements in the outflow tract (echocardiography) and central ar...
Source: Journal of Hypertension - November 19, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Renal aspects Source Type: research

Carotid intima–media thickness, but not chronic kidney disease independently associates with noncardiac arterial vascular events in South Africa
Aim: Although chronic kidney disease (CKD) as determined from estimated glomerular filtration rate (eGFR) is recommended for risk prediction by current hypertension guidelines, the equations to derive eGFR may not perform well in black Africans. We compared whether across the adult lifespan, eGFR or CKD are as closely associated with noncardiac arterial vascular events, as carotid intima–media thickness (IMT), in Africa. Methods: In 1152 black South Africans [480 with noncardiac arterial events (294 with critical lower limb ischemia, 186 with stroke) of which 37% were premature] and 672 age, sex and ethnicity-matche...
Source: Journal of Hypertension - March 1, 2019 Category: Cardiology Tags: ORIGINAL PAPERS: Kidney Source Type: research