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International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA) trial: Rationale and design
Conclusions ISCHEMIA will provide new scientific evidence regarding whether an invasive management strategy improves clinical outcomes when added to optimal medical therapy in patients with SIHD and moderate or severe ischemia.
Source: American Heart Journal - May 26, 2018 Category: Cardiology Source Type: research

Effects of withdrawing vs continuing renin-angiotensin blockers on incidence of acute kidney injury in patients with renal insufficiency undergoing cardiac catheterization: Results from the Angiotensin Converting Enzyme Inhibitor/Angiotensin Receptor Blocker and Contrast Induced Nephropathy in Patients Receiving Cardiac Catheterization (CAPTAIN) trial
Conclusion In this pilot study of patients with moderate renal insufficiency undergoing cardiac catheterization, with-holding ACEI/ARB resulted in a non-significant reduction in contrast-induced AKI and a significant reduction in post-procedural rise of creatinine. This low cost intervention could be considered when referring a patient for cardiac catheterization.
Source: American Heart Journal - May 12, 2015 Category: Cardiology Source Type: research

Effects of Withdrawing Versus Continuing Renin-Angiotensin Blockers on Incidence of Acute Kidney Injury in Patients with Renal Insufficiency Undergoing Cardiac Catheterization: Results from the CAPTAIN Trial
Conclusion In patients with moderate renal insufficiency undergoing cardiac catheterization, withholding ACEI/ARB reduced (without statistical significance) the incidence of contrast-induced AKI. Additionally, a lower rise in post procedural creatinine levels was also noted. This low cost intervention could be considered when referring a patient for cardiac catheterization.
Source: American Heart Journal - April 22, 2015 Category: Cardiology Source Type: research

Sex differences in clinical outcomes in patients with stable angina and no obstructive coronary artery disease
Conclusions: Women with stable angina and nonobstructive CAD are 3 times more likely to experience a cardiac event within the first year of cardiac catheterization than men. A prospective trial to examine the impact of medical therapy on MACE in patients with nonobstructive CAD is warranted.
Source: American Heart Journal - May 1, 2013 Category: Cardiology Authors: Tara L. Sedlak, May Lee, Mona Izadnegahdar, C. Noel Bairey Merz, Min Gao, Karin H. Humphries Tags: Acute Ischemic Heart Disease Source Type: research

Ischemic stroke associated with left cardiac catheterization: The importance of modifiable and non-modifiable risk factors
Background: Stroke associated with left cardiac catheterization is a devastating complication, and its incidence has not changed over the decades.We investigated the incidence, in-hospital outcomes and the modifiable and non-modifiable risk factors for periprocedural ischemic stroke.Methods: Our retrospective cohort study included all patients experiencing periprocedural ischemic stroke among the 24,500 patients who underwent left cardiac catheterization between January 2003 and October 2010. The case group was compared with a group of control patients randomly selected among those who underwent the procedure during this p...
Source: American Heart Journal - January 21, 2013 Category: Cardiology Authors: Batric Popovic, Sylvain Carillo, Nelly Agrinier, Charles Christophe, Christine Selton-Suty, Yves Juillière, Etienne Aliot Tags: Interventional Cardiology Source Type: research