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Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

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Total 68 results found since Jan 2013.

U.S. trends in prescription nonsteroidal anti ‐inflammatory drug use among patients with cardiovascular disease, 1988–2016
ConclusionsPrescription NSAID use among patients with CVD appears to have declined from 1988 to 2016, primarily due to reduced COX ‐2‐selective inhibitor use. Nonetheless, the prevalence of prescription NSAIDs has persisted among a subset of high‐risk CVD populations.
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - January 9, 2021 Category: Drugs & Pharmacology Authors: Andrew Y. Hwang, Steven M. Smith Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

U.S. Trends in Prescription Nonsteroidal Anti ‐inflammatory Drug Use Among Patients with Cardiovascular Disease, 1988–2016
ConclusionsPrescription NSAID use among patients with CVD appears to have declined from 1988 to 2016, primarily due to reduced COX ‐2‐selective inhibitor use. Nonetheless, the prevalence of prescription NSAIDs has persisted among a subset of high‐risk CVD populations.
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - November 24, 2020 Category: Drugs & Pharmacology Authors: Andrew Y. Hwang, Steven M. Smith Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Use of Direct Oral Anticoagulants in Morbidly Obese Patients
AbstractIn 2016, the International Society on Thrombosis and Haemostasis (ISTH) published guidelines advising caution when using direct oral anticoagulants (DOACs) in patients with morbid obesity due to limited clinical efficacy and safety data supporting their use in this patient population. In this review, we analyzed published articles in the MEDLINE database (from inception through May 29, 2019), and the Cochrane Library, Google Scholar, and EMBASE databases (from inception through April 26, 2019) that evaluated morbidly obese patients with atrial fibrillation (AF) or venous thromboembolism (VTE) who received DOACs. A ...
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - December 12, 2019 Category: Drugs & Pharmacology Authors: Kazuhiko Kido, James C. Lee, Thaddaus Hellwig, Michael P. Gulseth Tags: REVIEW OF THERAPEUTICS Source Type: research

Oral Anticoagulant Prescription Trends, Profile Use, and Determinants of Adherence in Patients with Atrial Fibrillation
ConclusionThe clinical uptake of DOACs increased over time, accounting for 87.3% of prescriptions in 2017. In our study, 25% of new OAC users presented a low adherence level. Adherence to OACs remains a significant challenge in patients with AF.
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - November 21, 2019 Category: Drugs & Pharmacology Authors: Sylvie Perreault, Simon de Denus, Brian White ‐Guay, Robert Côté, Mireille E Schnitzer, Marie‐Pierre Dubé, Marc Dorais, Jean‐Claude Tardif Tags: ORIGINAL RESEARCH ARTICLE Source Type: research

Timing of Initiation of Oral Anticoagulation after Acute Ischemic Stroke in Patients with Atrial Fibrillation
AbstractPatients with atrial fibrillation (AF) who suffer an acute ischemic stroke are at risk for both hemorrhagic transformation and recurrent ischemic stroke in the acute post ‐stroke period. Oral anticoagulants are recommended for secondary stroke prevention in patients with AF. The optimal time to initiate anticoagulant therapy after acute ischemic stroke in patients with AF is uncertain. There is concern that early initiation increases the risk of hemorrhagic transfo rmation, whereas delayed initiation leaves the patient at risk for recurrent ischemic stroke. In this article, we provide a review of the risk of hemo...
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - November 6, 2019 Category: Drugs & Pharmacology Authors: Maureen A. Smythe, Dennis Parker, Candice L. Garwood, Adam Cuker, Steve R. Mess é Tags: REVIEW OF THERAPEUTICS Source Type: research

Critique of “Alteplase Therapy for Acute Ischemic Stroke in Pregnancy: Two Case Reports and a Systematic Review of the Literature”
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 39, Issue 8, Page 867-867, August 2019.
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - August 6, 2019 Category: Drugs & Pharmacology Authors: Ahmet Guner, Macit Kalcik, Mehmet Özkan Tags: Letter to the Editor Source Type: research

Alternative Viewpoint of “Alteplase Therapy for Acute Ischemic Stroke in Pregnancy: Two Case Reports and a Systematic Review of the Literature”
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 39, Issue 8, Page 866-866, August 2019.
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - August 6, 2019 Category: Drugs & Pharmacology Authors: Brian W. Gilbert, J. Spencer Dingman, Jacob A. Reeder, Amy L. Kiskaddon Tags: Letter to the Editor Source Type: research

Critique of “Alteplase Therapy for Acute Ischemic Stroke in Pregnancy: Two Case Reports and a Systematic Review of the Literature”
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 39, Issue 8, Page 867-867, August 2019.
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - August 6, 2019 Category: Drugs & Pharmacology Authors: Ahmet Guner, Macit Kalcik, Mehmet Özkan Tags: Letter to the Editor Source Type: research

Alternative Viewpoint of “Alteplase Therapy for Acute Ischemic Stroke in Pregnancy: Two Case Reports and a Systematic Review of the Literature”
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 39, Issue 8, Page 866-866, August 2019.
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - August 6, 2019 Category: Drugs & Pharmacology Authors: Brian W. Gilbert, J. Spencer Dingman, Jacob A. Reeder, Amy L. Kiskaddon Tags: Letter to the Editor Source Type: research

Comparative Effectiveness and Safety of Ticagrelor versus Prasugrel in Patients with Acute Coronary Syndrome: A Retrospective Cohort Analysis
ConclusionIn this population ‐based cohort of incident ACS patients, ticagrelor was associated with a reduced rate of recurrent nonfatal CVD events and major and minor bleeding events compared with prasugrel.This article is protected by copyright. All rights reserved.
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - July 21, 2019 Category: Drugs & Pharmacology Authors: Ghadeer K. Dawwas, Erich Dietrich, David Winchester, Almut G. Winterstein, Rich Segal, Haesuk Park Tags: Original Research Article Source Type: research

Alteplase Therapy for Acute Ischemic Stroke in Pregnancy: Two Case Reports and a Systematic Review of the Literature
This article is protected by copyright. All rights reserved.
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - May 10, 2019 Category: Drugs & Pharmacology Authors: Klayton M. Ryman, Wilson D. Pace, Shawn Smith, Gabriel V. Fontaine Tags: Review of Therapeutics Source Type: research