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Source: European Neurology
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Total 178 results found since Jan 2013.
A 3 ′ Untranslated Region Polymorphism of < b > < i > CTNNB1 < /i > < /b > (Rs2953) Alters MiR-3161 Binding and Affects the Risk of Ischemic Stroke and Coronary Artery Disease in Chinese Han Population
Conclusion: Polymorphism rs2953 is associated with the risk of both IS and CAD. Moreover, polymorphism rs2953 (T) introduces a binding site to miRNA-3161 and thus decreases luciferase activity in cell lines.Eur Neurol
Source: European Neurology - March 31, 2021 Category: Neurology Source Type: research
Prestroke Statins Improve Prognosis of Atrial Fibrillation-Associated Stroke through Increasing Suppressor of Cytokine Signaling-3 Levels
Conclusion: Our data suggested that the prestroke use of statins improved the clinical outcomes in AIS patients with AF by upregulating the level of SOCS-3 and reducing the plasma MMP-9 level.Eur Neurol
Source: European Neurology - March 8, 2021 Category: Neurology Source Type: research
Drip-and-Ship Model for Thrombectomy in Stroke Patients with Large-Vessel Occlusion
Conclusions: The “drip-and-ship” model has the potential to be a feasible model for patients with LVO in the anterior circulation to undergo endovascular treatment. Further large-scale prospective studies are warranted to confirm these findings.Eur Neurol
Source: European Neurology - March 5, 2021 Category: Neurology Source Type: research
Effect of Argatroban Injection on Clinical Efficacy in Patients with Acute Cerebral Infarction: Preliminary Findings
Conclusion: Argatroban injection is effective in the treatment of acute cerebral infarction, which can significantly improve the hemorheology of patients with good safety.Eur Neurol
Source: European Neurology - January 21, 2021 Category: Neurology Source Type: research
Association between Pre-Existing Coronary Artery Disease and 5-Year Mortality in Stroke Patients with High-Grade Carotid Artery Stenosis
Conclusion: Pre-existing CAD was associated with an increased risk of 5-year mortality in acute IS patients with high-grade CAS. Intensive treatment for the pre-existing CAD may reduce long-term mortality in acute IS patients with high-grade CAS.Eur Neurol
Source: European Neurology - December 23, 2020 Category: Neurology Source Type: research
Stroke Care in the First Affiliated Hospital of Chengdu Medical College during the COVID-19 Outbreak
Coronavirus disease-2019 (COVID-19) has become a pandemic disease globally. The First Affiliated Hospital of Chengdu Medical College has adopted telestroke to make stroke care accessible in remote areas. During the period January 2020 to March 2020, there was no COVID-19 case reported in our stroke center. A significant reduction of stroke admission was observed between the ischemic stroke group (235 vs. 588 cases) and the intracerebral hemorrhage group (136 vs. 150 cases) when compared with the same period last year (p #x3c; 0.001). The mean door-to-needle time (DNT) and door-to-puncture time (DPT) was 62 and 124 min, res...
Source: European Neurology - December 18, 2020 Category: Neurology Source Type: research
PREvention of VENous Thromboembolism in Hemorrhagic Stroke Patients – PREVENTIHS Study: A Randomized Controlled Trial and a Systematic Review and Meta-Analysis
Conclusions: In patients with acute ICH, the use of anticoagulants to prevent VTE was safe but the overall level of evidence was low due to the low number of patients included in randomized clinical trials.Eur Neurol
Source: European Neurology - November 13, 2020 Category: Neurology Source Type: research
Assessment of Patients with Intracerebral Hemorrhage or Hemorrhagic Transformation in the VENOST Study
Conclusion: CVST, an important cause of stroke in the young, should be monitored closely if the patients have additional symptoms of headache, multiple sinus involvement, and CH. Older age and parenchymal lesion, either hemorrhagic infarction or intracerebral hemorrhage, imply poor outcome.Eur Neurol
Source: European Neurology - October 30, 2020 Category: Neurology Source Type: research
Inhibition of LncRNA MALAT1 Attenuates Cerebral Ischemic Reperfusion Injury via Regulating AQP4 Expression
Stroke is one of the leading causes of mortality and disability worldwide. Long noncoding RNAs (lncRNAs) including MALAT1 have been shown to have critical roles in cerebral ischemia reperfusion injury (CIRI). However, the underlying mechanism of MALAT1 in CIRI has not been elucidated. The present study aimed to investigate the function and potential regulatory mechanism of MALAT1 in cerebral ischemic reperfusion injury. We established the middle cerebral artery occlusion (MCAO) model and oxygen-glucose deprivation/reoxygenation (OGD/RX) model in vivo and in vitro, and then Cell Counting Kit-8 (CCK-8), RT-qPCR, flow cytomet...
Source: European Neurology - October 30, 2020 Category: Neurology Source Type: research
Validation of the Simplified Modified Rankin Scale Questionnaire
Conclusion: Our results show good validity of the postal smRSq, answered by the patients, compared with the mRS carried out face-to-face at 6 months after a stroke. This result could help trialists in the future simplify study design and make multicentre trials and quality registers with a large number of patients more feasible and time-saving.Eur Neurol
Source: European Neurology - October 7, 2020 Category: Neurology Source Type: research
The Merging Tracks of Anosognosia and Neglect
Anosognosia and hemineglect are among the most startling neurological phenomena identified during the 20th century. Though both are associated with right hemisphere cerebral dysfunction, notably stroke, each disorder had its own distinct literature. Anosognosia, as coined by Babinski in 1914, describes patients who seem to have no idea of their paralysis, despite general cognitive preservation. Certain patients seem more than unaware, with apparent resistance to awareness. More extreme, and qualitatively distinct, is denial of hemiplegia. Various interpretations of pathogenesis are still deliberated. As accounts of its cap...
Source: European Neurology - September 14, 2020 Category: Neurology Source Type: research
Uncovering the Potential Differentially Expressed miRNAs and mRNAs in Ischemic Stroke Based on Integrated Analysis in the Gene Expression Omnibus Database
Conclusions: The identified differentially expressed miRNAs and mRNAs may be associated with the development of ischemic stroke.Eur Neurol
Source: European Neurology - September 9, 2020 Category: Neurology Source Type: research
Cerebral Venous Thrombosis: A Comprehensive Review
Conclusion: CSVT is a potentially fatal neurological condition that is often under-diagnosed due to its nonspecific presentation. Timely diagnosis and treatment can reduce morbidity and mortality, remarkably improving the outcome in affected individuals.Eur Neurol
Source: European Neurology - September 2, 2020 Category: Neurology Source Type: research
Classical Clinical and Neuroimaging Findings in SMART (Stroke-Like Migraine Attacks after Radiation Therapy) Syndrome
Eur Neurol
Source: European Neurology - August 31, 2020 Category: Neurology Source Type: research
Accelerated MR Evaluation of Patients with Suspected Large Arterial Vessel Occlusion: Diagnostic Performances of the FLAIR Vessel Hyperintensities
Conclusion: We found that FVH demonstrated excellent diagnostic performances for the identification of LVO and its level with good to excellent reproducibility. This MRI radio marker of occlusion provides additional arguments and may speed-up the detection of potential candidates for MT.Eur Neurol
Source: European Neurology - August 12, 2020 Category: Neurology Source Type: research
