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Prospective flow cytometry analysis of leucocyte subsets in critically ill patients who develop sepsis: a pilot study
ConclusionMonocyte counts and change of phenotype are associated with secondary sepsis occurrence in critically ill patients with injury.
Source: Infection - January 25, 2023 Category: Infectious Diseases Source Type: research

Cerebral Taenia crassiceps larvae infection in a 71-year-old immunocompetent male
We report a rare case of a cerebral infection withTaenia crassiceps tapeworm larvae in an immunocompetent 71-year-old German male. Initially, an intracerebral malignoma was suspected after the patient experienced stroke-like symptoms. After surgery, helminth larvae, later identified asT. crassiceps, were detected. Identification on the species level was possible by specific PCR and sequencing. After complete surgical removal, the patient was treated with albendazole and dexamethasone for two weeks. No residual symptoms were reported up to date.
Source: Infection - September 9, 2022 Category: Infectious Diseases Source Type: research

Infections causing stroke or stroke-like syndromes
ConclusionsStroke or stroke-like syndrome of infectious origin can be observed in an important proportion of case presenting with sensory-motor deficit of unknown origin; their accurate diagnosis has a considerable impact in terms of treatment choices and outcome.
Source: Infection - March 31, 2020 Category: Infectious Diseases Source Type: research

Left-sided infective endocarditis in persons who inject drugs
ConclusionsLSIE in PWID is not uncommon. Compared to non-LSIE in PWID, valve surgery is more common and mortality is higher. For reasons that are unclear, stroke is more frequent in LSIE in PWID than in non-PWID with LSIE but mortality is no different.
Source: Infection - February 24, 2020 Category: Infectious Diseases Source Type: research

Neuroinfections caused by fungi
ConclusionAlthough the number of fungal species causing CNS mycosis is increasing, only some possess well-defined treatment standards (e.g., cryptococcal meningitis and CNS aspergillosis). The early diagnosis of fungal infection, accompanied by identification of the etiological factor, is needed to allow the selection of effective therapy in patients with FIs-CNS and limit their high mortality.
Source: Infection - May 21, 2018 Category: Infectious Diseases Source Type: research

Fatal Neisseria macacae infective endocarditis: first report
We present here the first case ofN. macacae infective endocarditis in a 65-year-old man with a native aortic valve infection complicated by a peri-aortic abscess. N. macacae was isolated from blood culture and was found on the cardiac valve using 16S rDNA detection. Despite an appropriate antibiotic therapy, and aortic homograft replacement, and mitral repair, the patient died 4  days after surgery from a massive hemorrhagic stroke.
Source: Infection - January 27, 2017 Category: Infectious Diseases Source Type: research

Influence of chronic illnesses and underlying risk conditions on the incidence of pneumococcal pneumonia in older adults
Conclusion Our data support that nursing home residence, chronic pulmonary disease and immunocompromising conditions are the underlying conditions most strongly associated with an increasing risk of pneumococcal pneumonia in older adults. This data underline the need for better prevention strategies among these persons.
Source: Infection - June 3, 2015 Category: Infectious Diseases Source Type: research