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Quiz case: a clinical reasoning challenge in the emergency stroke setting
AbstractA right-handed woman in her 80s was admitted to the emergency department 1 h after sudden-onset global aphasia and right-sided hemiparesis. Medical history included arterial hypertension, dyslipidemia, hyperuricemia, aortic stenosis, osteoporosis, and recent pulmonary embolism. Medication consisted of apixaban, bisoprolol, hydrochlorothiazide, allopurinol, fenofibrate, and vitamin D. Vital parameters (blood pressure, heart rate, body temperature, oxygen saturation) and glycemia were all within normal range. Electrocardiogram showed a first-degree atrioventricular block. The patient was promptly transported to the e...
Source: Neurological Sciences - August 5, 2023 Category: Neurology Source Type: research

Acquired neurogenic foreign accent syndrome (ANFAS) as the sole outcome of the fibrinolysis procedure in a patient with acute stroke aphasia: a case study
Source: Neurological Sciences - December 26, 2022 Category: Neurology Source Type: research

Clinical and imaging predictors of dysphagia and swallowing ability recovery in acute ischemic stroke
ConclusionsInitial risk of aspiration was identified as risk factor for short-term and long-term dysphagia. Aphasia and larger WMH volume were revealed to be significant predictors for swallowing function recovery at 1  month. Right corona radiata was identified as an essential brain area for dysphagia.
Source: Neurological Sciences - October 27, 2022 Category: Neurology Source Type: research

Evaluation of rTMS in patients with poststroke aphasia: a systematic review and focused meta-analysis
ConclusionsThere are some strong studies evaluating the efficacy of rTMS in stroke patients but further research is required to fully establish the usefulness of this treatment. This meta-analysis indicates a clinically positive effect of rTMS with or without speech and language therapy (SLT) for patients with aphasia following stroke in overall language function and expressive language, including naming, repetition, writing, and comprehension. Low-frequency (1  Hz) rTMS over the unaffected hemisphere is effective and compatible with the concept of interhemispheric inhibition. Moreover, the treatment of 1 Hz rTMS for pat...
Source: Neurological Sciences - May 2, 2022 Category: Neurology Source Type: research

The effect of music therapy on language recovery in patients with aphasia after stroke: a systematic review and meta-analysis
ConclusionsMusic therapy can improve functional communication, repetition, and naming in patients with post-stroke aphasia, but did not significantly improve comprehension.Trial registrationCRD42021251526
Source: Neurological Sciences - November 24, 2021 Category: Neurology Source Type: research

Effects of virtual reality in post-stroke aphasia: a systematic review and meta-analysis
ConclusionThis review demonstrated a borderline positive clinical effect of VR for the severity of language impairment when compared with conventional rehabilitation therapy. Conversely, VR had no effect on functional communication, word finding, and repetition. Further research is warranted to reach more definite conclusions.
Source: Neurological Sciences - April 9, 2021 Category: Neurology Source Type: research

COVID-19 presenting with agraphia and conduction aphasia in a patient with left-hemisphere ischemic stroke
We report on LA, a patient who was affected by a left-hemisphere ischemic stroke, probably because of SARS-CoV-2. The patient showed a highly specific neuropsychological profile characterized by severe agraphia and some signs of conduction aphasia. All other cognitive and sensorimotor functions remained intact. We sustain that specific neuropsychological signs can be observed in patients with COVID-19. Therefore, in-depth and comprehensive neuropsychological assessment should be included to better explore and qualify the neuropsychological consequences of COVID-19. This is a new challenge for diagnosis and rehabilitation, ...
Source: Neurological Sciences - November 10, 2020 Category: Neurology Source Type: research

The assessment of severe lexical disorders in Italian individuals with aphasia
AbstractTests and batteries used in the evaluation of language impairments are overly complex and often ineffective (too difficult) in the assessment of post-stroke patients affected by severe aphasia (global aphasia). The present study reports details on the construction and standardization of a new Italian battery of tasks, specifically designed to assess severe lexical disorders in acquired aphasia (Battery for the Assessment of Severe Acquired Lexical Damage in Italian, BASALDI). The battery is composed of a common set of 64 stimuli (concrete nouns), belonging to both living and non-living categories, and consists of f...
Source: Neurological Sciences - February 11, 2020 Category: Neurology Source Type: research

“Accent issue”: foreign accent syndrome following ischemic stroke
In conclusion, FAS is a rare motor speech disorder, often related to cerebrovascular accidents involving critical regions in the dominant hemisphere. In addition, the present case adds further evidence to the role of the left primary motor cortex in modulation of prosody. In rare cases FAS can be the only sign of stroke or can appear after recovery from post-stroke aphasia.
Source: Neurological Sciences - October 28, 2019 Category: Neurology Source Type: research

The inter-rater reliability of the Italian version of Aphasia Rapid Test (ART) for acute ischemic stroke
ConclusionsThis study showed that the cross-cultural adaptation of the French version of the ART was successful in an Italian-speaking population.
Source: Neurological Sciences - September 14, 2019 Category: Neurology Source Type: research

Prognostic factors for long-term improvement from stroke-related aphasia with adequate linguistic rehabilitation
AbstractIn the past decade, several studies have reported potential prognostic factors for aphasia after stroke. However, these reports covered no more than 1  year after stroke onset, even though patients often continue to improve over longer periods. The present study included 121 patients with aphasia who received cognitive-based linguistic rehabilitation for at least 2 years post-onset. All were right-handed and had a lesion only in the left hemisph ere. Aphasia outcome was predicted using multiple linear regression analysis. Age at onset, lesion in the left superior temporal gyrus including Wernicke’s area, and ba...
Source: Neurological Sciences - June 9, 2019 Category: Neurology Source Type: research

The clinical management and rehabilitation of post stroke aphasia in Italy: evidences from the literature and clinical experience
AbstractAphasia is one of the most devastating symptoms in stroke survivors and severely affects patients ’ communication, quality of life, and social interactions. Several factors are critical to the prediction of aphasia recovery, including acute stroke management and subsequent language rehabilitation. A comprehensive assessment of language skills with appropriate instruments in different phases of post stroke months and years is needed in patients, in order to monitor their language improvement and to guide speech therapies over time. Beyond spontaneous recovery, the effects of speech and language therapy in terms of...
Source: Neurological Sciences - March 20, 2019 Category: Neurology Source Type: research