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Source: Neurology
Education: Education

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Total 259 results found since Jan 2013.

Teaching NeuroImages: Bilateral hypertrophic olivary degeneration following posterior circulation stroke
A 40-year-old comatose man was brought to the hospital with a history of posterior circulation stroke 4 months earlier due to hypertension. On examination, he had spastic quadriplegia, bilateral extensor plantar reflex, and palatal myoclonus. MRI revealed enlarged olives (figure 1) and chronic infarcts involving midbrain and pons (figure 2) suggestive of hypertrophic olivary degeneration seen after 4 months of insult. Hypertrophic olivary degeneration is a transsynaptic degeneration involving interconnecting fibers of inferior olivary nucleus, red nucleus, and contralateral dentate nucleus forming the 3 corners of the Guil...
Source: Neurology - October 30, 2017 Category: Neurology Authors: Venkatesh, M., Prasad, V. R. S., Basha, S. U., Priya, G. H. J. Tags: MRI, Coma, All Cerebrovascular disease/Stroke, All Education, Infarction RESIDENT AND FELLOW SECTION Source Type: research

Association of metabolic syndrome and change in Unified Parkinson's Disease Rating Scale scores
Conclusions: Persons with Parkinson disease meeting modified criteria for metabolic syndrome experienced a greater increase in total UPDRS scores over time, mainly as a result of increases in motor scores, compared to those who did not. Further studies are needed to confirm this finding. ClinicalTrials.gov identifier: NCT00449865.
Source: Neurology - October 23, 2017 Category: Neurology Authors: Leehey, M., Luo, S., Sharma, S., Wills, A.-M. A., Bainbridge, J. L., Wong, P. S., Simon, D. K., Schneider, J., Zhang, Y., Perez, A., Dhall, R., Christine, C. W., Singer, C., Cambi, F., Boyd, J. T. Tags: All Medical/Systemic disease, Endocrine, Parkinson's disease/Parkinsonism ARTICLE Source Type: research

Teaching Video NeuroImages: My weeping patient: Avoiding the pitfalls of a functional diagnosis
A 54-year-old man presented with symptoms of a posterior circulation stroke. A right facial palsy and horizontal right end gaze nystagmus was noted. On resolution, episodes of uncontrolled weeping without a provoking stimulus was observed (video at Neurology.org). These were initially unremitting, lasting minutes, with complete resolution after 1 month. An early consideration was of a functional neurologic disorder. Subsequent MRI brain demonstrated bilateral anterior pontine infarcts (figure). It has been hypothesized that pseudobulbar affect (PBA) results from the loss of frontal cortex input to the cerebellum during emo...
Source: Neurology - October 16, 2017 Category: Neurology Authors: Peters, J., Vijiaratnam, N., Wijeratne, T. Tags: All Cerebrovascular disease/Stroke, All Education RESIDENT AND FELLOW SECTION Source Type: research

Comparison of symptomatic and asymptomatic persons with primary age-related tauopathy
Conclusions: These findings support the hypothesis that participants with PART have an amyloid-independent dementing Alzheimer disease–like temporal lobe tauopathy.
Source: Neurology - October 16, 2017 Category: Neurology Authors: Besser, L. M., Crary, J. F., Mock, C., Kukull, W. A. Tags: All Clinical Neurology, Prognosis, Depression, All Cognitive Disorders/Dementia, Cognitive aging ARTICLE Source Type: research

Teaching NeuroImages: Wallerian degeneration in evolving pediatric stroke
An 8-year-old girl presented with acute hemiparesis and facial palsy. MRI demonstrated right middle cerebral artery territory infarction (figure, A and B), secondary to traumatic dissection. Following discharge, multiple visits for nonspecific neurologic symptoms prompted repeat short-term imaging, initially concerning for right midbrain infarction (figure, C–H).
Source: Neurology - September 25, 2017 Category: Neurology Authors: Jimenez-Gomez, A., Stowe, R. C. Tags: Childhood stroke, MRI, DWI, Other Education RESIDENT AND FELLOW SECTION Source Type: research

Association of parathyroid hormone with 20-year cognitive decline: The ARIC study
Conclusions: Our work does not support an independent influence of PTH on cognitive decline in this population-based cohort study.
Source: Neurology - August 28, 2017 Category: Neurology Authors: Kim, S. M., Zhao, D., Schneider, A. L. C., Korada, S. K., Lutsey, P. L., Guallar, E., Alonso, A., Windham, B. G., Gottesman, R. F., Michos, E. D. Tags: Endocrine, Cognitive aging, Cohort studies, Risk factors in epidemiology ARTICLE Source Type: research

Structural MRI markers of brain aging early after ischemic stroke
Conclusions: Brain structure is likely to be compromised before ischemic stroke by vascular risk factors. Smaller hippocampal and total brain volumes and increased WMH load represent proxies for underlying vascular brain injury.
Source: Neurology - July 10, 2017 Category: Neurology Authors: Werden, E., Cumming, T., Li, Q., Bird, L., Veldsman, M., Pardoe, H. R., Jackson, G., Donnan, G. A., Brodtmann, A. Tags: MRI, All Cerebrovascular disease/Stroke, Clinical trials Observational study (Cohort, Case control), Alzheimer's disease, Vascular dementia ARTICLE Source Type: research

A rare cause of stroke in young: PHACE syndrome (P1.253)
Conclusions:Neurocutaneous syndromes are typically diagnosed in childhood and can be a rare cause of stroke in young. Our patient suffered an ischemic stroke secondary to sequelae of undiagnosed PHACE syndrome. Early identification of neurocutaneous syndromes allows for proper surveillance, evaluation, and preventative education for development of complications.Disclosure: Dr. Fitzgerald has nothing to disclose. Dr. Chandra has nothing to disclose. Dr. Dannenbaum has nothing to disclose. Dr. Sharrief has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Fitzgerald, K., Chandra, S., Dannenbaum, M., Sharrief, A. Tags: Genetic Stroke Syndromes, Biomarkers, and Translational/Basic Research Source Type: research

Walk-in versus ems-prenotified stroke codes-time targets in a comprehensive stroke center (p1.271)
Conclusions:Walk-in strokes had significant delay in LKW to arrival, highlighting the need for community education in recognizing symptoms of stroke. People with larger strokes(higher NIHSS) tend to present via EMS. Significant delays in door to CT and stroke-code in walk-in strokes, demonstrates need for early stroke symptom recognition in the ER. EMS education and pre-notification improves likelihood of tPA administration.Disclosure: Dr. Kaur has nothing to disclose. Dr. Gudlavalleti has nothing to disclose. Dr. Schleier has nothing to disclose. Dr. Vallelunga has nothing to disclose. Dr. Onyan has nothing to disclose. D...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Kaur, G., Gudlavalleti, A., Schleier, J., Vallelunga, M., Onyan, J., Latorre, J. Tags: Pre-Hospital Stroke, Tele-Stroke, and mHealth Source Type: research

Feasibility of Google Glass for Remote Resident Supervision and Evaluation (P1.039)
Conclusions:This pilot feasibility study is a first step in applying mobile telemedicine using GG for remote supervision and evaluation of neurology residents. Early experiences suggest good technical feasibility and patient acceptance. Primary outcome analysis of inter-rater agreement between in-person and remote (GG) evaluation of the NIHSS and NEX assessments is pending.Study Supported by: This study receives support from an American Academy of Neurology Education Grant, as well as from an American Board of Psychiatry and Neurology Faculty Fellowship Award.Disclosure: Dr. Carrera has nothing to disclose. Dr. Chiota-McCo...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Carrera, J., Chiota-McCollum, N., Mantri, S., Clark, W., Wang, C., Odell, V., Berthaud, J., Gunnell, B., McMurry, T., Worrall, B., Southerland, A. Tags: Graduate Medical Education Research Source Type: research

Non-Neurologist Self Assessment of Emergency Neurology Proficiency and Interest in a Novel Intensive Stroke and Neurocritical Care Training Program: The X-CHANGE Program (P1.045)
Conclusions:Hospital based non-neurology physicians have significant exposure to critically ill neurological patients. Many are not comfortable with important fundamental skills, such as the neurological exam. There is strong interest in a proposed intensive training program emphasizing bedside teaching. Based upon these results, we are developing a formal intensive training program for practicing non -neurology physicians called the "Cross-disciplinary Cerebrovascular HospitAl NeuroloGy Education" program.Disclosure: Dr. Yee has nothing to disclose. Dr. Ke has nothing to disclose. Dr. Wong has nothing to disclose. Dr. Bar...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Yee, A., Ke, M., Wong, C., Barazangi, N., Tong, D., Chen, C. Tags: Graduate Medical Education Research Source Type: research

Bad News or Life Altering Diagnoses? Neurology Residents Attitudes towards Disclosing Diagnoses (P1.048)
Conclusions:How we perceive a diagnosis may be related to the language we use such as a diagnosis being called "bad news" versus "life altering."Study Supported by: Supported by a grant from the University Hospital Foundation, Edmonton, Alberta, CanadaDisclosure: Dr. Miyasaki has received research support from Allergan. . Dr. Bell has nothing to disclose. Dr. Hodgson has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Miyasaki, J., Bell, C., Hodgson, C. Tags: Graduate Medical Education Research Source Type: research

Simulation-Based Medical Education in Acute Neurologic Emergencies (P1.059)
Conclusions:Our data confirms the utility of SBME in acute neurologic disorders to improve resident confidence, clinical knowledge, teamwork, and communication skills. This experience allows us to improve future simulations by focusing on updated guidelines and a detailed analysis of resident performance.Disclosure: Dr. Ansari has nothing to disclose. Dr. Swor has nothing to disclose. Dr. Moreno has nothing to disclose. Dr. Park has nothing to disclose. Dr. Holder has nothing to disclose. Dr. Koo has nothing to disclose. Dr. Poblete has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Ansari, M., Swor, D., Moreno, G., Park, K., Holder, D., Koo, B., Poblete, R. Tags: Undergraduate Medical Education Research Source Type: research

Predictive Variables of Cognitive Dysfunction in Patients with Lupus (P1.340)
Conclusions:Duration of disease and low educational level are predictors of CD in patients with SLE. Depression and anxiety did not influence cognitive performance. Although cardiovascular comorbidity is a risk factor for dementia in general population, those variables might play a minor role in SLE patients.Study Supported by:Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES) and São Paulo Research Foundation (FAPESP) (grant #2015/08833-7) supported this study.Disclosure: Dr. Alessi has nothing to disclose. Dr. Dutra Antonio has nothing to disclose. Dr. Maria has nothing...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Alessi, H., Dutra, L. A., Maria, L., Xavier, P., Couce, P., Kayser, C., Barsottini, O. Tags: CNS Inflammatory Diseases and Differential Diagnosis I Source Type: research

Elevated cerebrospinal fluid total Tau levels reflects predominant cortical involvement in Alzheimers disease (P1.093)
Conclusions:Elevated CSF Tau levels in AD patients could be surrogate biomarker for AD subtypes with predominant early cortical symptoms and atrophy. There is a need for a systematic prospective unbiased follow-up to see if rapid clinical progression in AD is related to elevated T-Tau and distinct AD subtypes.Disclosure: Dr. Pillai has nothing to disclose. Dr. Khrestian has nothing to disclose. Dr. Bekris has nothing to disclose. Dr. Safar has nothing to disclose. Dr. Leverenz has received personal compensation for activities with Axovant, GE Healthcare and Navidea Biopharmaceuticals as a consultant.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Pillai, J., Khrestian, M., Bekris, L., Safar, J., Leverenz, J. Tags: Aging and Dementia: Biomarkers Source Type: research