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Source: Neurology
Condition: Hypertension

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Total 378 results found since Jan 2013.

N-terminal pro-brain natriuretic peptide and subclinical brain small vessel disease
Conclusions: NT-proBNP is independently associated with silent cerebrovascular lesions and could be a surrogate marker of vascular brain damage in hypertension.
Source: Neurology - December 11, 2016 Category: Neurology Authors: Vilar-Bergua, A., Riba-Llena, I., Penalba, A., Cruz, L. M., Jimenez-Balado, J., Montaner, J., Delgado, P. Tags: Stroke prevention, MRI ARTICLE Source Type: research

Increasing comorbidity and health services utilization in older adults with prior stroke
Conclusions: Our findings demonstrate the importance of community-based patient-centered care strategies for stroke survivors that address their range of health needs and prevent more costly acute care use.
Source: Neurology - November 13, 2016 Category: Neurology Authors: Gruneir, A., Griffith, L. E., Fisher, K., Panjwani, D., Gandhi, S., Sheng, L., Patterson, C., Gafni, A., Ploeg, J., Markle-Reid, M. Tags: All Health Services Research, All Cerebrovascular disease/Stroke ARTICLE Source Type: research

Clinical Reasoning: A case of subacute cognitive decline in a 76-year-old man
A 76-year-old, right-handed man presented to our emergency department with a 3-day history of cognitive decline following a motor vehicle collision. Medical history included hypertension, atrial fibrillation, and renal dysfunction. He was a high-functioning retired advertising executive who formerly smoked cigarettes, and used neither recreational drugs nor alcohol.
Source: Neurology - September 18, 2016 Category: Neurology Authors: MacLellan, A., Breiner, A., Tang-Wai, D. F., Casaubon, L. K. Tags: Other cerebrovascular disease/ Stroke, Clinical neurology history, Clinical neurology examination, All Cognitive Disorders/Dementia RESIDENT AND FELLOW SECTION Source Type: research

Hypertension prevention: In need of a grain of salt knowledge
Noncommunicable diseases (NCDs) are further deteriorating the health of populations in low-income settings, while those populations are still struggling with a substantial burden of infectious diseases.1,2 Therefore, research aimed at elucidating factors driving NCDs and identifying potential approaches to addressing the NCD burden in these regions is desperately needed. In a collaborative effort between Ugandan investigators and US researchers from Case Western and the University of Kentucky, Kaddumukasa et al.3 report important findings that may offer critical insights into the development of effective interventions for ...
Source: Neurology - September 18, 2016 Category: Neurology Authors: Birbeck, G. L., Sposato, L. A. Tags: All Cerebrovascular disease/Stroke, Case control studies EDITORIALS Source Type: research

Influence of sodium consumption and associated knowledge on poststroke hypertension in Uganda
Conclusions: High urine sodium and high salt-diet preferences were more frequent among poststroke hypertensive patients in Uganda than in their nonhypertensive counterparts. There was, however, no difference in dietary salt knowledge between these groups. The development of educational strategies that include salt-diet preferences may lead to better blood pressure control in this high-risk population.
Source: Neurology - September 18, 2016 Category: Neurology Authors: Kaddumukasa, M. N., Katabira, E., Sajatovic, M., Pundik, S., Kaddumukasa, M., Goldstein, L. B. Tags: All Cerebrovascular disease/Stroke, Case control studies ARTICLE Source Type: research

Circulating biomarkers and incident ischemic stroke in the Framingham Offspring Study
Conclusions: Higher levels of 4 biomarkers—CRP, tHcy, TNFR2, and VEGF—increased risk of IIS and improved the predictive ability of the Framingham Stroke Risk Profile score. Further research is warranted to explore their role as potential therapeutic targets.
Source: Neurology - September 18, 2016 Category: Neurology Authors: Shoamanesh, A., Preis, S. R., Beiser, A. S., Kase, C. S., Wolf, P. A., Vasan, R. S., Benjamin, E. J., Seshadri, S., Romero, J. R. Tags: Other cerebrovascular disease/ Stroke, All Cerebrovascular disease/Stroke, Cohort studies, Incidence studies, Infarction ARTICLE Source Type: research

Accelerated development of cerebral small vessel disease in young stroke patients
Conclusions: Patients with a young stroke have a higher burden of small vessel disease than controls adjusted for confounders. Cerebral aging seems accelerated by 10–20 years in these patients, which may suggest an increased vulnerability to vascular risk factors.
Source: Neurology - September 18, 2016 Category: Neurology Authors: Arntz, R. M., van den Broek, S. M. A., van Uden, I. W. M., Ghafoorian, M., Platel, B., Rutten-Jacobs, L. C. A., Maaijwee, N. A. M., Schaapsmeerders, P., Schoonderwaldt, H. C., van Dijk, E. J., de Leeuw, F.-E. Tags: Stroke in young adults, Prognosis ARTICLE Source Type: research

Teaching NeuroImages: Acute isolated oculomotor nerve palsy of microvascular origin
A 73-year-old man presented with acute-onset, right-sided ptosis and pain above the right eye. His medical history noted hypertension and diabetes. On physical examination, an isolated right oculomotor palsy was noted with preserved pupillary function. An MRI scan revealed isolated swelling of superior, inferior, and medial rectus muscle at the right side (figure). No cause other than presumed microvascular oculomotor nerve ischemia was shown.1 In patients aged 50 years or older, isolated ocular motor nerve palsies are most likely due to microvascular ischemia, but other etiologies such as aneurysm, brainstem stroke, and m...
Source: Neurology - August 14, 2016 Category: Neurology Authors: van den Wijngaard, I. R., Hagenbeek, R. E., Jellema, K., Lycklama a Nijeholt, G. J. Tags: MRI, Other cerebrovascular disease/ Stroke, All Clinical Neurology, Ocular motility RESIDENT AND FELLOW SECTION Source Type: research

Lifetime direct costs of stroke for indigenous patients adjusted for comorbidities
Conclusions: The costs of stroke for indigenous people and patients with different comorbidities are substantial and an integrated prevention strategy is needed.
Source: Neurology - July 31, 2016 Category: Neurology Authors: Zhao, Y., Condon, J., Lawton, P., He, V., Cadilhac, D. A. Tags: Cost effectiveness/economic, All Cerebrovascular disease/Stroke, Cohort studies ARTICLE Source Type: research

Sex differences exist after intracerebral hemorrhage but may not affect outcome
While differences by race/ethnicity and age are commonly evaluated, surprisingly few studies have focused on differences in risk factor and etiology for intracerebral hemorrhage (ICH).1 Epidemiologic data have identified important differences in risk factors for ICH, with hypertension strongly associated with nonlobar, deep ICH, while factors related to cerebral amyloid angiopathy (CAA) predominate for lobar ICH.2 In the current issue of Neurology®, Roquer et al.3 found that women were more likely to have lobar ICH than men, even after adjusting for age. Since men and women had similar proportions of diagnosed CAA, ICH...
Source: Neurology - July 17, 2016 Category: Neurology Authors: Woo, D., James, M. L. Tags: Natural history studies (prognosis), Intracerebral hemorrhage EDITORIALS Source Type: research

Lipid levels: A novel biomarker of impending intracerebral hemorrhage?
Despite many established behavioral and medical risk factors, such as smoking, hypertension, and atrial fibrillation, predicting which patients will develop a stroke and when it will occur remains vexing for clinicians and researchers alike. No matter how intuitive their existence, establishing more proximate triggers of stroke has proven quite difficult with some notable exceptions. One example of a known exogenous, environmental trigger is stimulant drugs that can cause cerebral vasospasm or acute hypertension leading to ischemic stroke or intracerebral hemorrhage (ICH).1 Another body of evidence supports the link betwee...
Source: Neurology - May 29, 2016 Category: Neurology Authors: Mendelson, S. J., Prabhakaran, S. Tags: Intracerebral hemorrhage EDITORIALS Source Type: research

Pearls & Oy-sters: Looking up the anatomy of looking up
A 46-year-old Chinese man with diabetes mellitus, hypertension, and hyperlipidemia, developed sudden onset of vertiginous dizziness and diplopia that was worse on looking up. His symptoms were not preceded by any antecedent infections, neither was there any headache. Blood pressure on arrival in the Emergency Department was 145/95 mm Hg and his neurologic examination revealed bilateral upward gaze restriction (video on the Neurology® Web site at Neurology.org). There was voluntary lid retraction by the patient. The pupils were 3 mm bilaterally and reactive to light and accommodation, there was no ptosis or nystagmus, a...
Source: Neurology - May 1, 2016 Category: Neurology Authors: Abid, M. B., Soon, D., Rathakrishnan, R., Zhao, P., Tan, C., Yeo, L. L. L. Tags: MRI, Clinical neurology examination, Ocular motility, Diplopia (double vision), All Cerebrovascular disease/Stroke RESIDENT AND FELLOW SECTION Source Type: research

Parakinesia Brachialis Oscitans after an Acute Internal Capsule Infarct (P1.014)
Conclusions:Involuntary stereotyped movements of an otherwise plegic arm while yawning was first observed in 1844 and coined "parakinesia brachialis oscitans" in 2010. The term parakinesia was used to differentiate the movements from synkinesia. The causes are diverse and include ischemic or hemorrhagic strokes, pontine tuberculoma, and amyotrophic lateral sclerosis. Ischemic strokes are most often implicated and typically involve a lenticulostriate branch of the middle cerebral artery. Lesions affecting the pyramidal tracts are the common denominator. The phenomenon may be observed acutely when the limb is flaccid or mont...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Koo, B., Wang, E. Tags: Movement Disorders ePoster Session Source Type: research

Restless legs syndrome associated with major diseases: A systematic review and new concept
Recent publications on both the genetics and environmental factors of restless legs syndrome (RLS) defined as a clinical disorder suggest that overlapping genetic risk factors may play a role in primary (idiopathic) and secondary (symptomatic) RLS. Following a systematic literature search of RLS associated with comorbidities, we identified an increased prevalence of RLS only in iron deficiency and kidney disease. In cardiovascular disease, arterial hypertension, diabetes, migraine, and Parkinson disease, the methodology of studies was poor, but an association might be possible. There is insufficient evidence for conditions...
Source: Neurology - April 3, 2016 Category: Neurology Authors: Trenkwalder, C., Allen, R., Hogl, B., Paulus, W., Winkelmann, J. Tags: Clinical trials Systematic review/meta analysis, Restless legs syndrome VIEWS & amp;amp; REVIEWS Source Type: research

Nursing Home Residents with Seizure Disorders/Epilepsy: Prevalence, Characteristics, and Treatment Patterns (P1.080)
Conclusions: NHRs with seizure disorder/epilepsy have substantial physical and cognitive impairment. Nearly half were prescribed combination AED therapy, and >20[percnt] took 蠅3 different AEDs, suggesting refractory epilepsy. Additional research is needed to assess treatment outcomes and further define optimal care in this population.Disclosure: Dr. Zarowitz has nothing to disclose. Dr. Allen has nothing to disclose. Dr. OShea has nothing to disclose. Dr. Wang has nothing to disclose. Dr. Semenchuk has nothing to disclose. Dr. Barghout has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Zarowitz, B., Allen, C., OShea, T., Wang, Z., Semenchuk, M., Barghout, V. Tags: Epilepsy/Clinical Neurophysiology: Geriatric Epilepsy, Epidemiology, and Health Services Source Type: research