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Source: BMC Neurology

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Total 724 results found since Jan 2013.

Factors for short-term outcomes in patients with a minor stroke: results from China National Stroke Registry
In this study, we aimed to identify which factors were associated with adverse outcomes of a minor stroke. Methods: The China National Stroke Registry (CNSR) is a nationwide prospective registry for patients presented to hospitals with acute cerebrovascular events between September 2007 and August 2008. The 3-month follow-up was completed in 4669 patients with a minor stroke defined as the initial neurological severity lower than 4 in the National Institutes of Health Stroke Scale (NIHSS). Multivariate model was used to determine the association between risk factors and clinical outcomes. Results: Of 4669 patients with a m...
Source: BMC Neurology - December 9, 2015 Category: Neurology Authors: Lingyun WuAnxin WangXianwei WangXingquan ZhaoChunxue WangLiping LiuHuaguang ZhengYongjun WangYibin CaoYilong Wangon behalf of the China National Stroke Registry investigators Source Type: research

Influences of hyperlipidemia history on stroke outcome; a retrospective cohort study based on the Kyoto Stroke Registry
Background: Although hyperlipidemia is known as a risk factor of stroke, its effects on the outcome are unknown. The aim of the study is to clarify the influences of hyperlipidemia on the stroke early outcome by estimating odds ratio (OR) for sequelae requiring care and hazard ratio (HR) for death. Methods: A total of 12617 stroke patients registered in the Kyoto Stroke Registry with information on a hyperlipidemia history. We compared patients who had hyperlipidemia history and patients who hadn’t. The OR for remaining sequelae requiring certain care on 30 day after stroke was calculated using a logistic regression in ...
Source: BMC Neurology - March 25, 2015 Category: Neurology Authors: Kazuo ShigematsuYoshiyuki WatanabeHiromi Nakanoon behalf of the Kyoto Stroke Registry Committee Source Type: research

Web-based tool for dynamic functional outcome after acute ischemic stroke and comparison with existing models
Background: Acute ischemic stroke (AIS) is one of the leading causes of death and adult disability worldwide. In the present study, we aimed to develop a web-based risk model for predicting dynamic functional status at discharge, 3-month, 6-month, and 1-year after acute ischemic stroke (Dynamic Functional Status after Acute Ischemic Stroke, DFS-AIS). Methods: The DFS-AIS was developed based on the China National Stroke Registry (CNSR), in which eligible patients were randomly divided into derivation (60%) and validation (40%) cohorts. Good functional outcome was defined as modified Rankin Scale (mRS) score???2 at discharge...
Source: BMC Neurology - November 25, 2014 Category: Neurology Authors: Ruijun JiWanliang DuHaipeng ShenYuesong PanPenglian WangGaifen LiuYilong WangHao LiXingquan ZhaoYongjun WangOn behalf of China National Stroke Registry (CNSR) investigators Source Type: research

5-year survival and rehospitalization due to stroke recurrence among patients with hemorrhagic or ischemic strokes in Singapore
Conclusions: Five year post-stroke survival and rehospitalization due to stroke recurrence as well as their associations with patient demographics were studied for different stroke types in Singapore. Specific preventive strategies are needed to target the high risk groups to improve their long-term outcomes after acute stroke.
Source: BMC Neurology - October 3, 2013 Category: Neurology Authors: Yan SunSze LeeBee HengVivien Chin Source Type: research

Ethnic differences in ischemic stroke subtypes in young-onset stroke: the Stroke Prevention in Young Adults Study
Conclusions: Our population-based data demonstrate ethnic differences in ischemic stroke subtypes. These findings may help clarify mechanisms of stroke in young adults which may in part be driven by ethnic-specific differences in early-onset traditional risk factors, thereby indicating differing emphasis on workup and prevention.
Source: BMC Neurology - October 29, 2015 Category: Neurology Authors: Megh TrivediKathleen RyanJohn Cole Source Type: research

Lipid management in the prevention of stroke: a meta-analysis of fibrates for stroke prevention
Conclusions: Our study indicated that fibrate therapy might play an important role in reducing the risk of fatal stroke in patients with previous diabetes, cardiovascular disease or stroke. However, it did not have an effect on the incidence of stroke.
Source: BMC Neurology - January 3, 2013 Category: Neurology Authors: Yu-Hao ZhouXiao-Fei YeFei-Fei YuXiao ZhangYing-Yi QinJian LuJia He Source Type: research

Risk factors, quality of care and prognosis in South Asian, East Asian and white patients with stroke
Conclusion: After stratification by stroke type, stroke care and outcomes are similar across ethnic groups in Ontario. Enhanced health promotion is needed to reduce delays to hospital for all ethnic groups.
Source: BMC Neurology - July 5, 2013 Category: Neurology Authors: Nadia KhanHude QuanMichael HillLouise PiloteFinlay McAlisterAnita PalepuBaiju ShahLimei ZhouHong ZhenMoira Kapral Source Type: research

Long-term outcome of vertebral artery origin stenosis in patients with acute ischemic stroke
Conclusions: Long-term outcomes of more than 50% stenosis of the VAO in patients with acute ischemic stroke were generally favorable. Additionally, ESRS was a predictor for the composite cardiovascular outcome. Asymptomatic VAO stenosis may not be a specific risk factor for recurrent ischemic stroke in the posterior circulation. However, VAO stenosis may require more clinical attention as a potential source of recurrent stroke when VAO stenosis is observed in patients who have concurrent ischemic stroke in the posterior circulation.
Source: BMC Neurology - November 11, 2013 Category: Neurology Authors: Young Jin KimJoon Hwa LeeJin Woo ChoiHong Gee RohYoung Il ChunJi-Sung LeeHahn Young Kim Source Type: research

Management of oral anticoagulation after cardioembolic stroke and stroke survival data from a population based stroke registry (LuSSt)
Conclusions: OAC non-treatment is the main predictor for stroke mortality. Although OAC initiation during hospital stay showed a trend towards higher mortality, early initiation in selected patients is an option as recommendation to start OAC post hospital was implemented in only 64.5%. This rate might be elevated by implementation of special intervention programs.
Source: BMC Neurology - October 8, 2014 Category: Neurology Authors: Frederick PalmMartin KrausAnton SaferJoachim WolfHeiko BecherArmin Grau Source Type: research

Impact of chronic inflammatory airway disease on stroke severity and long-term survival after ischemic stroke - a retrospective analysis
Conclusion: Co-existing CIAD showed no significant association with stroke severity at hospital admission and early mortality after ischemic stroke. CIAD was negatively associated with long-term survival after ischemic stroke.
Source: BMC Neurology - September 8, 2015 Category: Neurology Authors: Karl HaeuslerJuliane HermMaria KoniecznyUlrike GrittnerMitja LainscakMatthias EndresWolfram Doehner Source Type: research

Disease burden of stroke in rural South Africa: an estimate of incidence, mortality and disability adjusted life years
Conclusions: This study provides the first estimates of stroke burden in terms of incidence, and disability in rural South Africa. High YLL and DALYs lost amongst the rural populations demand urgent measures for preventing and mitigating impacts of stroke. Longitudinal surveillance sites provide a platform through which a changing stroke burden can be monitored in rural South Africa.
Source: BMC Neurology - April 12, 2015 Category: Neurology Authors: Mandy MaredzaMelanie BertramStephen Tollman Source Type: research

PRospective Observational POLIsh Study on post-stroke delirium (PROPOLIS): methodology of hospital-based cohort study on delirium prevalence, predictors and diagnostic tools
This study is designed to provide information on clinical manifestation, diagnostic methods and determinants of delirium spectrum disorders in acute stroke phase and their short and long-term consequences. Collected information allow us to create a predictive model for post-stroke delirium.
Source: BMC Neurology - June 19, 2015 Category: Neurology Authors: Elzbieta KlimiecTomasz DziedzicKatarzyna KowalskaAleksandra SzyperJoanna PeraPaulina PotoczekAgnieszka SlowikAleksandra Klimkowicz-Mrowiec Source Type: research

Cortical reorganisation of cerebral networks after childhood stroke: impact on outcome
This study will investigate functional reorganisation after paediatric arterial ischaemic stroke by means of resting state functional magnetic resonance imaging and transcranial magnetic stimulation in a cross-sectional plus longitudinal study design. The general aim of this study is to better understand neuroplasticity of the developing brain after stroke in order to develop more efficacious therapy and to improve the post-stroke functional outcome. Methods: The cross-sectional part of the study will investigate the functional cerebral networks of 35 children with chronic arterial ischaemic stroke (time of the lesion>2 y...
Source: BMC Neurology - June 10, 2015 Category: Neurology Authors: Salome KornfeldJuan Delgado RodríguezRegula EvertsAlain Kaelin-LangRoland WiestChristian WeisstannerPasquale MordasiniMaja SteinlinSebastian Grunt Source Type: research

Comparison of antiplatelet regimens in secondary stroke prevention: a nationwide cohort study
Conclusion: Clopidogrel and the combination of acetylsalicylic acid and dipyridamole were associated with similar risks for recurrent ischemic stroke and bleeding; whereas acetylsalicylic acid was associated with higher risks for both ischemic stroke and bleeding. The latter finding may partially be explained by selection bias.
Source: BMC Neurology - November 2, 2015 Category: Neurology Authors: Christine ChristiansenJannik PallisgaardThomas GerdsJonas OlesenMads JørgensenAnna NuméNicholas CarlsonSøren KristensenGunnar GislasonChristian Torp-Pedersen Source Type: research

Clinical significance of plasma VEGF value in ischemic stroke - research for biomarkers in ischemic stroke (REBIOS) study
Conclusions: Although plasma VEGF value increases immediately after the stroke onset equally in all stroke subtypes, its significance in functional outcome may be different among the stroke subtypes.
Source: BMC Neurology - April 8, 2013 Category: Neurology Authors: Ryu MatsuoTetsuro AgoMasahiro KamouchiJunya KurodaTakahiro KuwashiroJun HataHiroshi SugimoriKenji FukudaSeiji GotohNoriko MakiharaMasayo FukuharaHideto AwanoTetsu IsomuraKazuo SuzukiMasahiro YasakaYasushi OkadaYutaka KiyoharaTakanari Kitazono Source Type: research