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Source: BMC Neurology

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Total 724 results found since Jan 2013.

Use of vitamin K antagonists for secondary stroke prevention depends on the treating healthcare provider in Germany – results from the German AFNET registry
Conclusions: In the AFNET registry, anticoagulation for secondary stroke prevention was prescribed in roughly three-quarters of AF patients, a significantly higher rate than in primary prevention. We identified two factors associated with withholding oral anticoagulation in stroke survivors, namely higher age and—most prominently—treatment by a general practitioner/internist or physicians working at regional hospitals.
Source: BMC Neurology - August 5, 2015 Category: Neurology Authors: Karl HaeuslerAndrea GerthTobias LimbourgUlrich TebbeMichael OeffKarl WegscheiderAndrás TreszlUrsula RavensThomas MeinertzPaulus KirchhofGünter BreithardtGerhard SteinbeckMichael Nabaueron behalf of the AFNET registry investigators Source Type: research

HEart and BRain interfaces in Acute ischemic Stroke (HEBRAS) – rationale and design of a prospective oberservational cohort study
DiscussionBy comparing the results of routine diagnostic care to the study-specific MRI/ECG approach, the primary outcome of HEBRAS is the proportion of stroke patients with pathologic diagnostic findings. Predefined secondary outcomes are the association of stroke localization, autonomic dysbalance and cardiac dysfunction as well as the effect of impaired heart-rate-variability on long-term clinical outcome.The investigator-initiated HEBRAS study will assess whether an enhanced MRI approach and a prolonged ECG monitoring yield a higher rate of pathological findings than current standard diagnostic care to determine stroke...
Source: BMC Neurology - October 22, 2015 Category: Neurology Authors: Karl HaeuslerUlrike GrittnerJochen FiebachMatthias EndresThomas KrauseChristian Nolte Source Type: research

Speech disturbance at stroke onset is correlated with stroke early mortality
Background: Speech disturbance is a common symptom of stroke and is important as a prompt identifier of the event. The frequency of the symptom among each stroke subtype, differences between patients with and without speech disturbance and its correlation to early mortality remain unclear. Methods: The Kyoto prefecture of Japan has established a registry to enroll new stroke patients in cooperation with the Kyoto Medical Association and its affiliated hospitals. It is named the Kyoto Stroke Registry (KSR). We confirmed the existence or absence of speech disturbance in 1693 stroke patients registered to the KSR and investig...
Source: BMC Neurology - July 15, 2013 Category: Neurology Authors: Kazuo ShigematsuHiromi NakanoYoshiyuki WatanabeTatsuyuki SekimotoKouichiro ShimizuAkihiko NishizawaAtsushi OkumuraMasahiro Makino Source Type: research

Incidence of first ever stroke during Hajj ceremony
Conclusion: The first ever stroke rate among Iranian Hajj pilgrims was lower than that of the general population in Mashhad, Iran, except for females 35--44 or more than 75 years old. The number of events occurring during the Hajj suggests that Islamic countries should consider designing preventive and screening programs for pilgrims.
Source: BMC Neurology - December 5, 2013 Category: Neurology Authors: Mahmoud AzarpazhoohReza ShahripourMoira KapralNaghmeh MokhberAli ShoeibiMohammad FarzadfardMohammad RafatiAmanda ThriftNegar MorovatdarSeyed SajediAmir Azarpazhooh Source Type: research

Lessons from everyday stroke care for clinical research and vice versa: comparison of a comprehensive and a research population of young stroke patients
Conclusions: The comparison of baseline characteristics between the sifap1 study and the GQH registry revealed differences mainly determined by age.
Source: BMC Neurology - March 7, 2014 Category: Neurology Authors: Christian TanislavUlrike GrittnerBjoern MisselwitzJungehuelsing JungehuelsingChristian EnzingerBettina von SarnowskiJukka PutaalaManfred KapsPater KroppArndt RolfsTurgut TatlisumakFranz FazekasEdwin KolodnyBo Norrving Source Type: research

Brainstem infarcts predict REM sleep behavior disorder in acute ischemic stroke
Conclusions: The results support the notion of a predominant role of brainstem injury in the development of RBD and suggest that patients with brainstem infarcts RBD should be evaluated by a clinical neurologist.
Source: BMC Neurology - April 23, 2014 Category: Neurology Authors: Wai TangDirk HermannYang ChenHua LiangXiang LiuWinnie ChuAnil AhujaJill AbrigoVincent MokGabor UngvariKa Wong Source Type: research

Depression and anxiety symptoms post-stroke/TIA: prevalence and associations in cross-sectional data from a regional stroke registry
We described cross-sectional prevalence of depression and anxiety symptoms using the Hospital Anxiety and Depression Scale (HADS). Data on clinical and demographic details was collected and univariable and multivariable analyses performed to describe associations with HADS scores. We examined those with a diagnosis of ‘stroke’ and ‘TIA’ as separate cohorts. Results: From 13,283 potentially eligible stroke patients in the registry, we had full HADS data on 4,079. Of the 3,584 potentially eligible TIA patients, we had full HADS data on 1,247 patients. Across the stroke cohort, 1181 (29%) had HADS anxiety scores sugge...
Source: BMC Neurology - October 1, 2014 Category: Neurology Authors: Niall BroomfieldTerence QuinnAzmil Abdul-RahimMatthew WaltersJonathan Evans Source Type: research

A study on the natural history of scanning behaviour in patients with visual field defects after stroke
DiscussionThe longitudinal comparison of patients who do and do not learn compensatory scanning techniques may reveal important prognostic markers of natural recovery. Importantly, it may also help to determine the most effective treatment window for visual rehabilitation.
Source: BMC Neurology - April 24, 2015 Category: Neurology Authors: Tobias LoetscherCelia ChenSophie WignallAndreas BullingSabrina HoppeOwen ChurchesNicole ThomasMichael NichollsAndrew Lee Source Type: research

The interactive effect of diabetes and central obesity on stroke: a prospective cohort study of inner Mongolians
Conclusions: The participants who were both diabetic and centrally obese had significantly higher risk for incident stroke than the combination of individuals who individually had either condition among Mongolian population. This study suggests that central obesity and diabetes act synergistically to increase the risk of stroke.
Source: BMC Neurology - April 28, 2015 Category: Neurology Authors: Jennifer OlofindayoHao PengYan LiuHongmei LiMingzhi ZhangAili WangYonghong Zhang Source Type: research

An investigation of cortical neuroplasticity following stroke in adults: is there evidence for a critical window for rehabilitation?
DiscussionThe data from this trial will clarify whether there is a critical window for neuroplastic change in the brain following stroke. If so, intensive rehabilitation during this period could be more effective, reducing long-term disability and the cost burden of stroke.
Source: BMC Neurology - July 11, 2015 Category: Neurology Authors: Michelle McDonnellSimon KoblarNick WardJohn RothwellBrenton HordacreMichael Ridding Source Type: research

Left atrial volumes and associated stroke subtypes
This study is a standardized review of 633 patients admitted to the stroke service of a tertiary care hospital following a standardized stroke investigation and management pathway. Stroke subtypes were characterized using the Causative Classification System, using the hospitals online radiologic archival system with CCS certified stroke investigators. Patients with two mechanisms were excluded. Results: Patients with cardioembolic stroke had a higher proportion of atrial fibrillation (p
Source: BMC Neurology - October 18, 2013 Category: Neurology Authors: Quratulain ShaikhBilal AhmedMaryam AhmedJamal MaharMasood AhmadAyesha AhmedFarzin MajeedFariha AliMaria KhanAyeesha Kamal Source Type: research

Study protocol: prediction of stroke associated infections by markers of autonomic control
DiscussionSince a general prophylactic antibiotic treatment after stroke is not recommended, results of this study could have essential implications for an early identification and hence, timely appropriate treating of stroke-induced infections.Trial registration: Pradiktoren fur die Sepsis - Pred Sep, German Clinical Trials Register: DRKS00003392.
Source: BMC Neurology - January 13, 2014 Category: Neurology Authors: Dirk BrämerHeike HoyerAlbrecht GüntherSamuel NowackFrank BrunkhorstOtto WitteDirk Hoyer Source Type: research

Prediction of outcome in patients with suspected acute ischaemic stroke with CT perfusion and CT angiography: the Dutch acute stroke trial (DUST) study protocol
This study will provide insight in the added prognostic value of CTP and CTA parameters in outcome prediction of acute stroke patients. The prediction models that will be developed in this study may help guide future treatment decisions in the acute stage of ischaemic stroke.
Source: BMC Neurology - February 25, 2014 Category: Neurology Authors: Tom van SeetersGeert Jan BiesselsIrene van der SchaafJan Willem DankbaarAlexander HorschMerel LuitseJoris NiestenWillem MaliL KappelleYolanda van der GraafBirgitta Velthuis Source Type: research

The efficacy and safety of cilostazol for the secondary prevention of ischemic stroke in acute and chronic phases in Asian population- an updated meta-analysis
Conclusion: Cilostazolprovided a protective effect in the secondary prevention of the chronic phase ofischemic stroke.
Source: BMC Neurology - December 20, 2014 Category: Neurology Authors: LiGen ShiJiaLi PuLiang XuJay MalaguitJianmin ZhangSheng Chen Source Type: research

Korean Stroke Cohort for functioning and rehabilitation (KOSCO): study rationale and protocol of a multi-centre prospective cohort study
This study is designed as a 10-year, longitudinal follow-up investigating the residual disabilities, activity limitations, and quality of life issues arising in patients suffering from first-ever stroke. The main objectives of this study are to identify the factors that influence residual disability and long-term quality of life. The secondary objectives of this study are to determine the risk of mortality and recurrent vascular events in patients with acute first-ever stroke. We will investigate longitudinal health behaviors and patterns of healthcare utilization, including stroke rehabilitation care. We will also investi...
Source: BMC Neurology - March 25, 2015 Category: Neurology Authors: Won ChangMin SohnJongmin LeeDeog KimSam-Gyu LeeYong-Il ShinGyung-Jae OhYang-Soo LeeMin JooEun HanYun-Hee Kim Source Type: research