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Yale neurologists identify consistent neuroinflammatory response in ICH patients
(Yale University) Understanding how the immune system responds to acute brain hemorrhage could open doors to identifying treatments for this devastating disease. However, up until now, there has been limited information on inflammation in the brain from human patients, especially during the first days after a hemorrhagic stroke.This led a team of researchers to partner with a large clinical trial of minimally-invasive surgery to tackle defining the human neuroinflammatory response in living patients.
Source: EurekAlert! - Medicine and Health - February 22, 2021 Category: International Medicine & Public Health Source Type: news

Seventeen genetic abnormalities that cause brain aneurysms
(Universit é de Gen è ve) Intracranial aneurysm is a dilation of a blood vessel forming a fragile pocket. Rupture results in extremely severe haemorrhage. In the framework of the International Stroke Genetics Consortium, a team led by the University of Geneva, the University Hospitals of Geneva and the University of Utrecht has examinated the genome of more than 10,000 people suffering from aneurysms. 17 genetic abnormalities have been identified, notably involved in the functioning of the vascular endothelium.
Source: EurekAlert! - Medicine and Health - December 7, 2020 Category: International Medicine & Public Health Source Type: news

Researchers report positive results for ReWalk ReStore exosuit in stroke rehabilitation
(Kessler Foundation) The trial determined the safety, reliability, and feasibility of the device in this stroke population. 'We found that the ReStore provided targeted assistance for plantarflexion and dorsiflexion of the paretic ankle, improving the gait pattern,' explained Dr. Nolan, senior research scientist in the Center for Mobility and Rehabilitation Engineering Research at Kessler Foundation. 'This is an important first step toward expanding options for rehabilitative care for the millions of individuals with mobility impairments caused by ischemic and hemorrhagic stroke.'
Source: EurekAlert! - Medicine and Health - September 9, 2020 Category: International Medicine & Public Health Source Type: news

Rate over time of stroke caused by brain bleeding
(JAMA Network) This observational study looked at the rate and risk factors of stroke caused by bleeding within the brain (intracerebral hemorrhage) between 1948 and 2016 among 10,000 participants in the Framingham Heart Study. There have been conflicting results in other studies on whether the rate of this often deadly type of stroke is changing.
Source: EurekAlert! - Medicine and Health - June 8, 2020 Category: International Medicine & Public Health Source Type: news

Study ties stroke-related brain blood vessel abnormality to gut bacteria
(NIH/National Institute of Neurological Disorders and Stroke) In a nationwide study, NIH funded researchers found that the presence of abnormal bundles of brittle blood vessels in the brain or spinal cord, called cavernous angiomas (CA), are linked to the composition of a person's gut bacteria. Also known as cerebral cavernous malformations, these lesions which contain slow moving or stagnant blood, can often cause hemorrhagic strokes, seizures, or headaches.
Source: EurekAlert! - Medicine and Health - June 3, 2020 Category: International Medicine & Public Health Source Type: news

Reducing inflammation boosts cognitive recovery after stroke, may extend treatment window
(Medical University of South Carolina) Reperfusion therapy, the gold standard in stroke treatment, returns blood flow to the affected brain area and must be administered within four hours of stroke to minimize hemorrhage risk. Even with successful return of blood flow, full brain function recovery is rare. Medical University of South Carolina researchers have shown in a preclinical stroke model that adding a unique compound to reduce brain inflammation significantly improves cognitive recovery and extends the treatment window.
Source: EurekAlert! - Medicine and Health - June 1, 2020 Category: International Medicine & Public Health Source Type: news

Researchers examine data to identify optimal vasopressor treatment for rare type of stroke
(University of Texas Health Science Center at Houston) Results of an Electronic Health Record (EHR) study assessing the most commonly used medications for raising blood pressure in patients with nontraumatic subarachnoid hemorrhage (SAH), a rare type of stroke, have been published in Neurosurgical Focus by scientists at The University of Texas Health Science Center at Houston (UTHealth).
Source: EurekAlert! - Medicine and Health - May 29, 2020 Category: International Medicine & Public Health Source Type: news

Study of 418,000 Europeans finds different foods linked to different types of stroke
(European Society of Cardiology) Different types of food are linked to risks of different types of stroke, according to the largest study to investigate this, published in the European Heart Journal. The study of more than 418,000 people in nine European countries investigated ischaemic stroke and haemorrhagic stroke separately.
Source: EurekAlert! - Medicine and Health - February 23, 2020 Category: International Medicine & Public Health Source Type: news

Stroke drug boosts stem cell therapy for spinal cord injury in rats
(University of California - San Diego) In a UC San Diego study, rats with spinal cord injuries experienced a three-fold increase in motor activity when treated with neural progenitor cells that had been pre-conditioned with a modified form of tPA, a drug commonly used to treat non-hemorrhagic stroke.
Source: EurekAlert! - Medicine and Health - December 17, 2019 Category: International Medicine & Public Health Source Type: news

Removing more blood via minimally invasive surgery more likely to improve hemorrhagic stroke recover
(American Heart Association) The greater the volume of blood removed from the brain via minimally invasive surgery after a hemorrhagic stroke the greater the odds of better functional recovery.
Source: EurekAlert! - Medicine and Health - February 7, 2019 Category: International Medicine & Public Health Source Type: news

Draining blood from bleeding stroke may prevent death
(American Heart Association) A minimally invasive surgery combining the use of a clot-busting drug and a catheter to drain blood from the brain of hemorrhagic stroke patients reduced swelling and improved patients' prognoses, according to preliminary research.
Source: EurekAlert! - Medicine and Health - January 30, 2019 Category: International Medicine & Public Health Source Type: news

Drug to treat bleeding may benefit some stroke patients, study finds
(University of Nottingham) Patients with stroke caused by bleeding on the brain (intracerebral hemorrhage) may benefit from receiving a drug currently used to treat blood loss from major trauma and bleeding after childbirth, an international trial has revealed.
Source: EurekAlert! - Medicine and Health - May 16, 2018 Category: International Medicine & Public Health Source Type: news

First-of-its-kind study associates obesity with poorer stroke outcomes in non-white patients
(Louisiana State University Health Sciences Center) Research led by LSU Health New Orleans faculty has found that obesity contributed to poorer outcomes in non-white patients who had hemorrhagic strokes. It is one of the few studies examining outcomes of patients with obesity following intracerebral haemorrhage (ICH) and is the first such study conducted within the stroke belt of the US with a racially diverse population.
Source: EurekAlert! - Medicine and Health - April 26, 2018 Category: International Medicine & Public Health Source Type: news

The American Stroke Association receives $11.1 million gift from the Henrietta B. and Frederick H. Bugher Foundation to fund targeted research network in hemorrhagic stroke
(American Heart Association) The American Heart Association/American Stroke Association (AHA/ASA), the world's leading voluntary health organization devoted to fighting cardiovascular disease and stroke, announces its fifth major philanthropic gift from the Henrietta B. and Frederick H. Bugher Foundation.
Source: EurekAlert! - Medicine and Health - February 1, 2018 Category: International Medicine & Public Health Source Type: news

Immune cells may heal bleeding brain after strokes
(NIH/National Institute of Neurological Disorders and Stroke) By studying rodents, researchers showed that instead of attacking germs, some neutrophils may help heal the brain after an intracerebral hemorrhage, a form of stroke caused by ruptured blood vessels. The study suggests that two neutrophil-related proteins may play critical roles in protecting the brain from stroke-induced damage and could be used as treatments for intracerebral hemorrhage.
Source: EurekAlert! - Medicine and Health - September 20, 2017 Category: International Medicine & Public Health Source Type: news

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