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Femoral Access-Site Complications with Tenecteplase versus Alteplase before Mechanical Thrombectomy for Large-Vessel-Occlusion Stroke INTERVENTIONAL
CONCLUSIONS: Tenecteplase compared with alteplase before mechanical thrombectomy for large-vessel-occlusion stroke is not associated with an alteration in femoral access-site complication rates.
Source: American Journal of Neuroradiology - June 8, 2023 Category: Radiology Authors: Hendrix, P., Collins, M. K., Goren, O., Weiner, G. M., Dalal, S. S., Melamed, I., Kole, M. J., Griessenauer, C. J., Noto, A., Schirmer, C. M. Tags: INTERVENTIONAL Source Type: research

Infarct Evolution in Patients with Anterior Circulation Large-Vessel Occlusion Randomized to IV Alteplase and Endovascular Treatment versus Endovascular Treatment Alone INTERVENTIONAL
CONCLUSIONS: No statistically significant difference in infarct evolution was found in directly admitted patients who received IV alteplase and endovascular treatment within 4.5 hours of symptom onset versus patients who underwent endovascular treatment alone. Collateral status and occlusion location may be useful predictors of infarct evolution prognosis in patients eligible for IV alteplase who underwent endovascular treatment.
Source: American Journal of Neuroradiology - April 10, 2023 Category: Radiology Authors: Hoving, J. W., van Voorst, H., Kappelhof, M., Tolhuisen, M., Treurniet, K. M., LeCouffe, N. E., Rinkel, L. A., Koopman, M. S., Cavalcante, F., Konduri, P. R., van den Wijngaard, I. R., Ghariq, E., Anton Meijer, F. J., Coutinho, J. M., Marquering, H. A., R Tags: INTERVENTIONAL Source Type: research

How Do Physicians Approach Intravenous Alteplase Treatment in Patients with Acute Ischemic Stroke Who Are Eligible for Intravenous Alteplase and Endovascular Therapy? Insights from UNMASK-EVT INTERVENTIONAL
CONCLUSIONS: In patients eligible for endovascular therapy and intravenous alteplase, we observed a slightly lower decision rate in favor of intravenous alteplase under assumed ideal conditions compared with the decision rate under current local resources.
Source: American Journal of Neuroradiology - February 11, 2020 Category: Radiology Authors: Ospel, J. M., Kashani, N., Fischer, U., Menon, B. K., Almekhlafi, M., Wilson, A. T., Foss, M. M., Saposnik, G., Goyal, M., Hill, M. D. Tags: INTERVENTIONAL Source Type: research

Radiomics-Based Intracranial Thrombus Features on CT and CTA Predict Recanalization with Intravenous Alteplase in Patients with Acute Ischemic Stroke FUNCTIONAL
CONCLUSIONS: Thrombus radiomics features derived from NCCT and CTA are more predictive of recanalization with IV alteplase in patients with acute ischemic stroke with proximal occlusion than previously known thrombus imaging features such as length, volume, and permeability.
Source: American Journal of Neuroradiology - January 11, 2019 Category: Radiology Authors: Qiu, W., Kuang, H., Nair, J., Assis, Z., Najm, M., McDougall, C., McDougall, B., Chung, K., Wilson, A. T., Goyal, M., Hill, M. D., Demchuk, A. M., Menon, B. K. Tags: FUNCTIONAL Source Type: research