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Source: JAMA
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Total 276 results found since Jan 2013.
Cerebral Intraparenchymal Hemorrhage
This narrative review summarizes the pathophysiology, presentation, and management of patients with intraparenchymal hemorrhagic stroke, and approaches to poststroke rehabilitation, risk factor management, and anticoagulation.
Source: JAMA - April 2, 2019 Category: General Medicine Source Type: research
A Recent Study Linked Diet Soda With Stroke —But Is It Correlation or Causation?
This Medical News article is an interview with Yasmin Mossavar-Rahmani, PhD, RD, who studied the association of artificially sweetened beverages with cardiovascular disease and mortality in women.
Source: JAMA - April 23, 2019 Category: General Medicine Source Type: research
Listen to Your Heart: Alternate Strategies When Symptoms Don ’t Match the Diagnosis
In this narrative medicine essay, an infection diseases physician unconvinced of a stroke diagnosis listened to his own heart beat and accurately diagnosed mitral valve prolapse and reminds physicians to consider other possibilities when the symptoms don ’t line up with the diagnosis.
Source: JAMA - May 14, 2019 Category: General Medicine Source Type: research
Association Between Unrecognized OSA and Cardiovascular Events After Major Noncardiac Surgery
This cohort study assesses the association between unrecognized obstructive sleep apnea (OSA) and 30-day risk of cardiovascular complications (myocardial injury, cardiac death, heart failure, thromboembolism, atrial fibrillation, and stroke) among adults undergoing major noncardiac surgery.
Source: JAMA - May 14, 2019 Category: General Medicine Source Type: research
Prevalence and Payments for Traumatic Injury vs Common Acute Diseases in Medicare Beneficiaries
This study uses Medicare Parts A and B claims data to compare hospitalizations for and spending on traumatic injury vs heart failure, pneumonia, stroke, and acute myocardial infarction in older adults between 2008 and 2014.
Source: JAMA - June 4, 2019 Category: General Medicine Source Type: research
Synthesizing Speech From Brain Activity
Writing inNature, researchers at the University of California, San Francisco (UCSF) described a system that synthesizes intelligible speech from brain activity recorded during speaking or mimed speaking. Although theirstudy involved people without speech impairments, the technology could be a stepping stone toward restoring communication for people with stroke, amyotrophic lateral sclerosis, or other neurological disorders that impede speech, the researchers said.
Source: JAMA - June 11, 2019 Category: General Medicine Source Type: research
Glucose Control in the Perioperative Period —Reply
In Reply In response to Dr Finucane ’s query about our presentation on the risks and benefits of intensive glucose control, we would like to point out that we do not advocate intensive glucose control in the perioperative period. We have, in fact, alluded to studies showing the potential harm of intensive glucose control in the intr aoperative period, and throughout the Clinical Update, we advocated for a target blood glucose of less than 180 mg/dL and avoidance of hypoglycemia. Our comment that “good” (not intensive) glucose control is likely to be beneficial was based on a meta-analysis by Sathya et al, which showe...
Source: JAMA - July 2, 2019 Category: General Medicine Source Type: research
Glucose Control in the Perioperative Period
To the Editor Drs Simha and Shah provided a Clinical Update on perioperative glucose control in patients with diabetes undergoing elective surgery. They stated that “limited evidence suggests that good glucose control is likely to be beneficial in reducing postoperative mortality, length of hospital stay, and cardiovascular complications such as stroke.” In support, they cited a Cochrane Review.
Source: JAMA - July 2, 2019 Category: General Medicine Source Type: research
Blood Pressure and Dementia
Alzheimer disease and related dementias affect nearly 10% of US adults older than 65 years. With an aging population, the prevalence of dementia is likely to increase, adding to the enormous burden on affected patients, their caregivers, and the health care system. Besides Alzheimer pathology (eg, amyloid and tau protein deposition) in the brain, there is increasing evidence of the contributions of vascular pathology (eg, stroke, subclinical infarct, and ischemic white matter changes) on dementia occurrence. Furthermore, these 2 common pathologies can coexist in individual patients, with evidence that cerebrovascular insul...
Source: JAMA - August 13, 2019 Category: General Medicine Source Type: research
Trends in Cardiometabolic Mortality in the United States, 1999-2017
This study evaluates the Centers for Disease Control and Prevention ’s Wide-Ranging Online Data for Epidemiologic Research to compare trends in heart disease, stroke, diabetes, and hypertension mortality rates by race and sex from 1999 to 2017.
Source: JAMA - August 27, 2019 Category: General Medicine Source Type: research
Catheter Ablation Compared With Drug Therapy for Atrial Fibrillation
To the Editor Dr Packer and colleagues for the CABANA Investigators demonstrated no significant difference between catheter ablation and antiarrhythmic drug therapy in patients with paroxysmal and persistent atrial fibrillation on the composite primary end point of death, disabling stroke, serious bleeding, or cardiac arrest. For the composite secondary end point of death or CV hospitalization, patients randomized to catheter ablation had better event-free survival than those randomized to antiarrhythmic drugs.
Source: JAMA - September 17, 2019 Category: General Medicine Source Type: research
“Smoldering” Brain Lesions Might Signal Severe Multiple Sclerosis
Chronic active lesions in the brain might signal more aggressive and disabling forms of multiple sclerosis (MS), scientists from the National Institute of Neurological Disorders and Stroke (NINDS) recently reported in JAMA Neurology.
Source: JAMA - September 24, 2019 Category: General Medicine Source Type: research
General Anesthesia vs Procedural Sedation With Functional Outcome in Patients Undergoing Thrombectomy
This meta-analysis pools individual patient data to estimate the association between receipt of general anesthesia vs procedural sedation and 3-month disability among patients with acute ischemic stroke undergoing mechanical thrombectomy from 3 randomized trials.
Source: JAMA - October 1, 2019 Category: General Medicine Source Type: research
Incorrect Y-Axis Labels and Minor Data Errors
This article was corrected online.
Source: JAMA - November 5, 2019 Category: General Medicine Source Type: research
Treatment of Hyperglycemia in Patients With Acute Stroke —Reply
In Reply Dr Long and colleagues point out that the SHINE trial may have shown additional useful results if patients were stratified based on prestroke glycemic control. Although the sample of patients without diabetes was small, eFigure 1 in Supplement 3 in the article showed that there was no significant difference in the primary outcome by treatment group in the subgroups of patients with or without diabetes. We are in the process of conducting secondary analyses to assess hemoglobin A1c levels and outcome.
Source: JAMA - December 10, 2019 Category: General Medicine Source Type: research
