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Source: Heart
Condition: Heart Failure

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Total 92 results found since Jan 2013.

Systolic blood pressure, chronic obstructive pulmonary disease and cardiovascular risk
Conclusion Using deep learning for modelling EHR, we identified a monotonic association between SBP and risk of cardiovascular events in patients with COPD.
Source: Heart - July 27, 2023 Category: Cardiology Authors: Rao, S., Nazarzadeh, M., Li, Y., Canoy, D., Mamouei, M., Salimi-Khorshidi, G., Rahimi, K. Tags: Open access Cardiac risk factors and prevention Source Type: research

Heartbeat: prediction of atrial fibrillation risk
One of the challenges in prevention of stroke is identification of patients at risk of atrial fibrillation (AF) shortly before the onset of the arrhythmia so that prevention therapies can be promptly instituted. In this issue of Heart, Nadarajah and colleagues1 report the development and validation of an algorithm based on data from the UK Clinical Practice Research Datalink GOLD dataset that included 2 081 139 individuals of whom 7386 developed AF within 6 months. This new algorithm-- Future Innovations in Novel Detection of Atrial Fibrillation (FIND-AF) – identified a high-risk cohort with a 20-fold higher 6 month ...
Source: Heart - June 26, 2023 Category: Cardiology Authors: Otto, C. M. Tags: Highlights from this issue Source Type: research

Prediction of short-term atrial fibrillation risk using primary care electronic health records
Conclusions FIND-AF, a machine learning algorithm applicable at scale in routinely collected primary care data, identifies people at higher risk of short-term AF.
Source: Heart - June 26, 2023 Category: Cardiology Authors: Nadarajah, R., Wu, J., Hogg, D., Raveendra, K., Nakao, Y. M., Nakao, K., Arbel, R., Haim, M., Zahger, D., Parry, J., Bates, C., Cowan, C., Gale, C. P. Tags: Open access, Editor's choice Arrhythmias and sudden death Source Type: research

Incident cardiovascular events and imaging phenotypes in UK Biobank participants with past cancer
Conclusions Cancer history is linked to increased risk of incident CVDs and adverse cardiac remodelling independent of shared vascular risk factors.
Source: Heart - June 14, 2023 Category: Cardiology Authors: Raisi-Estabragh, Z., Cooper, J., McCracken, C., Crosbie, E. J., Walter, F. M., Manisty, C. H., Robson, J., Mamas, M. A., Harvey, N. C., Neubauer, S., Petersen, S. E. Tags: Open access, Editor's choice, Press releases Cardiac risk factors and prevention Source Type: research

Prevalence, outcomes and costs of a contemporary, multinational population with heart failure
Conclusions We estimate that 1–2% of the contemporary adult population has HF. These individuals are at significant risk of adverse outcomes and associated costs, predominantly driven by hospitalisations for HF or CKD. There is considerable public health potential in understanding the contemporary burden of HF and the importance of optimising its management.
Source: Heart - March 10, 2023 Category: Cardiology Authors: Norhammar, A., Bodegard, J., Vanderheyden, M., Tangri, N., Karasik, A., Maggioni, A. P., Sveen, K. A., Taveira-Gomes, T., Botana, M., Hunziker, L., Thuresson, M., Banerjee, A., Sundström, J., Bollmann, A. Tags: Open access, Press releases Heart failure and cardiomyopathies Source Type: research

Prediction of incident atrial fibrillation with cardiac biomarkers and left atrial volumes
Conclusions In the general population, echocardiographic left atrial volumetric indices and NT-proBNP, but not cTnT and GDF-15, associate with prevalent atrial fibrillation and with risk of incident atrial fibrillation. cTnT and NT-proBNP provide incremental prognostic information to echocardiography.
Source: Heart - February 14, 2023 Category: Cardiology Authors: Lyngbakken, M. N., Ronningen, P. S., Solberg, M. G., Berge, T., Brynildsen, J., Aagaard, E. N., Kvisvik, B., Rosjo, H., Steine, K., Tveit, A., Omland, T. Tags: Arrhythmias and sudden death Source Type: research

Emergent readmission and long-term mortality risk after incident atrial fibrillation hospitalisation
Conclusion This study highlights the large burden of unplanned all-cause and cardiovascular-specific readmissions within 2 years after being hospitalised for incident AF and their associated adverse impact on mortality. Concomitant comorbidities are independently associated with unplanned hospitalisations and mortality, which supports integrated multidisciplinary management of comorbidities, along with AF-targeted treatments, to improve long-term outcomes in patients with AF.
Source: Heart - February 14, 2023 Category: Cardiology Authors: Weber, C., Hung, J., Hickling, S., Li, I., Murray, K., Briffa, T. Tags: Cardiac risk factors and prevention Source Type: research

Early surgical intervention versus conservative management of asymptomatic severe aortic stenosis: a systematic review and meta-analysis
Conclusions This study suggests that for patients with asymptomatic severe AS an early surgical intervention compared with a conservative WW strategy was associated with a lower heart failure hospitalisation and a similar rate of stroke or myocardial infarction, although with significant risk of bias. PROSPERO registration number CRD42021291144.
Source: Heart - January 27, 2023 Category: Cardiology Authors: Costa, G. N. F., Cardoso, J. F. L., Oliveiros, B., Goncalves, L., Teixeira, R. Tags: Valvular heart disease Source Type: research

Outcomes and drivers of inappropriate dosing of non-vitamin K antagonist oral anticoagulants (NOACs) in patients with atrial fibrillation: a systematic review and meta-analysis
Conclusions Our analysis suggests that off-label underdosing of NOACs does not reduce bleeding outcomes. Patients prescribed off-label NOAC doses are at an increased risk of all-cause mortality. These data underscore the importance of prescriber adherence to NOAC dosing guidelines to achieve optimal clinical outcomes for patients with AF. PROSPERO registration number CRD42020219844.
Source: Heart - January 11, 2023 Category: Cardiology Authors: Caso, V., de Groot, J. R., Sanmartin Fernandez, M., Segura, T., Blomström-Lundqvist, C., Hargroves, D., Antoniou, S., Williams, H., Worsley, A., Harris, J., Caleyachetty, A., Vardar, B., Field, P., Ruff, C. T. Tags: Open access Systematic review Source Type: research

Heartbeat: hospitalisation for COVID-19 is associated with an increased risk of subsequent adverse cardiovascular events
In order to assess whether previous COVID-19 infection might be associated with a higher risk of subsequent adverse cardiovascular disease (CVD) events, Raisi-Estabragh and colleagues1 analysed incident CVD events in 17 871 UK Biobank cases with prospective follow-up from March 2020 to March 2021. Hospitalisation for COVID-19 was associated with an increased risk of several adverse CVD events, including myocardial infarction, stroke, heart failure, atrial fibrillation, venous thromboembolism and mortality (figure 1). Risk was highest in the first 30 days after infection, but remained higher than matched controls over an av...
Source: Heart - December 22, 2022 Category: Cardiology Authors: Otto, C. M. Tags: COVID-19 Highlights from this issue Source Type: research

Cardiovascular disease and mortality sequelae of COVID-19 in the UK Biobank
Conclusions Individuals hospitalised with COVID-19 have increased risk of incident cardiovascular events across a range of disease and mortality outcomes. The risk of most events is highest in the early postinfection period. Individuals not requiring hospitalisation have increased risk of VTE, but not of other cardiovascular-specific outcomes.
Source: Heart - December 22, 2022 Category: Cardiology Authors: Raisi-Estabragh, Z., Cooper, J., Salih, A., Raman, B., Lee, A. M., Neubauer, S., Harvey, N. C., Petersen, S. E. Tags: Open access, Editor's choice, Press releases, COVID-19 Cardiac risk factors and prevention Source Type: research

Transcatheter versus surgical closure of atrial septal defect in adult patients with tricuspid regurgitation
Conclusions While TAP was effective for the treatment of significant TR, transcatheter ASD closure also significantly reduced TR as well. Transcatheter ASD closure may be considered an alternative treatment option in patients with moderate or severe TR.
Source: Heart - November 24, 2022 Category: Cardiology Authors: Kim, M., Lee, P. H., Kim, D.-H., Jung, S.-H., Lee, S.-A., Lee, S., Kang, D.-H., Song, J.-K., Song, J.-M. Tags: Congenital heart disease Source Type: research

Eligibility for early rhythm control in patients with atrial fibrillation in the UK Biobank
Conclusion Around 80% of participants diagnosed with AF in the UK population are eligible for early rhythm-control. Early rhythm-control therapy was safe in routine care.
Source: Heart - November 10, 2022 Category: Cardiology Authors: Kany, S., Cardoso, V. R., Bravo, L., Williams, J. A., Schnabel, R., Fabritz, L., Gkoutos, G. V., Kirchhof, P. Tags: Open access Arrhythmias and sudden death Source Type: research

Proteomics profiling reveals a distinct high-risk molecular subtype of hypertrophic cardiomyopathy
Conclusions Our prospective plasma proteomics study not only exhibited the presence of HCM molecular subtypes but also identified pathobiological mechanisms associated with a distinct high-risk subtype of HCM.
Source: Heart - October 28, 2022 Category: Cardiology Authors: Liang, L. W., Raita, Y., Hasegawa, K., Fifer, M. A., Maurer, M. S., Reilly, M. P., Shimada, Y. J. Tags: Heart failure and cardiomyopathies Source Type: research

Exercise oxygen pulse kinetics in patients with hypertrophic cardiomyopathy
Conclusion None of the frequently used CPET parameters, either as absolute values or dynamic relationships, were associated with LVOTO. Differently, an abnormal temporal behaviour of O2-pulse during exercise, which is strongly related to inadequate SV increase, correlates with reduced functional capacity (peak and anaerobic threshold VO2 and workload) and increased VE/VCO2 slope, identifying more advanced disease irrespectively of LVOTO.
Source: Heart - September 26, 2022 Category: Cardiology Authors: Mapelli, M., Romani, S., Magri, D., Merlo, M., Cittar, M., Mase, M., Muratori, M., Gallo, G., Sclafani, M., Carriere, C., Zaffalon, D., Salvioni, E., Mattavelli, I., Vignati, C., De Martino, F., Rovai, S., Autore, C., Sinagra, G., Agostoni, P. Tags: Heart failure and cardiomyopathies Source Type: research