• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Incident cardiovascular events and imaging phenotypes in UK Biobank participants with past cancer
Conclusions Cancer history is linked to increased risk of incident CVDs and adverse cardiac remodelling independent of shared vascular risk factors.
Source: Heart - June 14, 2023 Category: Cardiology Authors: Raisi-Estabragh, Z., Cooper, J., McCracken, C., Crosbie, E. J., Walter, F. M., Manisty, C. H., Robson, J., Mamas, M. A., Harvey, N. C., Neubauer, S., Petersen, S. E. Tags: Open access, Editor's choice, Press releases Cardiac risk factors and prevention Source Type: research

Proteomics profiling reveals a distinct high-risk molecular subtype of hypertrophic cardiomyopathy
Conclusions Our prospective plasma proteomics study not only exhibited the presence of HCM molecular subtypes but also identified pathobiological mechanisms associated with a distinct high-risk subtype of HCM.
Source: Heart - October 28, 2022 Category: Cardiology Authors: Liang, L. W., Raita, Y., Hasegawa, K., Fifer, M. A., Maurer, M. S., Reilly, M. P., Shimada, Y. J. Tags: Heart failure and cardiomyopathies Source Type: research

Exercise oxygen pulse kinetics in patients with hypertrophic cardiomyopathy
Conclusion None of the frequently used CPET parameters, either as absolute values or dynamic relationships, were associated with LVOTO. Differently, an abnormal temporal behaviour of O2-pulse during exercise, which is strongly related to inadequate SV increase, correlates with reduced functional capacity (peak and anaerobic threshold VO2 and workload) and increased VE/VCO2 slope, identifying more advanced disease irrespectively of LVOTO.
Source: Heart - September 26, 2022 Category: Cardiology Authors: Mapelli, M., Romani, S., Magri, D., Merlo, M., Cittar, M., Mase, M., Muratori, M., Gallo, G., Sclafani, M., Carriere, C., Zaffalon, D., Salvioni, E., Mattavelli, I., Vignati, C., De Martino, F., Rovai, S., Autore, C., Sinagra, G., Agostoni, P. Tags: Heart failure and cardiomyopathies Source Type: research

Pregnancy-related cardiovascular conditions and outcomes in a United States Medicaid population
Conclusion This US cohort of Medicaid-funded women have a high incidence of severe cardiovascular conditions during pregnancy. Cardiometabolic conditions of pregnancy conferred threefold higher odds of severe cardiovascular outcomes.
Source: Heart - September 12, 2022 Category: Cardiology Authors: Marschner, S., von Huben, A., Zaman, S., Reynolds, H. R., Lee, V., Choudhary, P., Mehta, L. S., Chow, C. K. Tags: Open access, Editor's choice Cardiac risk factors and prevention Source Type: research

Heartbeat: cardiovascular maternal health and disparities in clinical outcomes
Cardiovascular disease continues to account for a high proportion of pregnancy-related deaths in women in the USA. In addition to pre-existing heart disease, gestational hypertension and diabetes, as well as pre-eclampsia and eclampsia, are associated with an increased risk of adverse cardiovascular outcomes both in the short and long-term. In this issue of Heart, Marschner and colleagues1 report an incidence of cardiometabolic conditions (hypertensive disease and diabetes) of 224.3 (95% CI 221.3 to 227.3) per 1000 births among 74 510 women, mean age 26.4 years (SD 5.5) in a cross-sectional study of Medicare patients from ...
Source: Heart - September 12, 2022 Category: Cardiology Authors: Otto, C. M. Tags: Highlights from this issue Source Type: research

Relationship between aetiology and left ventricular systolic dysfunction in hypertrophic cardiomyopathy
Conclusions In adults with HCM, LV systolic dysfunction is more frequent in those with rare phenocopies. When combined with age at presentation, it is a marker for specific aetiologies and is associated with poorer long-term survival.
Source: Heart - January 26, 2017 Category: Cardiology Authors: Rosmini, S., Biagini, E., O'Mahony, C., Bulluck, H., Ruozi, N., Lopes, L. R., Guttmann, O., Reant, P., Quarta, C. C., Pantazis, A., Tome-Esteban, M., Mckenna, W. J., Rapezzi, C., Elliott, P. M. Tags: Hypertrophic cardiomyopathy, Drugs: cardiovascular system, Echocardiography, Interventional cardiology, Clinical diagnostic tests, Epidemiology, Metabolic disorders Heart failure and cardiomyopathies Source Type: research

Perioperative outcomes of patients with hypertrophic cardiomyopathy undergoing non-cardiac surgery
Conclusions Patients with HCM undergoing high-risk and intermediate-risk non-cardiac surgeries have a low perioperative event rate, at an experienced centre. However, they have a higher risk of composite events versus matched patients without HCM.
Source: Heart - September 26, 2016 Category: Cardiology Authors: Dhillon, A., Khanna, A., Randhawa, M. S., Cywinski, J., Saager, L., Thamilarasan, M., Lever, H. M., Desai, M. Y. Tags: Hypertrophic cardiomyopathy, Drugs: cardiovascular system, Heart failure, Acute coronary syndromes, Clinical diagnostic tests, Epidemiology Heart failure and cardiomyopathies Source Type: research

Catheter ablation for atrial fibrillation in hypertrophic cardiomyopathy: a systematic review and meta-analysis
Conclusions The observed complication rate of catheter ablation of AF in patients with HCM was low. Even though the risk of relapse is twofold higher, catheter ablation can be effective in patients with HCM and AF, particularly in patients with paroxysmal AF and smaller atria.
Source: Heart - September 12, 2016 Category: Cardiology Authors: Providencia, R., Elliott, P., Patel, K., McCready, J., Babu, G., Srinivasan, N., Bronis, K., Papageorgiou, N., Chow, A., Rowland, E., Lowe, M., Segal, O. R., Lambiase, P. D. Tags: Tachyarrhythmias, Editor's choice, Hypertrophic cardiomyopathy, Drugs: cardiovascular system, Clinical diagnostic tests Heart failure and cardiomyopathy Source Type: research

Significance of apical cavity obliteration in apical hypertrophic cardiomyopathy
Conclusions The ratio of obliteration to cavity could provide useful information to predict the occurrence of adverse events in apical HCM.
Source: Heart - July 10, 2016 Category: Cardiology Authors: Kim, H., Park, J.-H., Won, K.-B., Yoon, H.-J., Park, H.-S., Cho, Y.-K., Nam, C.-W., Han, S., Hur, S.-H., Kim, Y.-N., Kim, K.-B. Tags: Hypertrophic cardiomyopathy, Drugs: cardiovascular system, Hypertension, Epidemiology Heart failure and cardiomyopathies Source Type: research

Global longitudinal strain is associated with heart failure outcomes in hypertrophic cardiomyopathy
Conclusions In patients with HCM, reduced GLS is an independent factor associated with poor cardiac outcomes, and particularly HF outcomes.
Source: Heart - April 24, 2016 Category: Cardiology Authors: Reant, P., Mirabel, M., Lloyd, G., Peyrou, J., Lopez Ayala, J.-M., Dickie, S., Bulluck, H., Captur, G., Rosmini, S., Guttmann, O., Demetrescu, C., Pantazis, A., Tome-Esteban, M., Moon, J. C., Lafitte, S., McKenna, W. J. Tags: Hypertrophic cardiomyopathy, Drugs: cardiovascular system, Echocardiography, Clinical diagnostic tests Heart failure and cardiomyopathies Source Type: research

Cochrane corner: vitamin K for improved anticoagulation control in patients receiving warfarin
There has been a substantial increase in the use of oral anticoagulants, notably in the ageing population. This is primarily driven by the use of warfarin in people with atrial fibrillation (AF) in order to reduce the risks of thromboembolic events such as stroke.1 In elderly patients with AF, warfarin use has been shown to reduce the relative risk of stroke by >50% compared with aspirin alone.2 Warfarin is also used to treat patients with deep vein thrombosis, mechanical heart valve replacement, cardioversion, cardiomyopathy and antiphospholipid syndrome.1 The clinical benefits of warfarin must also be balanced with po...
Source: Heart - October 11, 2015 Category: Cardiology Authors: Mahtani, K. R., Nunan, D., Heneghan, C. Tags: Drugs: cardiovascular system, Cochrane Corner, Venous thromboembolism, Epidemiology Editorials Source Type: research

Heartbeat: Highlights from the issue
This issue of Heart has a group of articles about hypertrophic cardiomyopathy with two of these studies addressing exercise capacity. In a study from The Heart Hospital in London (See page 644 and figure 1) cardiopulmonary exercise testing showed a reduced peak oxygen consumption and cardiac index in 70 patients with hypertrophic cardiomyopathy compared to normal volunteers. Left ventricular outflow tract obstruction was present in 31% of patients at rest and an additional 14% had obstruction provoked by exercise. Compared to patients without obstruction, outflow obstruction at all levels of exercise was associated with an...
Source: Heart - March 21, 2014 Category: Cardiology Authors: Otto, C. M. Tags: Hypertrophic cardiomyopathy, Drugs: cardiovascular system, Echocardiography, Interventional cardiology, Clinical diagnostic tests Heartbeat Source Type: research

Cardiac output response and peripheral oxygen extraction during exercise among symptomatic hypertrophic cardiomyopathy patients with and without left ventricular outflow tract obstruction
Conclusions Cardiac reserve is reduced in HCM because of failure of SV augmentation. LVOTO exacerbates this abnormal response, but haemodynamic responses vary significantly. Non-invasive exercise haemodynamic assessment may improve understanding of symptoms and help tailor therapy.
Source: Heart - March 21, 2014 Category: Cardiology Authors: Critoph, C. H., Patel, V., Mist, B., Elliott, P. M. Tags: Hypertrophic cardiomyopathy, Drugs: cardiovascular system, Hypertension Heart failure and cardiomyopathies Source Type: research

Cardiac MRI assessment of atrial fibrosis in atrial fibrillation: implications for diagnosis and therapy
Atrial fibrillation (AF) is the most commonly encountered cardiac arrhythmia in clinical practice, with a prevalence of 0.4–1% in the US population.w1 AF is a potent risk factor, increasing the risk of stroke fivefold and accounting for approximately 15% of all strokes in the USA.w2 AF also significantly increases the risk of mortality from heart failure.w3–7 Many therapies, including pharmacological approaches and direct current cardioversion, have been tried to treat this malignant arrhythmia, but were not found to be that effective.1 w8–w11 Catheter ablation of AF has provided better outcomes compared ...
Source: Heart - March 5, 2014 Category: Cardiology Authors: Higuchi, K., Akkaya, M., Akoum, N., Marrouche, N. F. Tags: Tachyarrhythmias, Atrial fibrillation, Education in Heart, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, Drugs: cardiovascular system, Echocardiography, Heart failure, Acute coronary syndromes, Clinical diagnostic tests, Epidemiology Source Type: research

Atrial fibrillation and thromboembolism in patients with hypertrophic cardiomyopathy: systematic review
Conclusions AF is common in HCM and associated with high thromboembolic risk. LA dimension and age are independently associated with AF but the literature is insufficient to create robust clinical tools to predict AF or thromboembolism. Most data suggest that AF patients should be anticoagulated.
Source: Heart - February 19, 2014 Category: Cardiology Authors: Guttmann, O. P., Rahman, M. S., O'Mahony, C., Anastasakis, A., Elliott, P. M. Tags: Hypertrophic cardiomyopathy, Drugs: cardiovascular system, Epidemiology Heart failure and cardiomyopathies Source Type: research

Pages: 1  2