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Clinical impact of direct stenting and interaction with thrombus aspiration in patients with ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention: Thrombectomy Trialists Collaboration
ConclusionDirect stenting rates were higher in patients randomized to thrombus aspiration. Clinical outcomes and myocardial reperfusion measures did not differ significantly between DS and conventional stenting and there was no interaction with thrombus aspiration.
Source: European Heart Journal - April 21, 2018 Category: Cardiology Source Type: research

Long working hours as a risk factor for atrial fibrillation: a multi-cohort study
ConclusionIndividuals who worked long hours were more likely to develop atrial fibrillation than those working standard hours.
Source: European Heart Journal - July 13, 2017 Category: Cardiology Source Type: research

Bradycardia and atrial fibrillation in patients with stable coronary artery disease treated with ivabradine: an analysis from the SIGNIFY study
Conclusion Both in the overall population as well as in the angina subset, bradycardia was common in ivabradine-treated patients, but did not appear to impact outcomes. Emergent AF was relatively rare and did not appear to have an impact on outcomes relative to placebo. Clinical trials registration ISRCTN61576291
Source: European Heart Journal - December 7, 2015 Category: Cardiology Authors: Fox, K., Ford, I., Steg, P. G., Tardif, J.-C., Tendera, M., Ferrari, R., the SIGNIFY investigators Tags: Coronary artery disease Source Type: research

Prognostic impact of supraventricular premature complexes in community-based health checkups: The Ibaraki Prefectural Health Study
Conclusion The presence of SVPCs in 12-lead electrocardiograms was a strong predictor of AF development, and associated with increased risk of CVD in general population.
Source: European Heart Journal - January 17, 2015 Category: Cardiology Authors: Murakoshi, N., Xu, D., Sairenchi, T., Igarashi, M., Irie, F., Tomizawa, T., Tada, H., Sekiguchi, Y., Yamagishi, K., Iso, H., Yamaguchi, I., Ota, H., Aonuma, K. Tags: Arrhythmia/electrophysiology Source Type: research

Clinical implications of new-onset left bundle branch block after transcatheter aortic valve replacement: analysis of the PARTNER experience
Conclusion Persistent, new-onset LBBB occurred in 10.5% of patients without intraventricular baseline conduction who underwent TAVR in the PARTNER experience. New LBBB was not associated with death, repeat hospitalization, stroke, or myocardial infarction at 1 year, but was associated with a higher rate of PPI and failure of left ventricular ejection fraction to improve.
Source: European Heart Journal - June 21, 2014 Category: Cardiology Authors: Nazif, T. M., Williams, M. R., Hahn, R. T., Kapadia, S., Babaliaros, V., Rodes-Cabau, J., Szeto, W. Y., Jilaihawi, H., Fearon, W. F., Dvir, D., Dewey, T. M., Makkar, R. R., Xu, K., Dizon, J. M., Smith, C. R., Leon, M. B., Kodali, S. K. Tags: TAVI Source Type: research

The Atrial Fibrillation Ablation Pilot Study: an European Survey on Methodology and results of catheter ablation for atrial fibrillation conducted by the European Heart Rhythm Association
Conclusion The AFib Ablation Pilot Study provided crucial information on the epidemiology, management, and outcomes of catheter ablation of AFib in a real-world setting. The methods used to assess the success of the procedure appeared at least suboptimal. Even in this context, the 12-month success rate appears to be somewhat lower to the one reported clinical trials.
Source: European Heart Journal - June 7, 2014 Category: Cardiology Authors: Arbelo, E., Brugada, J., Hindricks, G., Maggioni, A. P., Tavazzi, L., Vardas, P., Laroche, C., Anselme, F., Inama, G., Jais, P., Kalarus, Z., Kautzner, J., Lewalter, T., Mairesse, G. H., Perez-Villacastin, J., Riahi, S., Taborsky, M., Theodorakis, G., Tri Tags: Arrhythmia/electrophysiology Source Type: research

Prognostic significance of prolonged PR interval in the general population
Conclusion In the middle-aged general population, prolonged PR interval normalizes in a substantial proportion of subjects during the time course, and it is not associated with an increased risk of all-cause or cardiovascular mortality.
Source: European Heart Journal - January 7, 2014 Category: Cardiology Authors: Aro, A. L., Anttonen, O., Kerola, T., Junttila, M. J., Tikkanen, J. T., Rissanen, H. A., Reunanen, A., Huikuri, H. V. Tags: Arrhythmia/electrophysiology Source Type: research

A new look at atrial fibrillation: lessons learned from drugs, pacing, and ablation therapies
Atrial fibrillation (AF) is the most common arrhythmia and among the leading causes of stroke and heart failure in Western populations. Despite the increasing size of clinical trials assessing the efficacy and safety of AF therapies, achieved outcomes have not always matched expectations. Considering that AF is a symptom of many possible underlying diseases, clinical research for this arrhythmia should take into account their respective pathophysiology. Accordingly, the definition of the study populations to be included should rely on the established as well as on the new classifications of AF and take advantage from a dif...
Source: European Heart Journal - September 14, 2013 Category: Cardiology Authors: Kappenberger, L. Tags: REVIEWS Source Type: research