Bradycardia and atrial fibrillation in patients with stable coronary artery disease treated with ivabradine: an analysis from the SIGNIFY study

Conclusion
Both in the overall population as well as in the angina subset, bradycardia was common in ivabradine-treated patients, but did not appear to impact outcomes. Emergent AF was relatively rare and did not appear to have an impact on outcomes relative to placebo.

Clinical trials registration
ISRCTN61576291

Source: European Heart Journal - December 7, 2015 Category: Cardiology Authors: Fox, K., Ford, I., Steg, P. G., Tardif, J.-C., Tendera, M., Ferrari, R., the SIGNIFY investigators Tags: Coronary artery disease Source Type: research