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Management: National Institute for Health Research (NIHR)

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Total 14 results found since Jan 2013.

Risk of aspirin-related bleeding is higher in the over-75s
Conclusion This valuable cohort study helps to quantify the extent of bleeding risk in people taking aspirin for secondary prevention of cardiovascular disease. Aspirin is well known to carry bleeding risk – particularly in older adults – but this study suggests the risk may be higher than previously thought. The researchers say that for adults under the age of 75, the annual bleeding risk at around 1% is similar to that suggested by previous trials, as is the ratio of bleeds to the number of cardiovascular events. However, this risk increases for older adults, especially for major bleeds of the stomach and upper diges...
Source: NHS News Feed - June 14, 2017 Category: Consumer Health News Tags: Medication Older people Source Type: news

Moderate drinking may reduce heart disease risk
Conclusion This study paints a more complicated picture than the "Pint a day keeps the doctor away" story proffered by The Sun. It seems to confirm the findings of other studies, which have shown that non-drinkers tend to have a higher risk of cardiovascular diseases than people who drink moderately. It suggests that some cardiovascular diseases (mainly those directly affecting the heart) seem to have a stronger link to a possible protective effect from alcohol than other vascular diseases, such as mini-strokes and bleeding in the brain. However, this can't be concluded with certainty due to the study design. We ...
Source: NHS News Feed - March 23, 2017 Category: Consumer Health News Tags: Heart/lungs Food/diet Lifestyle/exercise Source Type: news

Weekend-only workouts 'still give an important health boost'
Conclusion This survey aimed to investigate patterns of physical activity in adults over the age of 40 and the potential impact on their cause of death. The study found that, compared with those who were not physically active, all active groups saw a reduction in their risk of death from any cause and cardiovascular disease. Being active at the weekend only had no effect on cancer mortality. However, interpretations around the optimal level of activity are difficult when you note that insufficient activity gave similar mortality reductions as the recommended regular activity. This study has both strengths and limitations...
Source: NHS News Feed - January 10, 2017 Category: Consumer Health News Tags: Lifestyle/exercise Heart/lungs Cancer Source Type: news

Handful of nuts 'cuts heart disease and cancer' risk
Conclusions This systematic review finds evidence that nut intake may be linked with reduced risk of cardiovascular disease, cancer and death. The systematic review has several strengths. It identified a large number of studies with a large total sample size. It also included only prospective cohorts assessing nut consumption and then followed up later disease outcomes. It excluded cross sectional studies, which assess diet and disease at the same time, and so can't show the direction of effect. It also excluded cohorts that have retrospectively questioned diet when the person already has the disease, which could be subjec...
Source: NHS News Feed - December 5, 2016 Category: Consumer Health News Tags: Food/diet Cancer Heart/lungs Source Type: news

Exercise benefits you - even in polluted city air
Conclusion This modelling study aimed to assess exposure to air pollution through physical activity and the associated health risks around the world. The study found the background pollution level required to reach the tipping point is only present in less than 1% of cities, according to the WHO. In an average city physical exercise will remain beneficial up to seven hours a day for cycling or 16 hours for walking. In highly polluted areas this became as low as 30 minutes a day for cycling and 90 minutes of walking. The main limitation of this study is that it is only a model and we do not know how true to life the findi...
Source: NHS News Feed - May 6, 2016 Category: Consumer Health News Tags: Heart/lungs Lifestyle/exercise Source Type: news

Heart attack, stroke and diabetes 'can shorten life by 23 years'
Conclusion This study used two large cohort-derived data sets to estimate the number of years of life lost as the result of a history of heart attack, stroke or diabetes across different ages. The study's large size, relevance to the UK and long-term follow-up increases our confidence in its conclusions and their relevance to England and Wales. As with all studies, it has limitations, but these were relatively small and unlikely to affect the main conclusions. This study shows a history of stroke, type 2 diabetes and heart attack can significantly shorten life expectancy, especially if these conditions are developed earli...
Source: NHS News Feed - July 8, 2015 Category: Consumer Health News Tags: Heart/lungs Diabetes Lifestyle/exercise Neurology Older people Source Type: news

GP receptionists 'could help prevent stroke deaths'
Conclusion This valuable and well-designed study assessed a cross-section of general practices from one UK region, looking at how well receptionists are able to recognise the signs of stroke and give appropriate advice – either immediately passing patients on to the GP or telling them to contact emergency services. The study has many strengths. These include the large sample of GP surgeries and calls assessed, and that receptionists weren't aware of the nature of the study and the calls were unannounced. At the end of each individual call receptionists were told the call was part of the study and no further action was n...
Source: NHS News Feed - June 29, 2015 Category: Consumer Health News Tags: Medical practice Neurology Source Type: news

Overweight diabetics 'live longer' than slimmer diabetics
Conclusion This large prospective cohort following over 10,000 older adults with type 2 diabetes for 10 years has found that while being overweight or obese is linked to increased risk of cardiovascular events, being overweight is linked to reduced risk of death. This is similar to the "obesity paradox" seen in some other studies, where being overweight or obese is associated with a survival benefit in people with established cardiovascular disease. The researchers note that 16 other studies have assessed the same question and found conflicting results. Their study aimed to improve on the methods in these studies...
Source: NHS News Feed - May 11, 2015 Category: Consumer Health News Tags: Diabetes Food/diet Obesity Source Type: news

Following UK dietary advice may cut heart disease risk
Conclusion This study showed that following dietary recommendations closely for 12 weeks can reduce blood pressure by a significant amount, which is likely to cut the chances of having a heart attack or stroke for an average healthy middle-aged person. The diet also affects cholesterol levels, but the overall effect of this may be modest. The study appears to have been carefully conducted to avoid biasing the results. The researchers gave butter or margarine spread and cooking oil to people in both groups, for example, and asked everyone to fill out food diaries, as well as taking urine samples for nutrient analysis. Thi...
Source: NHS News Feed - March 19, 2015 Category: Consumer Health News Tags: Food/diet Heart/lungs Source Type: news

Lack of vitamin D may 'raise dementia risk'
Conclusion This cohort study of more than 1,650 elderly people has found that over 5.6 years, severe vitamin D deficiency is associated with approximately twice the risk of developing dementia or Alzheimer's disease. It also found moderate deficiency is associated with a 50% increase in risk compared with healthy levels of vitamin D. With this being a cohort study, it was not able to show that low levels of vitamin D caused dementia or Alzheimer's disease – it was simply able to show an association. Other factors that can increase the risk of developing dementia, such as a poor diet, lack of activity and general poor h...
Source: NHS News Feed - August 7, 2014 Category: Consumer Health News Tags: Lifestyle/exercise Older people Neurology Mental health Source Type: news

Statins side effects are minimal, study argues
ConclusionThis meta-analysis pooled results from 29 studies and has shown a very small increased risk of newly diagnosed diabetes mellitus. This is the same as the decreased risk of any cause of death in people taking statins, compared to placebo, to prevent a heart attack or stroke.The researchers point out some limitations to the meta-analysis: Each study did not report on all of the side effects, meaning that for each category of side effect, the number of participants differed. The side effect categories were only included if at least 500 people had reported suffering from it. This means there may be numerous other si...
Source: NHS News Feed - March 13, 2014 Category: Consumer Health News Tags: Heart/lungs Medication Source Type: news

Flu jab "may cut" stroke risk by a quarter
ConclusionThis research finds that, overall, having the flu vaccine reduced the risk of a person experiencing a stroke by about 25%. The reduction in risk seemed to be greatest within the first three months of vaccination, but remained for up to 12 months.  However, the effect lasted only if the vaccine was given early in the flu season (September to mid-November); giving the vaccine late in the flu season (mid-November to February) was not associated with significantly reduced risk.The research benefits from using data coded within the General Practice Research Database for England and Wales for almost 50,000 people with...
Source: NHS News Feed - February 21, 2014 Category: Consumer Health News Tags: Heart/lungs Neurology Older people Source Type: news

Walking reduces heart disease in people at risk
Conclusion This study of adults at high risk of type 2 diabetes and heart disease has found that every 2,000 steps they normally took each day was associated with a 10% lower risk of a cardiovascular event. And 12 months later, each extra 2,000 steps per day people did beyond their original number of steps was associated with an additional 8% difference in the cardiovascular event rate. This large study recruited participants from around the world and the researchers adjusted for a number of potential confounders. However, the study had a number of limitations, including: A large amount of information on the number of s...
Source: NHS News Feed - December 23, 2013 Category: Consumer Health News Tags: Lifestyle/exercise Source Type: news

Dementia rates dropping
Conclusion This study suggests that the prevalence of dementia in over 65s in 2011 is lower than would have been expected.  The study had many strengths, including the large number of people it interviewed from different areas and the consistent research methods adopted in 1991 and again in 2011, particularly using the same criteria to diagnose dementia at both time points. This means we can be relatively sure that its conclusions are reliable. That said, it does have some limitations to consider. The response rate in 2011 (56%) was much lower than in 1991 (80%). The study authors offer a number of explanations for this...
Source: NHS News Feed - July 17, 2013 Category: Consumer Health News Tags: Neurology Older people Medical practice Source Type: news