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Source: JAMA Neurology
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Total 364 results found since Jan 2013.
Association of Atrial Septal Aneurysm and Shunt Size With Stroke Recurrence
This individual patient data meta-analysis evaluates the association of patent foramen ovale closure on stroke recurrence according to shunt size and/or the presence of an atrial septal aneurysm.
Source: JAMA Neurology - October 10, 2022 Category: Neurology Source Type: research
Association of Vascular Risk Factors and Genetic Factors With Penetrance of Variants Causing Monogenic Stroke
This cohort study examines data from UK Biobank participants who had whole-exome sequencing to determine the frequency of pathogenic variants in the 3 most common monogenic cerebral small vessel diseases and their associations with prevalent and incident stroke and dementia.
Source: JAMA Neurology - October 27, 2022 Category: Neurology Source Type: research
Optimal Intensity and Duration of Walking Rehabilitation in Patients With Chronic Stroke
This randomized clinical trial compares vigorous vs moderate walking exercise to assess the optimal intensity and training duration to maximize improvement in walking capacity among stroke survivors with walking limitations.
Source: JAMA Neurology - February 23, 2023 Category: Neurology Source Type: research
Transcarotid Artery Revascularization for Stroke Prevention —Multiple Elephants in the Room
In the saga of carotid revascularization procedures, carotid endarterectomy (CEA) has a track record of longer than 65 years. CEA has been shown in clinical trials to be useful for stroke prevention in select patients with symptomatic internal carotid artery stenosis and to a lesser extent, asymptomatic stenosis.
Source: JAMA Neurology - March 20, 2023 Category: Neurology Source Type: research
Outcomes After Endovascular Therapy With Procedural Sedation vs General Anesthesia in Acute Ischemic Stroke
This randomized clinical trial evaluates whether general anesthesia or procedural sedation for anterior circulation large-vessel occlusion acute ischemic stroke thrombectomy are associated with a difference in periprocedural complications and 3-month functional outcome.
Source: JAMA Neurology - April 3, 2023 Category: Neurology Source Type: research
Association of Mortality and Risk of Epilepsy With Type of Acute Symptomatic Seizure After Ischemic Stroke
This cohort study examines data for patients with acute ischemic stroke to compare the risk of poststroke mortality and epilepsy between different types of acute symptomatic seizures.
Source: JAMA Neurology - April 10, 2023 Category: Neurology Source Type: research
Trends in the Prevalence of Stroke Among Community-Dwelling Individuals in the US, 1999-2018
This cross-sectional study estimates trends in stroke prevalence representative of the noninstitutionalized civilian population of US adults 20 years and older using data from the 1999 to 2018 National Health and Nutrition Examination Surveys.
Source: JAMA Neurology - April 24, 2023 Category: Neurology Source Type: research
Dual Thrombolytic Therapy With Mutant Prourokinase and Small Bolus Alteplase for Ischemic Stroke
This randomized clinical trial of individuals with ischemic stroke assesses the safety and efficacy of treatment with a dual plasminogen activator vs usual treatment with intravenous alteplase.
Source: JAMA Neurology - May 22, 2023 Category: Neurology Source Type: research
Symptomatic Intracranial Hemorrhage With Tenecteplase vs Alteplase in Patients With Acute Ischemic Stroke
This cohort study evaluates rates of symptomatic intracranial hemorrhage following stroke with tenecteplase vs alteplase.
Source: JAMA Neurology - May 30, 2023 Category: Neurology Source Type: research
Safety and Efficacy of ApTOLL in Patients With Ischemic Stroke Undergoing Endovascular Treatment
This randomized clinical trial investigates the safety and efficacy of ApTOLL as a neuroprotectant drug for patients with ischemic stroke when given in combination with endovascular treatment.
Source: JAMA Neurology - June 20, 2023 Category: Neurology Source Type: research
Efficacy and Safety of Butylphthalide in Patients With Acute Ischemic Stroke
This randomized clinical trial assesses the efficacy and safety of DL-3-n-butylphthalide in patients with acute ischemic stroke receiving reperfusion therapy of intravenous thrombolysis and/or endovascular treatment.
Source: JAMA Neurology - June 26, 2023 Category: Neurology Source Type: research
Safety and Efficacy of Tenecteplase vs Alteplase in Patients With Large Vessel Occlusion Stroke
This prespecified secondary analysis of the ACT randomized clinical trial evaluates the safety and efficacy of tenecteplase compared to alteplase among patients with large vessel occlusion stroke.
Source: JAMA Neurology - July 10, 2023 Category: Neurology Source Type: research
E-Cigarettes and Stroke Risk —Present Uncertainties and Future Directions
This Viewpoint describes the need for epidemiological studies of the association between e-cigarette use and risk of stroke to inform decision-making among patients, health care practitioners, and policy makers.
Source: JAMA Neurology - July 10, 2023 Category: Neurology Source Type: research
Association Between Thrombectomy and Functional Outcomes in Pediatric Patients With Acute Ischemic Stroke From LVO
This case-control study evaluates whether pediatric patients with acute large vessel occlusion (LVO) stroke who undergo thrombectomy have better clinical outcomes than matched patients managed conservatively.
Source: JAMA Neurology - July 24, 2023 Category: Neurology Source Type: research
Development and Validation of a Postprocedural Model to Predict Outcome After Endovascular Treatment for Ischemic Stroke
This prognostic study investigates the effectiveness of a prognostic tool to predict the functional outcome of individual patients after endovascular treatment for ischemic stroke.
Source: JAMA Neurology - July 31, 2023 Category: Neurology Source Type: research
