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Source: JAMA Neurology
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Total 364 results found since Jan 2013.
Questions on Predicting Early Neurological Deterioration in Patients With Minor Stroke and Large-Vessel Occlusion —Reply
In Reply We thank Ospel and colleagues for their thoughtful comments on our article showing that more proximal occlusion and greater thrombus length predict early neurological deterioration of ischemic origin (ENDi) in patients with acute minor ischemic stroke with large-vessel occlusion treated with intravenous thrombolysis, with implications regarding how to best manage these patients. Although the precise pathophysiological links between more proximal occlusion, a longer thrombus, and ENDi are uncertain, we fully agree that a leading hypothesis is in situ thrombus extension leading to secondary hemodynamic compromise vi...
Source: JAMA Neurology - July 6, 2021 Category: Neurology Source Type: research
Multiple Facial Ulcers Following a Stroke
A 66-year-old man presents with multiple progressive ulcers and hypesthesia on the right side of his face, new-onset hemiplegia and hemianopsia on the left side of his face, and ischemic posterior circulation stroke. What is your diagnosis?
Source: JAMA Neurology - July 19, 2021 Category: Neurology Source Type: research
Direct to Angiography Suite Without Stopping for Computed Tomography Imaging in Acute Stroke
This randomized clinical trial assesses whether direct transfer to the angiography suite improves clinical outcomes compared with usual imaging workflow among patients within 6 hours from onset of symptoms for large vessel occlusion ischemic stroke.
Source: JAMA Neurology - August 2, 2021 Category: Neurology Source Type: research
Depression Outcomes Among Patients Treated With Fluoxetine for Stroke Recovery
This randomized clinical trial investigates whether daily treatment with 20 mg of fluoxetine hydrochloride reduces the proportion of people affected by symptoms of depression after stroke.
Source: JAMA Neurology - August 2, 2021 Category: Neurology Source Type: research
Effects of Antiplatelet Therapy After Stroke Caused by Intracerebral Hemorrhage
A follow-up of the Restart or Stop Antithrombotics Randomized Trial, this study further examines the long-term effects of antiplatelet therapy after stroke caused by intracerebral hemorrhage.
Source: JAMA Neurology - September 3, 2021 Category: Neurology Source Type: research
Noncontrast CT vs CT Perfusion or MRI Selection in Late Presentation of Large-Vessel –Occlusion Stroke
This cohort study compares the clinical outcomes of patients with stroke who presented 6 to 24 hours after symptom onset and were selected for mechanical thrombectomy by noncontrast computed tomography vs those selected by computed tomography perfusion or magnetic resonance imaging.
Source: JAMA Neurology - November 8, 2021 Category: Neurology Source Type: research
Comparison of Ticagrelor vs Clopidogrel With Aspirin in Minor Ischemic Stroke and Transient Ischemic Attack
This network meta-analysis compares ticagrelor and aspirin with clopidogrel and aspirin in patients with acute minor ischemic stroke or transient ischemic attack in the prevention of recurrent strokes or death.
Source: JAMA Neurology - December 6, 2021 Category: Neurology Source Type: research
Disentangling Workflow Paradigms and Treatment Decision-Making in Acute Ischemic Stroke —Reply
In Reply We thank Ospel and Goyal for their interest in the Evaluation of Direct Transfer to Angiography Suite vs Computed Tomography Suite in Endovascular Treatment (ANGIOCAT) study and read with interest their letter in which they express some concerns in relation to the direct-to-angiography suite (DTAS) paradigm. In the ANGIOCAT study, patients adjudicated to the conventional imaging group, despite receiving computed tomography perfusion (CTP) in some cases, achieved one of the shortest workflow times reported ever (door-to-puncture time of 44 minutes). According to guidelines, CTP was never used to exclude patients fr...
Source: JAMA Neurology - February 7, 2022 Category: Neurology Source Type: research
Data Do Not Support Selection of Patients for Stroke Treatment Within the 16- to 24-Hour Interval
To the Editor The Diffusion-Weighted Imaging or Computerized Tomography Perfusion Assessment With Clinical Mismatch in the Triage of Wake-Up and Late Presenting Strokes Undergoing Neurointervention With Trevo (DAWN) trial demonstrated benefit of endovascular treatment (EVT) in select patients 6 to 24 hours after last known well (LKW) with clinical imaging mismatch. The Endovascular Therapy Following Imaging Evaluation for Ischemic Stroke 3 (DEFUSE 3) trial demonstrated benefit of EVT in select patients 6 to 16 hours after LKW with target perfusion-imaging mismatch. In the article by Albers et al, the authors present indepe...
Source: JAMA Neurology - February 14, 2022 Category: Neurology Source Type: research
Intensity of LDL Cholesterol Lowering and Secondary Stroke Prevention
This meta-analysis of randomized clinical trials evaluates the association of more intensive vs less intensive low-density lipoprotein cholesterol –lowering statin-based therapies with outcomes for patients with ischemic stroke.
Source: JAMA Neurology - February 21, 2022 Category: Neurology Source Type: research
Effect of Gamification With Social Incentives on Daily Steps After Stroke
This randomized clinical trial assesses whether gamification with social incentives increases daily steps among adults with stroke.
Source: JAMA Neurology - March 28, 2022 Category: Neurology Source Type: research
Incidence and Natural History of Pediatric Large Vessel Occlusion Stroke
This cohort study investigates the incidence and natural history of pediatric large vessel occlusion stroke.
Source: JAMA Neurology - March 28, 2022 Category: Neurology Source Type: research
Implications of the National Institutes of Health Stroke Scale Cookie Theft Picture —A Closer Look
This Viewpoint discusses the implications of use of the National Institutes of Health Stroke Scale Cookie Theft picture.
Source: JAMA Neurology - June 13, 2022 Category: Neurology Source Type: research
Prevalence of Atherosclerotic Risk Factors Among Children and Young Adults With Arterial Ischemic Stroke
This case-control study assesses hypertension, hyperlipidemia, obesity, smoking, and diabetes as risk factors associated with incident arterial ischemic stroke in children and young adults, stratified by decade of age.
Source: JAMA Neurology - August 1, 2022 Category: Neurology Source Type: research
Diverging Temporal Trends in Stroke Incidence in Younger vs Older People
This systematic review and meta-analysis compares temporal trends in incidence of stroke at younger vs older ages in high-income countries.
Source: JAMA Neurology - August 9, 2022 Category: Neurology Source Type: research
