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Source: JAMA Neurology

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Total 364 results found since Jan 2013.

Targeting Pioglitazone Therapy After Stroke or Transient Ischemic Attack
This secondary analysis of the Insulin Resistance Intervention After Stroke trial estimates the relative and absolute effectiveness of pioglitazone after ischemic stroke or transient ischemic attack in subgroups of patients defined by pretreatment risk for stroke or myocardial infarction.
Source: JAMA Neurology - September 18, 2017 Category: Neurology Source Type: research

Stroke Quality of Care in GWTG-Stroke Hospitals
This longitudinal cohort study compares quality of stroke care measures for patients admitted to hospitals participating and not participating in Get With The Guidelines –Stroke.
Source: JAMA Neurology - August 6, 2018 Category: Neurology Source Type: research

Remote Ischemic Perconditioning for the Treatment of Acute Ischemic Stroke —Reply
In Reply We thank Zhao et al for the interest in our randomized clinical trial. We agree that it is of interest to evaluate remote ischemic perconditioning specifically in patients with acute ischemic stroke and mismatch. We did not target these patients exclusively, because when the Remote Ischemic Conditioning in Acute Brain Infarction (RESCUE BRAIN) was designed in 2012, there was no proof of the efficacy of this approach; the DWI or CTP Assessment with Clinical Mismatch in the Triage of Wake-Up and Late Presenting Strokes Undergoing Neurointervention with Trevo (DAWN) and Endovascular Therapy Following Imaging Evaluati...
Source: JAMA Neurology - September 28, 2020 Category: Neurology Source Type: research

Self-driven Prehospital Triage Decisions for Suspected Stroke
Setting the course for prehospital triage of patients with suspected stroke is challenging. Few would disagree, and to be frank, this is rather old news. Yet the critical question remains unsolved: how do we optimally drive prehospital triage decisions for patients with suspected stroke? Central to this question is the challenge of identifying stroke specifically due to large vessel occlusion (LVO) in the prehospital setting. Furthermore, the “best choice” among the various prehospital LVO screening tools available has not been clear. Although several versions have been developed, many had not been validated in the pre...
Source: JAMA Neurology - November 30, 2020 Category: Neurology Source Type: research

Risk of Hemorrhagic Stroke in Patients With Coronavirus Disease 2019
To the Editor We read with interest the article by Merkler et al regarding the increased incidence of ischemic stroke in patients with coronavirus disease 2019 (COVID-19) compared with those with influenza. The authors also reported that 13% of patients with COVID-19 were receiving anticoagulation at the time of the stroke. Could the authors comment on the rate of anticoagulant use in patients with COVID-19 who did not have an ischemic stroke? This would also be helpful to assess the possibility that anticoagulation may have been protective.
Source: JAMA Neurology - March 8, 2021 Category: Neurology Source Type: research

Mobile Stroke Unit or Usual Care for Acute Ischemic Stroke Management
This systematic review and meta-analysis investigates whether mobile stroke unit use is associated with better functional outcomes in patients with acute ischemic stroke.
Source: JAMA Neurology - February 7, 2022 Category: Neurology Source Type: research

Stroke Severity in Atrial Fibrillation Screening
This post hoc analysis of the Atrial Fibrillation Detected by Continuous Electrocardiogram Monitoring Using Implantable Loop Recorder to Prevent Stroke in High-Risk Individuals (LOOP) randomized clinical trial investigates if implantable loop recorder screening for atrial fibrillation can reduce the risk of severe stroke in individuals with risk factors or prior stroke history.
Source: JAMA Neurology - August 29, 2022 Category: Neurology Source Type: research

Predictors of Atrial Fibrillation in Patients With Stroke Attributed to Large- or Small-Vessel Disease
This prespecified analysis of the Stroke of Known Cause and Underlying Atrial Fibrillation (STROKE AF) randomized clinical trial investigates the association of commonly assessed risk factors with undiagnosed atrial fibrillation in patients with ischemic stroke from large- or small-vessel disease.
Source: JAMA Neurology - November 14, 2022 Category: Neurology Source Type: research

Care and Outcomes of Patients With In-Hospital Stroke
This prospective cohort study examines stroke care delivery and outcomes for patients with in-hospital vs community-onset stroke.
Source: JAMA Neurology - May 4, 2015 Category: Neurology Source Type: research

Endovascular Therapy for Acute Ischemic Stroke
Patients with an occlusion of the distal internal carotid or proximal middle cerebral artery have among the most severe types of ischemic stroke that typically produce life-altering disabilities. Prior to a few months ago, the standard of care for such patients included intravenous (IV) alteplase and comprehensive peristroke care to avoid complications, including measures to prevent another stroke and comprehensive rehabilitation.
Source: JAMA Neurology - August 3, 2015 Category: Neurology Source Type: research

Intravenous Tissue Plasminogen Activator for Acute Ischemic Stroke
This observational study using data from the Get With the Guidelines–Stroke registry investigates the risks and benefits associated with long-term antiplatelet therapy among adult patients with ischemic stroke who receive intravenous tissue plasminogen activator.
Source: JAMA Neurology - November 9, 2015 Category: Neurology Source Type: research

Definition and Implications of the Preventable Stroke
This study tests whether most patients with acute stroke exhibited some degree of stroke preventability.
Source: JAMA Neurology - December 7, 2015 Category: Neurology Source Type: research

Telemedicine in Prehospital Stroke Evaluation and Thrombolysis
This observational study tested whether telemedicine is reliable and remote physician presence adequate for acute stroke treatment using a mobile stroke treatment unit.
Source: JAMA Neurology - December 7, 2015 Category: Neurology Source Type: research

Time to Reperfusion and Treatment Effect for Acute Ischemic Stroke
This randomized clinical trial evaluates the influence of time from stroke onset to the start of treatment and from onset to reperfusion on the effect of intra-arterial treatment in a population of patients with acute ischemic stroke.
Source: JAMA Neurology - December 21, 2015 Category: Neurology Source Type: research

The Challenges of Stroke Prediction Scores
Transient ischemic attack (TIA) and stroke prediction scores have been a topic of both clinical and research interest for decades. The goal of these scores is to identify high-risk patients for both prognostic and clinical management purposes. There are several TIA and stroke prediction scores that aim to prognosticate recurrence or worsening of cerebrovascular events (CVEs). Some are purely clinical scales (eg, California, ABCD, ABCD2, and ABCD3), while others incorporate cerebral parenchyma and/or vascular imaging (eg, Clinical and Imaging-based Predictive model, Recurrence Risk Estimator at 90 Days, ABCDE+, ABCD-I, ABCD...
Source: JAMA Neurology - March 21, 2016 Category: Neurology Source Type: research