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Source: The American Journal of Emergency Medicine

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Total 261 results found since Jan 2013.

How should we treat patients who wake up with a stroke? A review of recent advances in management of acute ischemic stroke
Acute ischemic strokes account for 85% of all strokes and are the fifth leading cause of mortality in the United States. About one in five of all ischemic strokes occur during sleep and are not noticed until the patient wakes up with neurological deficits. There is growing evidence to support that a significantly higher number of stroke patients could benefit from more aggressive care, especially those patients who wake up with strokes. There is increasing research to support a physiologically-based approach based on advanced imaging rather than simply a time-based determination of whether or not a patient would benefit from reperfusion.
Source: The American Journal of Emergency Medicine - February 21, 2019 Category: Emergency Medicine Authors: Danielle Biggs, Michael E. Silverman, Frank Chen, Brian Walsh, Peter Wynne Source Type: research

A new marker identification of high risk stroke patients: Jugular saturation
The aim of this prospective study; to investigate in emergency patients with stroke the relationship between jugular saturation and National Institutes of Health Stroke Scale (NIHSS), lesion volume and mortality score.
Source: The American Journal of Emergency Medicine - March 26, 2019 Category: Emergency Medicine Authors: Mevlut Guven, Nazire Belgin Akilli, Ramazan Koylu, Vefa Oner, Merve Guven, Muhammed Rasit Ozer Source Type: research

Impact of CT scanner location on door to imaging time for emergency department stroke evaluation
Stroke is a potentially serious condition commonly diagnosed in the ED. Time to diagnosis can be crucial to maximizing outcome in a majority of ischemic stroke cases amenable to thrombolytic therapy.
Source: The American Journal of Emergency Medicine - August 13, 2019 Category: Emergency Medicine Authors: William Bonadio Source Type: research

Prehospital Supplemental Oxygen for Acute Stroke – a Retrospective Analysis
This study examines the effects of prehospital sO2 in stroke.
Source: The American Journal of Emergency Medicine - November 17, 2019 Category: Emergency Medicine Authors: Layne Dylla, David H. Adler, Beau Abar, Curtis Benesch, Courtney MC Jones, M. Kerry O'Banion, Jeremy T Cushman Source Type: research

A knack for “NAC”: treatment for heat stroke induced acute liver injury: A case report
We present a case of heat stroke resulting in acute liver injury (ALI) successfully treated with intravenous N-acetylcysteine (NAC).
Source: The American Journal of Emergency Medicine - November 27, 2019 Category: Emergency Medicine Authors: Brian Monzon, Kathleen Hegarty, Megan A. Rech Source Type: research

Thromboelastography for prediction of hemorrhagic transformation in patients with acute ischemic stroke
Thromboelastography (TEG) provides a rapid assessment of the hemostatic processes of a patient in emergency settings. There are limited data on TEG as a predictive tool for hemorrhagic transformation in patients with acute ischemic stroke. We investigated whether TEG values on admission could predict hemorrhagic transformation in patients with acute ischemic stroke.
Source: The American Journal of Emergency Medicine - May 22, 2020 Category: Emergency Medicine Authors: Gina Yu, Youn-Jung Kim, Sang-Beom Jeon, Won Young Kim Source Type: research

A knack for “NAC”: Treatment for heat stroke induced acute liver injury
We present a case of heat stroke resulting in acute liver injury (ALI) successfully treated with intravenous N-acetylcysteine (NAC).
Source: The American Journal of Emergency Medicine - November 27, 2019 Category: Emergency Medicine Authors: Brian Monzon, Kathleen Hegarty, Megan A. Rech Tags: Case Report Source Type: research

Retrospective analysis of the hemodynamic consequences of prehospital supplemental oxygen in acute stroke
This study examines the hemodynamic consequences of prehospital sO2 in stroke.
Source: The American Journal of Emergency Medicine - July 9, 2020 Category: Emergency Medicine Authors: Layne Dylla, Jeremy T. Cushman, Beau Abar, Curtis Benesch, Courtney M.C. Jones, M. Kerry O'Banion, David H. Adler Source Type: research

SARS-CoV-2 infection and its association with thrombosis and ischemic stroke: a review
This review of current literature provides background to the COVID-19 pandemic, as well as an examination of potential pathophysiologic mechanisms behind development of thrombosis and ischemic stroke related to COVID-19. SARS-CoV-2 infection is well-documented to cause severe pneumonia, however, thrombosis and thrombotic complications, such as ischemic stroke, have also been documented in a variety of patient demographics. SARS-CoV-2 infection is known to cause a significant inflammatory response, as well as invasion of vascular endothelial cells, resulting in endothelial dysfunction.
Source: The American Journal of Emergency Medicine - September 28, 2020 Category: Emergency Medicine Authors: Jonathan Snell Source Type: research

Tenecteplase for thrombolysis in stroke patients: Systematic review with meta-analysis
Alteplase is an approved treatment for acute ischemic stroke. Tenecteplase is a genetically modified form of alteplase, with lower cost and a more favourable pharmacokinetic profile allowing bolus injection. The aim of this study was to compare both drugs in adult patients with acute ischemic stroke undergoing thrombolysis.
Source: The American Journal of Emergency Medicine - December 24, 2020 Category: Emergency Medicine Authors: M. Oliveira, M. Fidalgo, L. Font ão, J. Antão, S. Marques, V. Afreixo, T. Gregório Source Type: research

Ischemic stroke presenting as fluctuating focal weakness in an otherwise healthy young man
A 32-year-old man presented to our emergency department (ED) with no complaints after paramedics responded to a fall. Medics noted left-sided weakness on scene. Symptoms were initially absent in the ED, although later recurred, and included dramatically waxing and waning focal weakness. An acute middle cerebral artery ischemic stroke was diagnosed, and tissue plasminogen activator was administered. Despite a fluctuating course of symptoms, our patient ultimately achieved a complete recovery.
Source: The American Journal of Emergency Medicine - March 13, 2013 Category: Emergency Medicine Authors: Melanie J. Lippmann, Adam H. Miller Tags: Case Reports Source Type: research

Rescue thrombolysis in the treatment of cardiac shock and acute stroke
The patients with ST-elevation myocardial infarction are primarily managed with percutaneous coronary intervention (PCI) or thrombolysis. It is well accepted that rescue PCI should be implemented in case of unsuccessful thrombolysis. However, the reverse, rescue thrombolysis, that is, administering of thrombolytic therapy in a patient in whom primary PCI fails, is not well defined. There are no available data about rescue thrombolysis so far. We represent a 43-year-old male patient with Buerger disease (thromboangiitis obliterans) who was admitted to our emergency department for cardiac shock related to inferior and right ...
Source: The American Journal of Emergency Medicine - April 19, 2013 Category: Emergency Medicine Authors: Sukru Akyuz, Mustafa Azmi Sungur, Cevdet Donmez, Aylin Sungur, Nese Cam Tags: Case Reports Source Type: research

The locked-in syndrome: posterior stroke in the ED
We present this report and brief review as it is unusual to watch locked-in syndrome evolve in the ED. Providers should be aware of the presenting symptoms and the differential diagnosis for bulbar muscle weakness as well as the management of posterior stroke.
Source: The American Journal of Emergency Medicine - May 22, 2013 Category: Emergency Medicine Authors: Corey Goldberg, Stephen Topp, Christopher Hopkins Tags: Case Reports Source Type: research

Successful management of heat stroke associated with multiple-organ dysfunction by active intravascular cooling
We report successful cooling with initial intravascular cooling use that rapidly achieved the target temperature with continued normothermia thereafter.
Source: The American Journal of Emergency Medicine - June 12, 2014 Category: Emergency Medicine Authors: Hideyuki Hamaya, Toru Hifumi, Kenya Kawakita, Tomoya Okazaki, Kazutaka Kiridume, Natsuyo Shinohara, Yuko Abe, Koshiro Takano, Masanobu Hagiike, Yasuhiro Kuroda Source Type: research

Re-administration of Intravenous Alteplase in Acute Ischemic Stroke Patients: Case Series and Systematic Review
Background: Due to a high risk of recurrence of ischemic events, some patients may be candidates for re-administration of intravenous (IV) alteplase. Methods: We performed a single center review and performed a search on PubMed from January 1966 to April 2014 for cases of re-administration of alteplase. Favorable outcome was defined by a modified Rankin scale of 0-2 at discharge or at 1-3 months, improvement of ≥4 points within 24 hours in the National Institutes of Health Stroke Scale (NIHSS) score, or as a major improvement in the 72-hour NIHSS score.
Source: The American Journal of Emergency Medicine - July 30, 2014 Category: Emergency Medicine Authors: Adnan I. Qureshi, Ahmed A. Malik, Melissa Freese, Michelle Thompson, Asif A. Khan, M. Fareed K. Suri Source Type: research