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Two older drugs could be 'repurposed' to fight dementia
Conclusion This early stage experimental research has demonstrated a beneficial neurological effect of trazodone and dibenzoylmethane on mice with diseases mimicking neurodegenerative diseases. It is important to acknowledge that this is animal research and therefore the drugs might not have the same effect when they are trialled on humans. That being said, trazodone is already an approved drug for depression and sleep problems and has therefore already passed safety tests. If the mechanisms of neurodegeneration in humans and mice are similar, it is possible trazodone could be used in the future in treating Alzheimer's and...
Source: NHS News Feed - April 20, 2017 Category: Consumer Health News Tags: Older people Neurology Medication Source Type: news

Moderate drinking may reduce heart disease risk
Conclusion This study paints a more complicated picture than the "Pint a day keeps the doctor away" story proffered by The Sun. It seems to confirm the findings of other studies, which have shown that non-drinkers tend to have a higher risk of cardiovascular diseases than people who drink moderately. It suggests that some cardiovascular diseases (mainly those directly affecting the heart) seem to have a stronger link to a possible protective effect from alcohol than other vascular diseases, such as mini-strokes and bleeding in the brain. However, this can't be concluded with certainty due to the study design. We ...
Source: NHS News Feed - March 23, 2017 Category: Consumer Health News Tags: Heart/lungs Food/diet Lifestyle/exercise Source Type: news

A Mediterranean diet in the UK would save 20,000 lives a year as one in eight deaths from heart attack and stroke could be prevented by the change
Researchers from Cambridge University evaluated the effects of an olive oil, fish and nut-rich diet on the health of ordinary people in England - and found it could prevent deaths.
Source: the Mail online | Health - September 29, 2016 Category: Consumer Health News Source Type: news

Our Sedentary Lifestyles Cost About 5 Million Lives A Year
By Kate Kelland LONDON (Reuters) - A study of one million people has found that physical inactivity costs the global economy $67.5 billion a year in healthcare and productivity losses, but an hour a day of exercise could eliminate most of that. Sedentary lifestyles are linked to increased risks of heart disease, diabetes and cancer, researchers found, but activity - such as brisk walking - could counter the higher likelihood of early death linked with sitting for eight or more hours a day. Such inactivity is estimated to cause more than 5 million deaths a year - almost as many as smoking, which the World Health Organi...
Source: Healthy Living - The Huffington Post - July 28, 2016 Category: Consumer Health News Source Type: news

Lessons Learned From Trends in Insufficient Sleep Across the United States
This article originally appeared on the Amerisleep blog. Rosie Osmun is the Creative Content Manager at Amerisleep, a progressive memory foam mattress brand focused on eco-friendly sleep solutions. Rosie writes more posts on the Amerisleep blog about the science of sleep, eco-friendly living, leading a healthy lifestyle and more. -- This feed and its contents are the property of The Huffington Post, and use is subject to our terms. It may be used for personal consumption, but may not be distributed on a website.
Source: Healthy Living - The Huffington Post - October 16, 2015 Category: Consumer Health News Source Type: news

Being overweight, smoking and drinking ‘cuts lifespan by 23 years’
The reduction in lifespan from a combination of diabetes, heart attack and a stroke is similar to that of people diagnosed with HIV, scientists from Cambridge University found.
Source: the Mail online | Health - July 8, 2015 Category: Consumer Health News Source Type: news

Unhealthy lifestyle can knock 23 years off lifespan
Suffering from heart disease, stroke and type two diabetes could knock 23 years off life and yet they are preventably for eight out of 10 people
Source: Telegraph Health - July 7, 2015 Category: Consumer Health News Tags: cambridge university symptoms cures stroke heart disease diabetes Source Type: news

Longer sleep linked to stroke
Conclusion This cohort study found that, overall, people who sleep for more than eight hours have a 46% increased risk of stroke. When analysed separately, there was no statistically significant association for men, but a much higher increased risk for women, of 80%. A major strength of the study is the number of potential confounding factors that the researchers tried to account for, including many cardiovascular risk factors. However, it did not account for other illnesses such as sleep apnoea or cancer, which may have had an effect on the amount of sleep and risk of stroke. In addition, the study is reliant on the i...
Source: NHS News Feed - February 26, 2015 Category: Consumer Health News Tags: Lifestyle/exercise Neurology Older people Source Type: news

Sleeping more than eight hours raises stroke risk, Cambridge University warns
Older people who slept for longer than eight hours were more likely to have a stroke within 10 years
Source: Telegraph Health - February 25, 2015 Category: Consumer Health News Source Type: news

Inactivity 'twice as deadly' as obesity
Conclusion This study’s strengths included its large size and long follow-up period. Researchers also took into account a large number of factors (called confounders) that might have influenced the risk of death, such as diet, smoking history and alcohol intake, although it is still possible that both measured and unmeasured confounders influenced mortality rates. The study had one important limitation. It only measured people’s BMI (calculated by combining their weight and height) and their physical activity once, at the start of the study. It is quite possible that people’s BMI changed over time, and that this wou...
Source: NHS News Feed - January 15, 2015 Category: Consumer Health News Source Type: news

Tomato extract's heart effects exaggerated
ConclusionThis study found that the blood vessels in people with cardiovascular disease who were taking statins dilated more after they were treated with a chemical called acetylcholine if they had been taking lycopene every day for two months, compared to those taking placebo pills.The lycopene tablet had no significant effect on any of the other outcomes the researchers looked at, and no effect in healthy volunteers, although it did increase lycopene levels in the blood.  Although impaired endothelial function is a known predictor of future heart disease, this is, at best, a surrogate outcome. It is no substitute for fo...
Source: NHS News Feed - June 10, 2014 Category: Consumer Health News Tags: Heart/lungs Food/diet Source Type: news

Tomato extract effects exaggerated
ConclusionThis study found that the blood vessels in people with cardiovascular disease who were taking statins dilated more after they were treated with a chemical called acetylcholine if they had been taking lycopene every day for two months, compared to those taking placebo pills.The lycopene tablet had no significant effect on any of the other outcomes the researchers looked at, and no effect in healthy volunteers, although it did increase lycopene levels in the blood.  Although impaired endothelial function is a known predictor of future heart disease, this is, at best, a surrogate outcome. It is no substitute for fo...
Source: NHS News Feed - June 10, 2014 Category: Consumer Health News Tags: Heart/lungs Food/diet Source Type: news

ACE inhibitor use may be linked to kidney failure
Conclusion ACE inhibitors and ARAs are recognised as a potential risk factor for AKI in some patients. This particular study has tried to estimate the possible size of the problem, but its findings should be viewed with some caution. As the authors point out: some of the conditions these drugs are prescribed for are themselves a risk factor for AKI changes in hospital coding and better recognition of AKI could explain the rise in admissions an ageing population leads to both increased prescribing of these drugs and an increased risk for AKI increased use of these drugs may be a marker for increased use of other...
Source: NHS News Feed - November 7, 2013 Category: Consumer Health News Tags: Medication Heart/lungs Source Type: news

Dementia rates dropping
Conclusion This study suggests that the prevalence of dementia in over 65s in 2011 is lower than would have been expected.  The study had many strengths, including the large number of people it interviewed from different areas and the consistent research methods adopted in 1991 and again in 2011, particularly using the same criteria to diagnose dementia at both time points. This means we can be relatively sure that its conclusions are reliable. That said, it does have some limitations to consider. The response rate in 2011 (56%) was much lower than in 1991 (80%). The study authors offer a number of explanations for this...
Source: NHS News Feed - July 17, 2013 Category: Consumer Health News Tags: Neurology Older people Medical practice Source Type: news