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O-013 Impact of stent-retriever tip design on distal embolization during mechanical thrombectomy - a randomized in vitro evaluation
ConclusionsWhen facing fragment-prone clots, the filter-tip SR significantly reduces the number of large clots (>1mm) that embolize distally during an MT procedure, which in turn may increase the chances of first-pass complete recanalization.Abstract O-013 Figure 1Disclosures J. Li: 1; C; Vesalio. R. Tiberi: 1; C; Vesalio. P. Bhogal: 1; C; Vesalio. 2; C; Perflow Medical, Phenox, Cerenovus, Neurovasc, Brainomix, Perfuze. 3; C; BRAIN Conference, BT Health Board. J. Buhk: 2; C; MicroVention, Stryker, Vesalio, Acandis. D. Behme: 1; C; Vesalio. 2; C; Acandis, Balt. A. Tomasello: 2; C; Medtronic, Balt, Cerus, Siemens, Vesalio...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Li, J., Tiberi, R., Bhogal, P., Buhk, J., Behme, D., Tomasello, A., Ribo, M. Tags: SNIS 20th annual meeting oral abstracts Source Type: research

E-223 Improved time to diagnosis with portable MR imaging
ConclusionPortable MRI is a promising innovation with the aim to expand patient access and improve diagnostic times so that critical and potential lifesaving imaging diagnoses can be promptly treated with the urgency that is required. While initial analysis provides evidence that portable MRI has advantages over conventional MRI systems including workflow efficiency and improved patient imaging times, this will need to be compared to the unfortunate negative drawbacks of lessened image resolution and limited imaging sequences that come with the convenience of portable MRI systems. If the hypothesis is further corroborated,...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Richardson, O., Richardson, A., Mukherjee, S. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

P31 Patients treated with the pipeline shield flow diverter enrolled within the INSPIRE study: primary analysis
ConclusionThe primary analysis of the INSPIRE study is still ongoing. During the conference, we will provide safety and efficacy data on a large and heterogenous patient population treated with the Pipeline Shield device, with adjudication by CEC and Imaging Core Lab ensuring high quality of these data.ReferencesPeriprocedural Outcomes and Early Safety with the use of the Pipeline Flex Embolization Device with Shield Technology for Unruptured Intracranial Aneurysms: Preliminary Results from a Prospective Clinical Study. J Neurointerv Surg, 2017 Do you have any conflict of interest to declare?: YesConflict of Interest State...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Szikora, I., Turjman, F., Spelle, L., Holtmanspötter, M., Martinez-Galdamez, M., Lamin, S., Fiehler, J. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

P64 NIMBUS geometric clot extractor for tough clots: SPERO study results and clot composition
ConclusionsIn challenging cases with tough clot, first pass of NIMBUS retrieved clot richer in fibrin and lower in RBC content than clot retrieved with the first pass of standard MT devices.ReferencesFennell VS, Setlur Nagesh SV, Meess KM, Gutierrez L, James RH, Springer ME, Siddiqui AH. What to Do about Fibrin Rich ‘Tough Clots’? Comparing the Solitaire Stent Retriever with a Novel Geometric Clot Extractor in an in vitro Stroke Model. J Neurointerv Surg 2018 Sep;10(9):907–910. DOI: 10.1136/Neurintsurg-2017-013507. EPUB 2018 Jan 19. PMID: 29352061. Do you have any conflict of interest to declare?: YesConf...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: van den Berg, R., Ribo, M., Arnberg, F., Estrade, L., Thornton, J., Tomasello Weitz, A., Gontu, V., Karam, A., Hernandez, D., Clarencon, F., Buhk, J.-H., Wiesmann, M., Nouri, N., Bricout, N., Desal, H., Januel, A., Doyle, K., Liebeskind, D., Brouwer, P., Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

P81 Novel synthetic clot analogs for in-vitro stroke modelling
ConclusionSelected synthetic clots can successfully be implemented in an in-vitro training environment of mechanical thrombectomy. The clots’ different properties might serve to mimic fibrin-rich and red blood cell human thrombi.ReferencesNadine Wortmann, Thomas Andersek, Helena Guerreiro, et al. Development of Synthetic Thrombus Models to Simulate Stroke Treatment in a Physical Neurointerventional Training Model, All Life 2022;15:1, 283–301, DOI:10.1080/26895293.2022.2046181Spallek J, Kuhl J, Wortmann N, et al. Design for Mass Adaptation of the Neurointerventional Training Model Hannes with Patient-specific An...
Source: Journal of NeuroInterventional Surgery - August 29, 2022 Category: Neurosurgery Authors: Guerreiro, H., Wortmann, N., Andersek, T., Ngo, T., Frölich, A., Krause, D., Fiehler, J., Kyselyova, A., Flottmann, F. Tags: 14th Congress of the European Society of Minimally Invasive Neurological Therapy 2022 Meeting Abstracts Source Type: research

Endovascular thrombectomy without versus with intravenous thrombolysis in acute ischemic stroke: a non-inferiority meta-analysis of randomized clinical trials
Conclusions This meta-analysis suggests that EVT alone is non-inferior to IVT plus EVT for several, but not the most stringent, non-inferiority margins.
Source: Journal of NeuroInterventional Surgery - February 16, 2022 Category: Neurosurgery Authors: Lin, C.-H., Saver, J. L., Ovbiagele, B., Huang, W.-Y., Lee, M. Tags: Open access, Ischemic stroke Source Type: research

E-054 The river trial: A prospective single arm trial of stenting the transverse sigmoid sinuses with the river stent in patients with idiopathic intracranial hypertension resistant to medical therapy
ConclusionsThe results so far have shown safety and probable efficacy. Enrollment and follow-up are ongoing and updated results will be presented at the conference.Disclosures A. Patsalides: None.
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Patsalides, A. Tags: Electronic poster abstracts Source Type: research

E-085 Interventional and diagnostic neuroradiology fellowship education in the COVID-19 era
ConclusionElective neurointerventional case numbers decreased as a result of the COVID-19 pandemic, particularly impacting the fourth quarter of the 2019-2020 academic year (April - June). Similarly, there was a sizable decrease in diagnostic neuroradiology case volume during this same time period. The decrease in procedural and diagnostic neuroradiology cases raised concerns regarding the educational experience for both diagnostic and neurointerventional radiology fellows. However, as a result of decreased case volume, fellowship education was rapidly augmented with a wide variety of online webinars, lectures, case confer...
Source: Journal of NeuroInterventional Surgery - July 26, 2021 Category: Neurosurgery Authors: Wilseck, Z., Bamezai, S., Novakovic, N., Copelan, A., Wilseck, J., Srinivasan, A., Pandey, A., Thompson, G., Gemmete, J., Chaudhary, N. Tags: Electronic poster abstracts Source Type: research

Does Reducing the Duration from Symptom Onset to Recanalization Improve the Results of Intracranial Mechanical Thrombectomy in the Elderly?
Authors: Komatsubara K, Dembo T, Sato E, Sasamori H, Torii M, Shiokawa Y, Hirano T Abstract Endovascular recanalization for acute major cerebral artery occlusion is effective within a short time after symptom onset. However, its efficacy in the elderly remains unknown. We assessed the efficacy of our comprehensive stroke center's reduction of this time in 28 consecutive patients for elderly patients (defined as patients aged ≥75 years) with acute major cerebral artery occlusion treated with intravenous injection of tissue plasminogen activator, followed by thrombus retrieval by endovascular therapy. The patients ...
Source: Neurologia Medico-Chirurgica - February 1, 2017 Category: Neurosurgery Tags: Neurol Med Chir (Tokyo) Source Type: research

Bioactive versus bare platinum coils for the endovascular treatment of intracranial aneurysms: systematic review and meta-analysis of randomized clinical trials
Conclusions Bioactive coils ensure a higher rate of medium-term complete aneurysm occlusion while reducing the rate of residual neck aneurysms compared with bare coiling in the mid-term. Hydrogel coils reduce residual aneurysms compared with bare coils. While there is level 1a evidence to show more complete aneurysm occlusion, longer term follow-up is needed to determine if this translates into clinical significance.
Source: Journal of NeuroInterventional Surgery - August 11, 2016 Category: Neurosurgery Authors: Broeders, J. A., Ahmed Ali, U., Molyneux, A. J., Poncyljusz, W., Raymond, J., White, P. M., Steinfort, B. Tags: Hemorrhagic stroke Source Type: research

The strokes that killed Churchill, Roosevelt, and Stalin.
Abstract From February 4 to 11, 1945, President Franklin D. Roosevelt of the United States, Soviet Union Premier Joseph Stalin, and British Prime Minister Winston Churchill met near Yalta in Crimea to discuss how post-World War II (WWII) Europe should be organized. Within 2 decades of this conference, all 3 men had died. President Roosevelt died 2 months after the Yalta Conference due to a hemorrhagic stroke. Premier Stalin died 8 years later, also due to a hemorrhagic stroke. Finally, Prime Minister Churchill died 20 years after the conference because of complications due to stroke. At the time of Yalta, these 3 ...
Source: Neurosurgical Focus - June 30, 2016 Category: Neurosurgery Authors: Ali R, Connolly ID, Li A, Choudhri OA, Pendharkar AV, Steinberg GK Tags: Neurosurg Focus Source Type: research

Spatial neglect
Giuseppe Vallar, MD, specialty in Neurology, Italian, was born in Milan. Department of Psychology, University of Milano-Bicocca, & IRCCS Italian Auxological Institute, Milan, Italy. Email: giuseppe.vallar@unimib.it Giuseppe Vallar since 1999, Professor of Psychobiology and Physiological Psychology and, since 2009, the Director of the Specialty School in Neuropsychology, of the Department of Psychology of the University of Milan-Bicocca-Milan, Italy. Since 2005 Giuseppe Vallar is the Head of the Neuropsychological Laboratory, of the Italian Auxological Institute, Saint Luca Hospital, Milan, Italy. Previously, Giuseppe V...
Source: Journal of Neurology, Neurosurgery and Psychiatry - August 13, 2015 Category: Neurosurgery Tags: Stroke PRESENTATION ABSTRACTS - DAY 2 Source Type: research

Reflections on the lessons of the recent endovascular stroke trials
Science is simply common sense at its best, that is, rigidly accurate in observation, and merciless to fallacy in logic. Thomas Henry Huxley As the stroke community is invigorated by the recent results of the four trials showing the overwhelming efficacy of endovascular therapy for large vessel occlusion,1–4 we should reflect upon lessons that were learned that may help future clinical initiatives. It has been almost 16 years since the PROACT-II trial showed a 15% absolute difference in outcomes in patients treated with intra-arterial pro-urokinase for a middle cerebral artery (MCA) occlusion compared with medic...
Source: Journal of NeuroInterventional Surgery - April 13, 2015 Category: Neurosurgery Authors: Gupta, R. Tags: Editor ' s column Source Type: research

Thrombectomy for acute ischemic stroke: an evidence-based treatment
Just 2 years ago, at the International Stroke Conference in Honolulu, Hawaii, USA, the Interventional Management of Stroke (IMS III),1 Mechanical Retrieval and Recanalization of Stroke Clots Using Embolectomy (MR RESCUE),2 and SYNTHESIS-Expansion3 trials were presented and concurrently published in The New England Journal of Medicine. The overarching message to the medical community and lay press was that these studies provided unambiguous evidence that mechanical thrombectomy was ineffective in treating acute stroke secondary to emergent large vessel occlusion (ELVO). The investigators were careful to emphasize the a...
Source: Journal of NeuroInterventional Surgery - April 13, 2015 Category: Neurosurgery Authors: Fiorella, D. J., Fargen, K. M., Mocco, J., Albuquerque, F., Hirsch, J. A., Chen, M., Gupta, R., Linfante, I., Mack, W., Rai, A., Tarr, R. W. Tags: Editorials Commentary Source Type: research

E-071 Organization of a Neurointerventional Fellowship Curriculum
The objective of this report is to present a comprehensive three -tier model for a Neurointerventional didactics program. Methods The model divides an annual Neurointerventional didactic curriculum in to three tiers: Introduction to Neurointervention Series: Basic concepts of Neurointervention. Implemented during the first two months of the academic year. Faculty/speaker driven. Total 20 sessions. See Table 1. Neurointervention Core Curriculum: Implemented during months 3 to 12 of the academic year. Faculty/speaker moderated; more interactive. Total 30 sessions. See. Table 2. Neurointervention Advanced Didactics: Period...
Source: Journal of NeuroInterventional Surgery - July 26, 2014 Category: Neurosurgery Authors: Garg, A. Tags: Electronic poster abstracts Source Type: research