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Cognitive Impairment After Stroke and Treatment With Fluoxetine: A Planned Analysis of the AFFINITY Randomized Controlled Trial
Am J Geriatr Psychiatry. 2022 Aug 20:S1064-7481(22)00494-8. doi: 10.1016/j.jagp.2022.08.002. Online ahead of print.NO ABSTRACTPMID:36115731 | DOI:10.1016/j.jagp.2022.08.002
Source: Am J Geriatr Psychia... - September 17, 2022 Category: Geriatrics Authors: Osvaldo P Almeida Graeme J Hankey Andrew Ford Christopher Etherton-Beer Leon Flicker Maree L Hackett AFFINITY Trial Collaboration Source Type: research

Cognitive Impairment After Stroke and Treatment with Fluoxetine: A Planned Analysis of the AFFINITY Randomised Controlled Trial
Strokes increase the risk of cognitive impairment and dementia, and the risk of post-stroke cognitive decline does not subside with time.1 Selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine, display neuroprotective and neuro-regenerative properties in animal models of brain ischaemia,2 raising hope that their use could lessen the detrimental effects of stroke on cognition.
Source: The American Journal of Geriatric Psychiatry - August 19, 2022 Category: Geriatrics Authors: Osvaldo P. Almeida, Graeme J. Hankey, Andrew Ford, Christopher Etherton-Beer, Leon Flicker, Maree L. Hackett, AFFINITY Trial Collaboration Tags: Letter to the Editor Source Type: research