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The Preventive Antibiotics in Stroke Study (PASS): a pragmatic randomised open-label masked endpoint clinical trial
Publication date: Available online 20 January 2015 Source:The Lancet Author(s): Willeke F Westendorp , Jan-Dirk Vermeij , Elles Zock , Imke J Hooijenga , Nyika D Kruyt , Hans J L W Bosboom , Vincent I H Kwa , Martijn Weisfelt , Michel J M Remmers , Robert ten Houten , A H C M (Tobien) Schreuder , Sarah E Vermeer , Ewout J van Dijk , Diederik W J Dippel , Marcel G W Dijkgraaf , Lodewijk Spanjaard , Marinus Vermeulen , Tom van der Poll , Jan M Prins , Frederique H Vermeij , Yvo B W E M Roos , Ruud P Kleyweg , Henk Kerkhoff , Matthijs C Brouwer , Aeilko H Zwinderman , Diederik van de Beek , Paul J Nederkoorn Background In a...
Source: The Lancet - January 21, 2015 Category: Journals (General) Source Type: research

Update of the Preventive Antibiotics in Stroke Study (PASS): statistical analysis plan
Conclusions: The data from PASS will establish whether preventive antibiotic therapy in acute stroke improves functional outcome by preventing infection and will be analyzed according to this pre-specified SAP.Trial registration: Current controlled trials; ISRCTN66140176. Date of registration: 6 April 2010.
Source: Trials - October 1, 2014 Category: Journals (General) Authors: Willeke WestendorpJan-Dirk VermeijDiederik DippelMarcel DijkgraafTom van der PollJan PrinsFrederique VermeijYvo RoosMatthijs BrouwerAeilko ZwindermanDiederik van de BeekPaul Nederkoorn Source Type: research

Update on the Preventive Antibiotics in Stroke Study (PASS): a randomised controlled phase 3 clinical trial
Conclusion: The data from PASS will establish whether preventive antibiotic therapy in acute stroke improves functional outcome by preventing infection. In this update, we changed our primary outcome analysis from dichotomisation to ordinal regression analysis.Trial registration: Current controlled trials; ISRCTN66140176. Date of registration: 6 April 2010.
Source: Epidemiologic Perspectives and Innovations - April 21, 2014 Category: Epidemiology Authors: Willeke F WestendorpJan-Dirk VermeijNan van GelovenDiederik WJ DippelMarcel GW DijkgraafTom van der PollJan M PrinsLodewijk SpanjaardFrederique H VermeijPaul J NederkoornDiederik van de Beek Source Type: research