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Management dilemma in a rare case of pituitary apoplexy with akinetic mutism in the setting of ruptured junctional brain aneurysm: A case report and literature review
CONCLUSION: Pituitary apoplexy with ruptured A1-Acom junction aneurysm with nonfunctioning pituitary macroadenoma is rare, and its presentation with akinetic mutism has not been reported. As there is scarce literature suggesting an association between pituitary apoplexy and ruptured aneurysm, it is challenging to comment regarding its pathogenesis. Although akinetic mutism generally has a poor prognosis, it may respond to Levodopa with a better outcome.PMID:36751455 | PMC:PMC9899474 | DOI:10.25259/SNI_942_2022
Source: Surgical Neurology International - February 8, 2023 Category: Neurosurgery Authors: Vikas Chandra Jha Mohammad Shahnawaz Alam Vivek Sharan Sinha Rahul Jain Source Type: research

Co-occurrence of cadasil and a parkinsonian syndrome: a report of two cases and review of the literature
Conclusions To our knowledge this represents the first autopsy-confirmed case of CADASIL with coexistent idiopathic Parkinson’s disease in a patient with a novel NOTCH3 mutation. We also report on a new genetically confirmed case of CADASIL presenting as progressive Parkinsonism.
Source: Journal of Neurology, Neurosurgery and Psychiatry - May 8, 2017 Category: Neurosurgery Authors: Murray, N., Pepper, E., Blackie, J., Ronan, A., Sugo, E. Tags: Abstracts Source Type: research

Successful Management of Hemorrhage-associated Hemiballism after STN DBS with Pallidal Stimulation: A Case Report
Conclusion In our case pallidal DBS was effective in treating hemiballism that arose as a result of traumatic displacement of STN DBS electrodes. Medical management and changes in stimulation parameters failed to produce any significant change in the hemiballism. This report is only the third of its kind in the literature wherein hemiballism arising as a result of STN damage after DBS was successfully treated with pallidal stimulation.
Source: World Neurosurgery - July 10, 2015 Category: Neurosurgery Source Type: research

Dopamine dysregulation syndrome in Parkinson's disease: from clinical and neuropsychological characterisation to management and long-term outcome
Conclusions Clinicians should be aware of risk factors predisposing to DDS. Duodenal levodopa infusion and, less consistently, STN-DBS were more commonly associated with DDS remission. Effective caregiving plays a key role in long-term behavioural outcome.
Source: Journal of Neurology, Neurosurgery and Psychiatry - February 6, 2014 Category: Neurosurgery Authors: Cilia, R., Siri, C., Canesi, M., Zecchinelli, A. L., De Gaspari, D., Natuzzi, F., Tesei, S., Meucci, N., Mariani, C. B., Sacilotto, G., Zini, M., Ruffmann, C., Pezzoli, G. Tags: JNNP Patients' choice, Drugs: CNS (not psychiatric), Parkinson's disease, Stroke, Drugs misuse (including addiction) Movement disorders Source Type: research