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C-Reactive Protein and Risk of Parkinson's Disease: A Systematic Review and Meta-Analysis
Conclusions: This meta-analysis revealed that PD is associated with an increase of CRP levels. CRP might be a risk factor for PD or PD leads to an inflammatory response. Introduction Parkinson's disease (PD) is one of the most complex neuro-degenerative disorders next to Alzheimer's disease. It is characterized by bradykinesia, tremor, rigidity, abnormal postural, and gait (1). PD has been recognized by the selective loss of dopaminergic neurons within the substantia nigra pars compacta, whereas the exact etiology remains elusive (2). Previously, multiple inferences have reviewed the environmental a...
Source: Frontiers in Neurology - April 16, 2019 Category: Neurology Source Type: research

Neuropathological Correlates of Visual Hallucinations in Parkinsonism (S03.006)
CONCLUSIONS: These findings suggest that Lewy-related pathology is specifically implicated in the genesis of VH in PD and related disorders. Plaque and tangles, although present in many cases, did not contribute to the occurrence of VH.Supported by: The Brain Donation Program is supported by the National Institute of Neurological Disorders and Stroke (U24 NS072026 National Brain and Tissue Resource for Parkinson's Disease and Related Disorders), the National Institute on Aging (P30 AG019610 Arizona Alzheimer's Disease Core Center), the Arizona Department of Health Services (contract 211002, Arizona Alzheimer's Research Cen...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Morshed, T., Jacobson, S., Beach, T., Adler, C., Shill, H., Caviness, J., Belden, C., Sue, L., Sabbagh, M., Hu, C., Davis, K. Tags: S03 Parkinson ' s Disease Source Type: research