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Effect of fluoxetine on HIF-1 α- Netrin/VEGF cascade, angiogenesis and neuroprotection in a rat model of transient middle cerebral artery occlusion.
Effect of fluoxetine on HIF-1α- Netrin/VEGF cascade, angiogenesis and neuroprotection in a rat model of transient middle cerebral artery occlusion. Exp Neurol. 2020 Apr 12;:113312 Authors: Hu Q, Liu L, Zhou L, Lu H, Wang J, Chen X, Wang Q Abstract Fluoxetine is one of the most promising drugs for improving clinical outcome in patients with ischemic stroke. This in vivo study investigated the hypothesis that fluoxetine may affect HIF-1α-Netrin/VEGF cascade, angiogenesis and neuroprotection using a rat model of transient middle cerebral artery occlusion (tMCAO). The rats were given fluoxetine or salin...
Source: Experimental Neurology - April 11, 2020 Category: Neurology Authors: Hu Q, Liu L, Zhou L, Lu H, Wang J, Chen X, Wang Q Tags: Exp Neurol Source Type: research